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Proteomics and Metabolomics Shared Resource

Published Research

Citation Reference Language for Use of Shared Resource

“Proteomics and Metabolomics Shared Resource services are supported by the Comprehensive Cancer Center of Wake Forest Baptist Medical Center NCI CCSG P30CA012197 grant.”


Program Key: CPC = Cancer Prevention and Control Program; CRP = Clinical Research Program; TPR = Tumor Progression and Recurrence Program; CBB = Cancer Biology and Biochemistry Program
  1. Martel C, Li W, Fulp B, Platt AM, Gautier EL, Westerterp M, Bittman R, Tall AR, Chen SH, Thomas MJ(TPR), Kreisel D, et al.. Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice. J Clin Invest. 2013;123(4): 1571-9. PMC3613904.
  2. Youm YH, Kanneganti TD, Vandanmagsar B, Zhu X, Ravussin A, Adijiang A, Owen JS, Thomas MJ(TPR), Francis J, Parks JS(TPR), Dixit VD. The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence. Cell Rep. 2012;1(1): 56-68. PMC3883512.
  3. Pandya DN, Pailloux S, Tatum D, Magda D, Wadas TJ(CBB). Di-macrocyclic terephthalamide ligands as chelators for the PET radionuclide zirconium-89. Chem Commun (Camb). 2015;51(12): 2301-3. PMC4507282.
  4. Ghosh S, Ucer KB, D'Agostino R(CPC), Grant K, Sirintrapun J, Thomas M(TPR), Hantgan R, Bharadwaj M, Gmeiner WH(CBB). Non-Covalent Assembly of Meso-tetra-4-Pyridyl Porphine with Single-Stranded DNA to Form Nano-sized Complexes with Hydrophobicity-Dependent DNA Release and Anti-Tumor Activity. Nanomedicine. 2014;10: 451-61. PMC3946208.
  5. Gu Z, Wu J, Wang S, Suburu J, Chen H, Thomas MJ(TPR), Shi L, Edwards IJ(TPR), Berquin IM, Chen YQ(CBB). Polyunsaturated fatty acids affect the localization and signaling of PIP3/AKT in prostate cancer cells. Carcinogenesis. 2013;34(9): 1968-75. PMC3765042.
  6. Hou TY, Monk JM, Fan YY, Barhoumi R, Chen YQ(CBB), Rivera GM, McMurray DN, Chapkin RS. n-3 polyunsaturated fatty acids suppress phosphatidylinositol 4,5-bisphosphate-dependent actin remodelling during CD4(+) T-cell activation. Biochemical Journal. 2012;443: 27-37. PMC3814172.
  7. Hill TK, Abdulahad A, Kelkar SS, Marini FC(TPR), Long TE, Provenzale JM, Mohs AM(CBB). Indocyanine Green-Loaded Nanoparticles for Image-Guided Tumor Surgery. Bioconjug Chem. 2015;26(2): 294-303. PMC4373659.
  8. Chen H, Gu Z, Zhang H, Wang M, Chen W, Lowther WT(CBB), Chen YQ(CBB). Expression and purification of integral membrane Fatty Acid desaturases. PLoS One. 2013;8(3): e58139. PMC3592867.
  9. O'Flaherty JT, Wooten RE, Samuel MP, Thomas MJ(TPR), Levine EA(CRP), Case LD(CRP), Akman SA, Edwards IJ(TPR). Fatty acid metabolites in rapidly proliferating breast cancer. PLoS One. 2013;8(5): e63076. PMC3642080.
  10. Pollard RD, Fulp B, Samuel MP, Sorci-Thomas MG, Thomas MJ(TPR). The conformation of lipid-free human apolipoprotein A-I in solution. Biochemistry. 2013;52(52): 9470-81. PMC3926756.
  11. Mims J, Bansal N, Bharadwaj MS, Chen X, Molina AJ, Tsang AW(TPR), Furdui CM(CBB). Energy Metabolism in a Matched Model of Radiation Resistance for Head and Neck Squamous Cell Cancer. Radiat Res. 2015;183(3): 291-304. PMC4465128.
  12. Bansal N, Mims J, Kuremsky JG, Olex AL, Zhao W, Yin L, Wani R, Qian J, Center B, Marrs GS, Porosnicu M(CRP), Fetrow JS, Tsang AW(TPR), Furdui CM(CBB).  Broad phenotypic changes associated with gain of radiation resistance in head and neck squamous cell cancer. Antioxid Redox Signal. 2014;21(2):221-36. PMC4060837.
  13. Randall LM, Manta B, Hugo M, Gil M, Batthyàny C, Trujillo M, Poole LB(CBB), Denicola A. Nitration transforms a sensitive peroxiredoxin 2 into a more active and robust peroxidase. J Biol Chem. 2014;289(22):15536-43. PMC4140909.
  14. Haynes AC, Qian J, Reisz JA, Furdui CM(CBB), Lowther WT(CBB). Molecular basis for the resistance of human mitochondrial 2-cys peroxiredoxin 3 to hyperoxidation. J Biol Chem. 2013;288(41):29714-23. PMC3795269.
  15. Wani R, Qian J, Yin L, Bechtold E, King SB(CBB), Poole LB(CBB), Paek E, Tsang AW(TPR), Furdui CM(CBB). Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species. Proc Natl Acad Sci U.S.A. 2011;108(26):10550-5. PMC3127936.


Quick Reference

Proteomics and Metabolomics Shared Resource
Cristina M. Furdui, PhD


Mark Lively


Technical Staff
Anderson O'Brien Cox

Technical Staff
Jingyun Lee


Technical Staff
Mark Morris


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