Research on Optimal Recovery Practices in Breast Cancer (RESTORE)
Long Name: Research on Optimal Recovery Practices in Breast Cancer (RESTORE)
Breast cancer is one of the most prevalent diseases among women. Although advances in medical and surgical treatments have led to increased survivorship, there has been a general lag in the development of post-operative health care programs. RESTORE is a randomized control clinical trial designed to test the benefits of exercise on health and well-being of 100 adult women of all ages recently treated for breast cancer. The study groups include: 1) usual care consisting of patient education, and 2) a comprehensive program of tailored exercise which includes a lymphedema-specific exercise prevention program plus patient education. Identification of eligible women occurs through medical and surgical oncologist’ offices and through the WFU Comprehensive Cancer Center. Age and stage eligible women are thusly enrolled 2 to 6 weeks post surgery and followed for 18 months. The exercise programs are center-based and tapered to home sessions to promote high adherence levels by integration into daily life. The comprehensive tailored exercise program focused on improving muscle strength and flexibility, and the lymphedema prevention program focuses specifically on arm exercises, massage techniques, and wearing of an elastic sleeve. Outcomes include change from baseline in 6-minute walk test, the FACT-B health – related quality of life scale, and the incidence of lymphedema during the 18- month period following randomization.