Pending and Planned Projects

HIRREM for persisting post-concussion symptoms in athletes

To be organized in collaboration with the Sports Medicine Section in the Department of Family and Community Medicine at Wake Forest School of Medicine, this project will be a single site, randomized, single blind, placebo-controlled study to evaluate the effects of HIRREM, compared to placebo, for athletes with concussion who experience symptoms persisting longer than 4 weeks following the TBI/concussion. This study will assess the effect of HIRREM on overall post-concussion symptoms, with a focus on headache, sleep, depression, clarity/focus, and balance. Outcome measures will also include pre- and post-intervention blood pressure and heart rate recordings to evaluate autonomic cardiovascular control, brain MRI scans for network connectivity, and blood and saliva biomarkers for stress and inflammation. The study is funded by a research grant from the Susanne Marcus Collins Foundation, Inc.

HIRREM for civilian PTSD/traumatic stress

This project will be designed as a single site, randomized, single blind, placebo-controlled research study to evaluate the effects of HIRREM, compared to placebo, for symptoms of traumatic stress in civilians with a diagnosis of PTSD or symptoms of traumatic stress. Outcome measures will also include pre- and post-intervention blood pressure and heart rate recordings to evaluate autonomic cardiovascular control, brain MRI scans for network connectivity, and a panel of blood and saliva biomarkers for stress and inflammation. This study is funded by a research grant from the Susanne Marcus Collins Foundation, Inc.  

HIRREM for hot flashes

This potential project will be designed as a single site, randomized, single blind, placebo-controlled research study to evaluate the effect of HIRREM, compared to placebo, on the frequency and severity of hot flashes in post-menopausal women. Additional outcome measures will include pre- and post-intervention blood pressure and heart rate recordings to evaluate autonomic cardiovascular control. 

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Last Updated: 04-14-2015
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