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Severe Weather Alert - Updated: 7:30 pm, January 18, 2018

All Wake Forest Baptist Health clinics will delay opening Friday, January 19 until 10am. Urgent Care – Clemmons and Urgent Care – Mocksville will also open Friday, January 19 at 10am. 
If you have questions, please contact the clinic directly.

Chemical Probes

Development of Chemical Approaches for the Quantitative Analysis of Protein Thiol Oxidative Modifications

This project is the product of collaboration with colleagues Drs. Leslie Poole (Department of Biochemistry) and S. Bruce King (Department of Chemistry) at Wake Forest. Over the past 10 years, our groups have developed chemical probes for investigating and quantifying oxidative modifications of protein cysteine thiols focusing in particular on sulfenic -SOH species (shown here).

The probes cover a broad range of reactivity profiles to fit various applications and are compatible with analysis by mass spectrometry, Western blotting and imaging [e.g., application of the BP1 reagent in imaging of tumor samples is shown under Head and Neck Cancer Project].



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Cristina Furdui

Office: 336-716-2697
Fax: 336-716-1214
Lab: 336-713-4073

Medical Center Blvd.
Winston-Salem, NC 27157
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Last Updated: 05-09-2016
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