Paul Gatenholm, PhD
Paul Gatenholm, PhD, Adjunct Professor
Dr. Gatenholm is Professor of Biopolymer Technology at Chalmers University of Technology in Sweden and has been Adjunct Professor of Biomaterials at the School of Biomedical Engineering and Sciences at Virginia Polytechnic Institute and State University since 2009. Dr. Gatenholm is a material scientist with interest in biomimetic biomaterials for tissue replacement and regeneration.
SYNOPSIS OF AREA OF INTEREST: 3D Bioprinting - development of new bioinks, novel biomaterials based on polysaccharides, biomimetic scaffolds for tissue engineering, bacterial-cellulose for blood vessel replacement. Biomaterials which induce healing process, soft tissue and particularly cartilage regeneration.
DETAILED AREA OF INTEREST: Biological materials are superior to man-made synthetic materials with regard to combination of mechanical properties such as stiffness and impact strength yet exhibit very light weight. They are also highly anisotropic and self-repairing. They are produced without the use of solvents and with low energy consumption. In biological systems, advanced micro-architecture is assembled with precise control of size and structures. Dr. Gatenholm’s research aims at the biomimetic design of future materials. This includes understanding of structure-property relationship and requires use of advanced material characterization methods which can be applied in wet state and will provide information at all length scales.
Dr. Gatenholm has studied the structure and unique properties of biological materials such as bone, wood, cartilage, jelly-fish and shells. He uses the principle of biomimetic design for preparation of new materials using renewable building blocks. His research includes biological fabrication which includes use of enzymes, cells and coordination of system biology. Dr. Gatenholm is particularly interested in designing and preparing biomaterials which can replace or regenerate tissue and organs. He has been working closely with cardiovascular surgeons to developed technology to produce small calibre blood vessels. He uses bacteria to spin nanocellulose fibrils which are assembled into robust biocompatible materials. This bacterial cellulose blood vessel project is in translation into clinic. Dr. Gatenholm has also been working with orthopaedic surgeons to develop scaffolds to grow cartilage for ear and meniscus repair. He has recently started developed novel polysaccharide bioinks for 3D Bioprinting. These bioinks are in translation as CELLINKTM. Dr. Gatenholm established recently the 3D Bioprinting Center at Chalmers in Sweden which has initiated several preclinical projects. He has published more than 300 papers and edited several books and has more than 6000 citations. He is elected member of Swedish Royal Academy of Engineering Sciences.