Tumor Tissue Shared Resource - Services We Provide

 


 

  • Consultation: The directors provide expert consultation with investigators on matters such as IRB and IACUC approval, sample selection, processing, and data interpretation. 
  • Banked tumor and matched normal tissue specimens: The Tumor Tissue Lab of the TTPSR has over 44,000 vials encompassing human tumor tissue specimens with matched adjacent normal tissues from both primary and metastatic lesions available for cancer research. After requests for provision of samples are reviewed and approved by the Tumor Tissue Committee of the TTPSR, samples are provided to investigators, along with tissue morphology and RNA integrity data.
  • Collection of fresh prospective tissue:  WFBCCC investigators may use the TTPSR infrastructure to collect fresh tissue specimens prospectively. The Shared Resource assists investigators with design of the collection protocol, matters of regulatory approval, sample selection and collection, processing, quality control, and data interpretation.  
  • Procurement of tissue samples required by WFBCCC-initiated clinical trials and national cooperative group trials: Another function of the TTPSR Laboratory is to obtain and process specimens requested by WFBCCC investigator-initiated trials and national cooperative group trials such as the Alliance for Clinical Trials, The Cancer Genome Atlas, and the Gynecologic Oncology Group.
  • Human Pathology Services: The Human Pathology Lab provides support for routine histological and cytochemical applications for tissues specifically collected for cancer research.  The Human Pathology Lab also offers the expertise of a certified pathologist for: (i) initial consultation for design of a project, (ii) specific needs for tissue processing, (iii) interpretation of data, and (iv) support for grant applications. 
  • Comparative Pathology Service: The Comparative Pathology Lab is a fully-functional laboratory that emphasizes the diagnostic and experimental pathology of both rodent and nonhuman primate models of cancer. The lab provides pathology support to investigators for: (i) diagnostic pathology, (ii) experimental design and tissue collection, (iii) tissue evaluation and lesion interpretation, and (iv) generation of preliminary data for publications and grants. In addition to routine histology and specialized cytochemical stains, the laboratory has a large bank of approximately 50 validated immunohistochemical markers relevant to cancer.

Quick Reference

Tumor Tissue Shared Resource
Tiffany Walker West
Tumor Tissue Lab

336-716-3721

twalkerw@wakehealth.edu

Libby Williams
Tumor Tissue Lab

336-716-5355

lmcwilli@wakehealth.edu

Greg Kucera, PhD
Tumor Tissue Lab

336-716-6348

gkucera@wakehealth.edu

Tammy Sexton
Human Pathology Lab

336-716-6012

tsexton@wakehealth.edu

Shadi Qasem, MD
Human Pathology Lab

336-716-2640

sqasem@wakehealth.edu

Lisa O'Donnell
Comparative Pathology Lab

336-716-1549

lodonnel@wakehealth.edu

David Caudell, DVM, PhD
Comparative Pathology Lab

336-716-4763

dcaudell@wakehealth.edu

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Last Updated: 09-06-2016
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