Faculty Publications 2008 - Present

Lay-language summaries are available for some publications. Look for the "READ A SUMMARY" notation.

Acta Biomaterials
Bilayered constructs aimed at osteochondral strategies: The influence of medium supplements in the osteogenic and chondrogenic differentiation of amniotic fluid-derived stem cells. Rodrigues MT, Lee SJ, Gomes ME, Reis RL, Atala A, Yoo JJ. Acta Biomater. 2012 Apr 14. [Epub ahead of print]

Controlled heparin conjugation on electrospun poly(ε-caprolactone)/gelatin fibers for morphology-dependent protein delivery and enhanced cellular affinity. Lee J, Yoo JJ, Atala A, Lee SJ. Acta Biomater. 2012 Mar 28. [Epub ahead of print]

Acta Dermato-Venereologica
In vitro and in vivo characterization of a novel liposomal butorphanol formulation for treatment of pruritus. Lim GJ, Ishiuji Y, Dawn A, Harrison B, Kim do W, Atala A, Yosipovitch G. Acta Derm Venereol.  2008;88(4):327-30.

Advances in Experimental Medicine and Biology
Cell microencapsulation. Lim GJ, Zare S, Van Dyke M, Atala A. Adv Exp Med Biol. 2010;670:126-36. Review.

Alcoholism: Clinical and Experimental Research
Ethanol alters the osteogenic differentiation of amniotic fluid-derived stem cells.Hipp JA, Hipp JD, Atala A, Soker S. Alcohol Clin Exp Res. 2010 Oct;34(10):1714-22. doi: 10.1111/j.1530-0277.2010.01258.x. Epub 2010 Jul 5.

American Journal of Pathology
Compression-induced muscle injury in rats that mimics compartment syndrome in humans.Criswell TL, Corona BT, Ward CL, Miller M, Patel M, Wang Z, Christ GJ, Soker S.Am J Pathol. 2012 Feb;180(2):787-97. Epub 2011 Nov 28.

American Journal of Physical Medicine and Rehabilitation
Testosterone replacement therapy and motor function in men with spinal cord injury: a retrospective analysis. Clark MJ, Petroski GF, Mazurek MO, Hagglund KJ, Sherman AK, Lammy AB, Childers MK, Acuff ME. Am J Phys Med Rehabil. 2008 Apr;87(4):281-4.

American Journal of Physiology - Renal Physiology
Impact of partial urethral obstruction on bladder function: Time-dependent changes and functional correlates of altered expression of Ca2+ signaling regulators.Burmeister D, Aboushwareb T, D'Agostino R Jr, Andersson KE, Christ GJ.Am J Physiol Renal Physiol. 2012 Mar 21. [Epub ahead of print]

Annals of Biomedical Engineering
Bioreactors for development of tissue engineered heart valves.Berry JL, Steen JA, Koudy Williams J, Jordan JE, Atala A, Yoo JJ.Ann Biomed Eng. 2010 Nov;38(11):3272-9. Epub 2010 Sep 4. Review.

Annals of Surgery
Regenerative medicine as applied to general surgery. Orlando G, Wood KJ, De Coppi P, Baptista PM, Binder KW, Bitar KN, Breuer C, Burnett L, Christ G, Farney A, Figliuzzi M, Holmes JH 4th, Koch K, Macchiarini P, Mirmalek Sani SH, Opara E, Remuzzi A, Rogers J, Saul JM, Seliktar D, Shapira-Schweitzer K, Smith T, Solomon D, Van Dyke M, Yoo JJ, Zhang Y, Atala A, Stratta RJ, Soker S. Ann Surg. 2012 May;255(5):867-80

Archives of Pharmacal Research
Amniotic fluid-derived stem cells in regenerative medicine research. Joo S, Ko IK, Atala A, Yoo JJ, Lee SJ. Arch Pharm Res. 2012 Feb;35(2):271-80. Epub 2012 Feb 28.

Archives of Sexual Behavior
Aggressive and mating behaviors in two types of sex reversed mice: XY females and XX males. Canastar A, Maxson SC, Bishop CE. Arch Sex Behav. 2008 Feb;37(1):2-8.

Biology of Reproduction
A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice. Lu B, Poirier C, Gaspar T, Gratzke C, Harrison W, Busija D, Matzuk MM, Andersson KE, Overbeek PA, Bishop CE. Biol Reprod. 2008 Apr;78(4):601-10. Epub 2007 Dec 19.

Engineered cartilage covered ear implants for auricular cartilage reconstruction. Lee SJ, Broda C, Atala A, Yoo JJ. Biomacromolecules. 2011 Feb 14;12(2):306-13. Epub 2010 Dec 23.

● Cytokine combination therapy prediction for bone healing and bone remodeling based on the intracellular signaling pathway. Sun XQ, Su J, Peng T, Zhang L, Bao JG, Zhang Y (Co-responding author), Yang YZ, Zhou XB. Biomaterials 2012 (IF 7.4, On line).

Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function. Skardal A, Smith L, Bharadwaj S, Atala A, Soker S, Zhang Y. Biomaterials. 2012 Jun;33(18):4565-75. Epub 2012 Apr 2.

 Co-electrospun dual scaffolding system with potential for muscle-tendon junction tissue engineering. Ladd, M.R., Lee, S.J., Stitzel, J.D., Atala, A., Yoo, J.J., Biomaterials  2011,32 (6), 1549-59.

 Human urine-derived stem cells seeded in a modified 3D porous small intestinal submucosa scaffold for urethral tissue engineering, Wu, S., Liu, Y., Bharadwaj, S., Atala, A., Zhang, Y. Biomaterials 2011, 32 (5), 1317-26.

Three-dimensional culture of hepatocytes on porcine liver tissue-derived extracellular matrix. Lang R, Stern MM, Smith L, Liu Y, Bharadwaj S, Liu G, Baptista PM, Bergman CR, Soker S, Yoo JJ, Atala A, Zhang Y. Biomaterials. 2011 Oct;32(29):7042-52. Epub 2011 Jul 1.

 Tissue-engineered conduit using urine-derived stem cells seeded bacterial cellulose polymer in urinary reconstruction and diversion ,  Bodin, A., Bharadwaj, S., Wu, S., Gatenholm, P., Atala, A., Zhang, Y. Biomaterials , 2010, 31 (34), 8889-8901.

 Bioengineering endothelialized neo-corneas using donor-derived corneal endothelial cells and decellularized corneal stroma. Choi, J.S., Williams, J.K., Greven, M., Walter, K.A., Laber, P.W., Khang, G., Soker, S. Biomaterials 2010, 31 (26), 6738-45.

 Bilayered scaffold for engineering cellularized blood vessels, Ju, Y.M., Choi, J.S., Atala, A., Yoo, J.J., Lee, S.J. Biomaterials 2010, 31 (15), 4313-21.

 The effect of FGF-1 loaded alginate microbeads on neovascularization and adipogenesis in a vascular pedicle model of adipose tissue engineering. Moya, M.L., Cheng, M.-H., Huang, J.-J., Francis-Sedlak, M.E., Kao, S.-w., Opara, E.C., Brey, E.M. Biomaterials 2010, 31 (10), 2816-26.

 Myogenic differentiation of human bone marrow mesenchymal stem cells on a 3D nano fibrous scaffold for bladder tissue engineering. Tian, H., Bharadwaj, S., Liu, Y., Ma, H., Ma, P.X., Atala, A., Zhang, Y. Biomaterials 2010, 31 (5), 870-7.

 Some properties of keratin biomaterials: Kerateines. Hill, P., Brantley, H., Van Dyke, M. Biomaterials 2010. 31 (4), 585-93.

 On the nature of biomaterials , Williams, D.F. Biomaterials 2009, 30 (30), 5897-909.

Optimization of a natural collagen scaffold to aid cell-matrix penetration for urologic tissue engineering, Liu, Y., Bharadwaj, S., Lee, S.J., Atala, A., Zhang, Y. Biomaterials 2009, 30 (23-24), 3865-73.

