Multi-Center Trial to Evaluate Home-Based Assessment Methods for Alzheimer Disease Prevention Research in People Over 75 Years Old (HBA)
Short Study Name (acronym):HBA
Long Name:Multi-Center Trial to Evaluate Home-Based Assessment Methods for Alzheimer Disease Prevention Research in People Over 75 Years Old
Investigators (list PI first):
Kaycee Sink, MD
Jeff Williamson, MD
Franklin Watkins, MD
National Institute on Aging, through a grant to the Alzheimer’s Disease Cooperative Study
1/2008 – 6/2012
Research questions or aims:
- Establish the feasibility of the three in-house assessments methods—Mail in forms with live phone, automated telephone IVR technology and computer-based kiosk assessment and validate them by comparing them to traditional evaluation instruments.
- To evaluate the ability of the brief instruments proposed here to capture rate of change as an outcome for primary prevention trials.
- To examine medication adherence as a performance based assessment of functional ability in all 3 methods.
Male and female age 75 years and older with a Mini Mental State Exam score of >=26, willing to take multi-vitamins provided by the study,able to answer and dial a telephone, have access to secure mail, with minimal computers skills or willingness to learn.
Dates of enrollment:
July 2007 – August 2008
Types of assessments and questionnaires:
Medical History, Demographics, height, weight, Vital Signs, Concomitant Medications, MMSE, MCI ADCS-ADL, Logical Memory Test, Boston Naming, Category Fluency, Digit Span, Trail Making Test (A & B), Digit Symbol Substitution, Immediate and Delayed Word Recall, East Boston Memory, Abbreviated TICS, QOL, Brief Cognitive Function Screening, Behavioral Scale, CGIC, Resource Use Inventory
Other data collected:
Study Website (if applicable): www.adcs.org/Studies/HBA.aspx
Coordinator Contact Info: