Christos Constantinidis, PhD
Ph.D., Johns Hopkins University, 1997
Research in the laboratory of Dr. Constantinidis aims to understand how neuronal activity in the cerebral cortex gives rise to cognitive functions. Experiments in recent years have focused on the posterior parietal and dorsolateral prefrontal cortex, two areas implicated in visual perception, attention, and working memory. Simultaneous neuronal recordings from multiple micro-electrodes during performance of cognitive tasks are addressing how these areas are functionally organized and how experience and learning modifies the properties of their neurons. Neuronal activity in these areas is also monitored under administration of drugs that produce cognitive effects, and at different stages of development. Computational and modeling approaches are then employed to understand the neural mechanisms that mediate complex cognitive functions such as the selective representation of an attended stimulus or its maintenance in memory.
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