Mouse and Rat Microsurgical Techniques Workshop


Course 1
Wednesday - Friday (September 18-20, 2013)    REGISTRATION IS CLOSED

Monday - Wednesday (September 23-25, 2013)     REGISTRATION IS CLOSED 

Please see the agenda for more details. If you have any questions, please contact Dr. Tom Smith at  (336) 716-2093 or e-mail


The advent of modern molecular techniques has resulted in a tremendous explosion of new information concerning the cellular and molecular nature of disease processes. With this surge of information, training in biological sciences has naturally shifted towards these areas. The challenge now facing biomedical scientists is to translate this raw information into valuable insights into the interactions between genetic, environmental, physiologic and disease processes in organ systems or whole animals. Currently, few scientists have training in instrumentation methods which will permit examination of these complex systems.

The Mouse & Rat Microsurgical Techniques Workshop arose from long standing collaborations between Dr. Thomas Smith and Michael Callahan, Transonic Systems Inc. and Millar Instruments. Their ongoing aim is to develop instrumentation for acute and chronic hemodynamic measurements in small animals. These two companies are known for producing instruments which are the "gold standard" in blood flow and pressure respectively. Over the past several years Millar and Transonics have worked to miniaturize their products to permit investigators to take advantage of the tremendous explosion of information concerning new genetic models. 

ADInstruments is proud to support this educational event at Wake Forest.  ADInstruments is a leading developer of data acquisition hardware and software solutions for life science research.  The PowerLab system enables simultaneous real time data recording, analysis and reporting. The success of these companies means that scientists can now perform complex hemodynamic measurements in genetically altered rats and mice both acutely and chronically.

The goal of this course is to introduce scientists to a number of techniques which will enable them to examine complex physiological responses. The course will focus on the surgical skills, techniques and "tricks" which permit acute and chronic instrumentation in small animals. The course will also expose participants to powerful data collection and analysis software designed to facilitate study of these complex physiological systems.

Participants will have an individual workstations with surgical instruments and a microscope.

A number of workstations will have complete data gathering capability.  All participants will be able to acquire data and take a version of software with them that will replay the acquired data.

Workbooks and CDs of all surgical procedures will be provided.

Target Audience

This course is designed for research investigators and technicians who would like to develop surgical skills in acute and chronic instrumentation in small rodents.


At the conclusion of this workshop, the participant will be better able to:

  • Isolate and catheterize small blood vessels (200µm)
  • Place flow probes on small blood vessels.
  • Catheterize small arteries and veins
  • Intubate small rodents and maintain respiratory support
  • Provide pre and post operative care to small rodents
  • Describe integrative approaches to complex hemodynamic monitoring

Special Needs

Wake Forest University Health Sciences adheres to the American with Disabilities Act. Please report any special needs that you may have for participation in and/or accessing this educational workshop to Jan Kelly in the Orthopaedic Research Dept. at (336)716-3950.


A block of rooms has been reserved for this conference at The Hawthorne Inn & Conference Center ($75 + tax – includes breakfast). Please call to make your reservation at (336) 777-3000 or 1-800-972-3774 and identify yourself as a Mouse course participant. (Directions to the course will be sent to you along with your confirmation of registration.)

The Hawthorne Inn & Conference Center
420 High Street
Winston-Salem NC 27101
(336) 777-3000
(877) 777-3099 (toll free)
(336) 777-3144 Fax


The closest airport is Piedmont Triad International, Greensboro, NC. Taxis are available from the airport. Alternatively, the following shuttle services are available:

 PTI Airport Transportation (PTI) 

(877) 796-5466
$63.00 taxi, $3.00 each additional person
Shuttle van $51 per person from Greensboro to "hospital, school or campus"

Piedmont Executive Transportation, Inc.

(336) 661-1100 or email
Black limo sedan: $65 for one person or $32.50 each for 2 people.  A third person would also pay $32.50 to Winston-Salem
Van:  $75 for up to 10 people to Winston-Salem

Raleigh, Durham or Charlotte airports are about 1.5 hour drive and further details about traveling from these airports are available on request.


Mouse & Rat Microsurgical Techniques Workshop Agenda - Course 1 | Course 2 


Please register early to avoid disappointment as spaces are limited. The registration fee will cover all workshop materials, parking, lunches and breaks. If you do not receive registration confirmation within 2 weeks, please call (336) 716-3950 to confirm your registration.

Registration Form

Please do not book travel arrangements before receiving confirmation of your registration. 










For additional information, please call Eileen Martin at (336) 716-3950.


Major Corporate Sponsors:

Transonic Systems Inc.
34 Dutch Mill Rd.
Ithaca, NY 14850

Millar Instruments
6001 A Gulf Freeway
Houston, TX, 77023-5417

ADInstruments, Inc.
2205 Executive Circle
Colorado Springs, CO  80906

Minor Corporate Sponsors:

Charles River Laboratories
251 Ballardvale Street
Wilmington, MA  01887-1000

Other Useful Links

Dragonfly R&D
P.O Box 507
Ridgely, WV 26753-0507

Quick Reference

Orthopaedic Surgery

Research Office
FAX 336-716-7310

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