Action to Control Cardiovascular Risk in Diabetes (ACCORD) Follow-Up Study

 Short Study Name (acronym):ACCORDION

 Long Name:Action to Control Cardiovascular Risk in Diabetes (ACCORD) Follow-Up Study

Investigators (list PI first):
William Applegate, MD

Funding Agency:
National Heart Lung and Blood Institute/National Institute on Aging

Funding Dates:
2011 - 2015

Research questions or aims:

  1. Does a therapeutic strategy that initially targeted an A1C of < 6.0% for a mean of 3.5 years reduce the long-term mean 10 year risk of major CVD events after 6.5 additional years of follow-up compared to a strategy that initially targeted an A1C of between 7 and 7.9%?
  2. Does a therapeutic strategy that initially used a fibrate to raise HDL-C/lower triglyceride levels and a statin for treatment of LDL-C for a mean of almost 5 years reduce the long-term mean 10 year risk of major CVD events after 5 additional years of follow-up compared to a strategy that only used a statin for treatment of LDL-C?
  3. Does a therapeutic strategy that initially targeted a systolic blood pressure (SBP) of < 120 mm Hg for a mean of almost 5 years reduce the long-term mean 10 year risk of major CVD events after 5 additional years of follow-up compared to a strategy that targeted a SBP of < 140 mm Hg? 

Target population:
The participants will be the same participants recruited as part of the preceding ACCORD study.

Target # to enroll:
The participants will be the same participants recruited as part of the preceding ACCORD study.

Target Dates of enrollment:
Will be contacting and seeing these participants from August 2011 through 2012.

Types of assessments and questionnaires:
Medical history, outcomes questionnaires, physical exam, medications, quality of life questionnaire, blood draw for A1c.

Project Manager Contact Info:

Ashley Widener
Email:  awidener@wakehealth.edu
Phone: 336-713-8014

 

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