Action to Control Cardiovascular Risk in Diabetes (ACCORD) Follow-Up Study – Memory in Diabetes Follow-Up Study

Short Study Name (acronym):ACCORDION-MIND

Long Name:Action to Control Cardiovascular Risk in Diabetes (ACCORD) Follow-Up Study – Memory in Diabetes Follow-Up Study

Investigators (list PI first):
Jeff Williamson, MD

Funding Agency:
National Heart Lung and Blood Institute/National Institute on Aging

Funding Dates:
2011 - 2014

Research questions or aims: 

The primary aim of this follow-up study is to further delineate how diabetes affects the brain.  The aging of the cohort, longer follow-up and additional measure of cognitive function and a third MRI will allow us to study the longitudinal effects of diabetes-related factors on the brain, and to investigate how these factors, in combination with older age, interact leading to worse outcomes.

Target population:
A subsample of 2800 people who participated in the National Heart Lung and Blood Institute (NHLBI) randomized factorial clinical trial Action to Control Cardiovascular Risk in Diabetes (ACCORD) follow-up study – ACCORDION.  The participants will be the same participants recruited as part of the preceding ACCORD-MIND.

Target # to enroll:
The participants will be the same participants recruited as part of the preceding ACCORD-MIND.

Target Dates of enrollment: 

Types of assessments and questionnaires:
Mini-Mental State Examination (MMSE), Rey Auditory Verbal Learning Test, Digit Symbol Substitution Test (DSST), Stroop Test, MRI

Other data collected:
Telephone Interview for Cognition (TICS), Functional Assessment Questionnaire (FAQ)

Project Manager Contact Info:
Nancy Woolard

Email: nwoolard@wakehealth.edu
Phone: 336-713-8585

 

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