Mouse and Rat Microsurgical Techniques Workshop
Course 1
Wednesday - Friday (August 25-27, 2010) THIS COURSE IS NOW FILLED
Course 2 -
Monday - Wednesday (August 30 - September 1, 2010) THIS COURSE IS NOW FILLED
Please see the agenda for more details. If you have any questions, please contact Michael Callahan at (336) 716-8901 or e-mail callahan@wakehealth.edu
Introduction
The advent of modern molecular techniques has resulted in a tremendous explosion of new information concerning the cellular and molecular nature of disease processes. With this surge of information, training in biological sciences has naturally shifted towards these areas. The challenge now facing biomedical scientists is to translate this raw information into valuable insights into the interactions between genetic, environmental, physiologic and disease processes in organ systems or whole animals. Currently, few scientists have training in instrumentation methods which will permit examination of these complex systems.
The Mouse & Rat Microsurgical Techniques Workshop arose from long standing collaborations between Drs. Thomas Smith and Michael Callahan, Transonic Systems Inc. and Millar Instruments. Their ongoing aim is to develop instrumentation for acute and chronic hemodynamic measurements in small animals. These two companies are known for producing instruments which are the "gold standard" in blood flow and pressure respectively. Over the past several years Millar and Transonics have worked to miniaturize their products to permit investigators to take advantage of the tremendous explosion of information concerning new genetic models. Millar and Telemetry Research have combined to introduce the world's first fulling implantable transmitter to provide high fidelity measurement of blood pressure in rat sized models. The TRM system combines Millar's pressure accuracy with the extended range and recharging capability of the Telemetry Research platform. In addition, the Telemetry Research products can provide a variety of other signals including SNA, ECG, EMG and EEG. ADInstruments is proud to support this educational event at Wake Forest. ADInstruments is a leading developer of data acquisition hardware and software solutions for life science research. The PowerLab system enables simultaneous real time data recording, analysis and reporting. The success of these companies means that scientists can now perform complex hemodynamic measurements in genetically altered rats and mice both acutely and chronically.
The goal of this course is to introduce scientists to a number of techniques which will enable them to examine complex physiological responses. The course will focus on the surgical skills, techniques and "tricks" which permit acute and chronic instrumentation in small animals. The course will also expose participants to powerful data collection and analysis software designed to facilitate study of these complex physiological systems.
Each participant will have an individual workstation with surgical instruments and a microscope.
A number of workstations will have complete data gathering capability. All participants will be able to acquire data and take a version of software with them that will replay the acquired data.
Workbooks and CDs of all surgical procedures will be provided.
Target Audience
This course is designed for research investigators and technicians who would like to develop surgical skills in acute and chronic instrumentation in small rodents.
Objectives
At the conclusion of this workshop, the participant will be better able to:
- Isolate and catheterize small blood vessels (200µm)
- Place flow probes on small blood vessels.
- Catheterize small arteries and veins
- Intubate small rodents and maintain respiratory support
- Provide pre and post operative care to small rodents
- Describe integrative approaches to complex hemodynamic monitoring
Special Needs
Wake Forest University Health Sciences adheres to the American with Disabilities Act. Please report any special needs that you may have for participation in and/or accessing this educational workshop to Jan Kelly in the Orthopaedic Research Dept. at (336)716-3950.
Accommodations
A block of rooms has been reserved for this conference at The Hawthorne Inn & Conference Center ($75 + tax – includes breakfast). Please call to make your reservation at (336) 777-3000 or 1-800-972-3774 and identify yourself as a Mouse course participant. (Directions to the course will be sent to you along with your confirmation of registration.)
The Hawthorne Inn & Conference Center
420 High Street
Winston-Salem NC 27101
(336) 777-3000
(877) 777-3099 (toll free)
(336) 777-3144 Fax
http://hawthorneinn.com
Transport
The closest airport is Piedmont Triad International, Greensboro, NC. Taxis are available from the airport. Alternatively, the following shuttle services are available:
Raleigh, Durham or Charlotte airports are about 1.5 hour drive and further details about traveling from these airports are available on request.
Agenda
Mouse & Rat Microsurgical Techniques Workshop Agenda - Course 1 | Course 2
Registration
Please register early to avoid disappointment as spaces are limited. The registration fee will cover all workshop materials, parking, lunches and breaks. If you do not receive registration confirmation within 2 weeks, please call (336) 716-3950 to confirm your registration.
Registration Form
| Please do not book travel arrangements before receiving confirmation of your registration. |
Information
For additional information, please call Eileen Martin at (336) 716-3950.
Sponsors
Major Corporate Sponsors:
Minor Corporate Sponsors:
Other Useful Links
Animal Care Systems
Michael O’Connor
805 Vestavia Woods Drive
Raleigh, NC 27615
Business: (919) 846-1304
Mobile: (919) 741-8577
e-mail: moconnor@animalcaresystems.com
Dragonfly R&D
P.O Box 507
Ridgely, WV 26753-0507
www.Dragonflyinc.com
Data Sciences International
4211 Lexington Avenue N
Suite 2244,
St Paul, MN 55126
www.datasci.com/index.php
EMKA Technologies
115 Hillwood Avenue, Suite 203
Falls Church, VA 22046
Tel: +1 (703) 237-9001
Fax: +1 (703) 237-9006
e-mail: mailto:emkatech.com@emkatech.com
www.emkatech.com