Cooperative Lifestyle Intervention Program (CLIP)

Long Name:  Cooperative Lifestyle Intervention Program (CLIP)  

The CLIP study is a 3-arm 18-month randomized, controlled trial of the effectiveness of physical activity, with and without weight loss, in the treatment of mobility disability in 288 older (60-79 years), overweight/obese men and women who have evidence of CVD or the metabolic syndrome.  Participants are randomized to one of the 3 intervention groups: 1) a successful aging education control condition; 2) a group treatment program for physical activity; and 3) a lifestyle intervention that is designed to promote weight loss and increase physical activity.  The primary aim of the study is to compare the effects of the three treatments on 18-month change in mobility disability, as assessed by the distance walked during a 400M walk test.  A secondary aim is to test the effects of the interventions on change in: CVD risk factors (high-sensitivity C-reactive protein; lipid profiles; glucose and insulin; blood pressure), physical activity and dietary intake, body composition, and on health-related quality of life (HRQL).  The public health relevance of the trial lies in the fact that the interventions will be delivered in conjunction with Cooperative Extension Centers. 

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Last Updated: 10-21-2013
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