Neonatology Research

Eight neonatology faculty are involved in research programs covering basic, translational and clinical research.  Basic research includes studies in vascular physiology and intestinal development.  Translational research includes animal models of bowel function and growth after bowel resection. Clinical studies are described below:  

Current Clinical Studies 

 O'Shea T Michael D
Preterm Erythropoietin Neuroprotection Trial (PENUT
Principal Investigator
: T. Michael O'Shea, MD, MPH 
Coordinators: Warden
Study Type: Randomized multicenter trial
Purpose: To test the hypothesis that early high dose erythropoietin decreases the risk of brain damage in extremely preterm infants.   

Neonatal Neurobehavioral: Does it Predict Developmental Outcome at 2 Years of Age 
Principal Investigator
: T. Michael O'Shea, MD, MPH 
Coordinators: Warden
Study Type: multicenter observational
Purpose: To test the hypothesis that an abnormal neurobehavioral examination at 36 weeks postmenstrual age is predictive of adverse neurodevelopmental outcome at 2 years of age. 

Gene Targets for IVH       
Principal Investigator: T. Michael O'Shea, MD, MPH 
Funding: NIH
Study Type: Observational; multi-centered; NIH
Purpose: To assess the relative contribution of genetic factors to Grade 3-4 IVH
in preterm neonates 500-1250 grams (control matched--ie, normal CUS, gender, BW, and site).

ELGAN-2 (began October 2011)  
Principal Investigator: T. Michael O'Shea, MD, MPH 
Funding: NIH
Study Type: Observational; multi-centered; NIH
Purpose

Pediatric Trials Network 
Principal Investigator: T. Michael O'Shea, MD, MPH 
Funding: NIH
Study Type: Observational; multi-centered; NIH 
  Helderman Jennifer B






TOLSurf 
Principal Investigator:
Jennifer B. Helderman, MD, MS 
Coordinator: Warden
Study Type: Randomized trial; multicentered
Purpose: This is the randomized trial of late surfactant (after 7 days of age) in very preterm infants with ventilator dependency.

    Washburn Lisa K

 




PEPC-2 (Prenatal Events - Postnatal Consequences)
(began October 2011)                             
Prinicipal Investigator
: Lisa K. Washburn, MD
Coordinator: Scott
Funding: NIH
Study Type: Observational Cohort
Purpose: this is a study of cardiovascular metabolic outcomes of 19 year old children 

Yang Qing






Early Supplementation of Enteral Lipid in Infants with
Ostomies
Principal Investigator
: Qing Yang, MD, PhD
Funding: The Gerber Foundation; Wake Forest Center for Botanical Lipids
Study Type: Randomized trial
Purpose: This is the randomized trial of fish oil/microlipid supplements for infants with ostomy  

 

 

 

 

 

 

 

 

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