Rheumatology Research

Research in Rheumatology

The research interests of the faculty are broad and include clinical research in interventional rheumatology such as arthroscopy, rheumatoid arthritis, osteoarthritis, systemic lupus erythematosus (SLE), Sjogren's syndrome, and Raynaud's syndrome. 

Basic research studies of the faculty include molecular mechanisms of cellular immune dysfunction in SLE, signal transduction in B cells, and the control of macrophage functions in inflammation. The laboratory of Dr. Wallin has developed a system to study the molecular mechanisms of the anti-coagulant Coumadin and is currently isolating the Coumadin-sensitive enzyme present in the vitamin K cycle with a goal of creating better anticoagulant drugs and revealing the molecular cause of Coumadin resistance.

Research Highlights

Research Studies Suggest Targeted Treatment Strategies for Lupus 

Existing Drugs Show Promise for Treating End-Stage Renal Disease in Lupus 

New Biomarkers for Lupus Found

Common Anti-seizure Drug Could Be Effective for Lupus Patients 

Cancer Drug May Reduce Kidney Disease in Lupus

Last Updated: 09-09-2014
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