Neonatology Research
Eight neonatology faculty are involved in research programs covering basic, translational and clinical research. Basic research includes studies in vascular physiology and intestinal development. Translational research includes animal models of bowel function and growth after bowel resection. Clinical studies are described below:
Current Clinical Studies 
Gene Targets for IVH
Principal Investigator: T. Michael O'Shea, MD, MPH
Funding: NIH
Study Type: Observational; multi-centered; NIH
Purpose: To assess the relative contribution of genetic factors to Grade 3-4 IVH
in preterm neonates 500-1250 grams (control matched--ie, normal CUS, gender, BW, and site).
ELGAN-2 (began October 2011)
Principal Investigator: T. Michael O'Shea, MD, MPH
Funding: NIH
Study Type: Observational; multi-centered; NIH
Purpose:
Pediatric Trials Network
Principal Investigator: T. Michael O'Shea, MD, MPH
Funding: NIH
Study Type: Observational; multi-centered; NIH
Purpose:
TOLSurf 
Principal Investigator: Jennifer B. Helderman, MD, MS
Study Type: Randomized trial; multicentered
Purpose: This is the randomized trial of late surfactant (after 7 days of age) in very
preterm infants with ventilator dependency.
ProPheno
Principal Investigator:Jennifer B. Helderman, MD, MS
Funding: NIH
Study Type: Randomized trial; multicentered
Purpose: This is a randomized trial of phenobarbital prophylaxis versus placebo for
term infants with a history of neonatal seizures. (recruitment has ended)
PEPC-2 (Prenatal Events - Postnatal Consequences)
(began October 2011)
Prinicipal Investigator: Lisa K. Washburn, MD
Funding: NIH
Study Type: Observational Cohort
Purpose: this is a study of cardiovascular metabolic outcomesof 19 year old children
Early Supplementation of Enteral Lipid in Infants with
Ostomies
Principal Investigator: Qing Yang, MD, PhD
Funding: The Gerber Foundation; Wake Forest Center for Botanical Lipids
Study Type: Randomized trial
Purpose: This is the randomized trial of fish oil/microlipid supplements for infants with ostomy