Christine N. McMahan, BS

Laboratory Technician IV / Lab Manager

Lab Phone  336-713-7626


University of West Georgia
B.S., Biology

Research Interests:

Tie2 is an endothelial receptor tyrosine kinase that plays an important role in angiogenesis and vessel stabilization.  Tie2 is often overexpressed on the vasculature of breast and other cancers, and its inhibition can prevent tumor growth.  My current studies focus on the mechanism of regulation of endothelial Tie2 expression by tumor cells, mural cells, and the cytokine Vascular Endothelial Growth Inhibitor (VEGI).  In addition, we are investigating the mechanism by which stimulation of Tie2 by its Angiopoietin-1 ligand stabilizes blood vessels.


Last Updated: 01-06-2015
USNWR 2015-2016Magnet Hospital RecognitionConsumer Choice2014 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.