  Tissue-specific extracellular matrix coatings for the promotion of cell proliferation and maintenance of cell phenotype . Zhang, Y., He, Y., Bharadwaj, S., Hammam, N., Carnagey, K., Myers, R., Atala, A., Van Dyke, M. Biomaterials 2009, 30 (23-24),  4021-28

 The influence of extracellular matrix derived from skeletal muscle tissue on the proliferation and differentiation of myogenic progenitor cells ex vivo . Stern, M.M., Myers, R.L., Hammam, N., Stern, K.A., Eberli, D., Kritchevsky, S.B., Soker, S., Van Dyke, M. Biomaterials 2009, 30 (12), 2393-99.

 The in vivo stability of electrospun polycaprolactone-collagen scaffolds in vascular reconstruction, Tillman, B.W., Yazdani, S.K., Lee, S.J., Geary, R.L., Atala, A., Yoo, J.J.  Biomaterials 2009, 30 (4), 583-8.

 Oxygen generating scaffolds for enhancing engineered tissue survival, Oh, S.H., Ward, C.L., Atala, A., Yoo, J.J., Harrison, B.S. Biomaterials 2009, 30 (5), 757-62.

 The influence of extracellular matrix derived from skeletal muscle tissue on the proliferation and differentiation of myogenic progenitor cells ex vivo . Stern, M.M., Myers, R.L., Hamman, N., Stern, K.A., Eberle, D., Kritchevsky, S.B., Soker, S., Van Dyke, M. Biomaterials, 2009, 30(12), 2393-9.

 Development of a composite vascular scaffolding system that withstands physiological vascular conditions , Lee, S.J., Liu, J., Oh, S.H., Soker, S., Atala, A., Yoo, J.J. Biomaterials 2008, 29 (19), 2891-8

The influence of electrospun aligned poly(ε-caprolactone)/collagen nanofiber meshes on the formation of self-aligned skeletal muscle myotubes. Choi, J.S., Lee, S.J., Christ, G.J., Atala, A., Yoo, J.J. Biomaterials 2008, 29 (19), 2899-906

 The use of thermal treatments to enhance the mechanical properties of electrospun poly(ε-caprolactone) scaffolds, Lee, S.J., Oh, S.H., Liu, J., Soker, S., Atala, A., Yoo, J.J. Biomaterials 2008, 29 (10),  1422-30

 The use of keratin biomaterials derived from human hair for the promotion of rapid regeneration of peripheral nerves, Sierpinski, P., Garrett, J., Ma, J., Apel, P., Klorig, D., Smith, T., Koman, L.A., Atala A, Van Dyke, M. Biomaterials 2008, 29 (1), 11-128.

 On the mechanisms of biocompatibility , Williams, D.F. Biomaterials 2008, 29 (20), 2941-53. 

 British Medical Bulletin
Tissue engineering of human bladder. Atala A. Br Med Bull. 2011;97:81-104. Epub 2011 Feb 15. Review

British Journal of Urology International
 Signal transduction pathways of muscarinic receptor mediated activation in the newborn and adult mouse urinary bladder. Ekman M, Andersson KE, Arner A. BJU Int. 2009 Jan;103(1):90-7.

A canine model of irreversible urethral sphincter insufficiency. Eberli D, Andersson KE, Yoo JJ, Atala A. BJU Int. 2008 Sep 8. [Epub ahead of print]

Microarray analysis of bladder smooth muscle from patients with myelomeningocele. Hipp JA, Hipp JD, Yoo JJ, Atala A, Andersson KE. BJU Int. 2008 Sep;102(6):741-6. Epub 2008 Mar 11.

Angiogenic gene modification of skeletal muscle cells to compensate for ageing-induced decline in bioengineered functional muscle tissue. Delo DM, Eberli D, Williams JK, Andersson KE, Atala A, Soker S. BJU Int. 2008 Sep;102(7):878-84. Epub 2008 May 16.   READ A SUMMARY  
Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivo. Ney P, Pandita RK, Newgreen DT, Breidenbach A, Stöhr T, Andersson KE. BJU Int. 2008 Apr;101(8):1036-42. Epub 2008 Feb 15.

Microarray analysis of exstrophic human bladder smooth muscle. Hipp J, Andersson KE, Kwon TG, Kwak EK, Yoo J, Atala A. BJU Int. 2008 Jan;101(1):100-5. Epub 2007 Sep 13.

Cancer Gene Therapy
Expression-targeted gene therapy for the treatment of transitional cell carcinoma. Zhang X, Atala A, Godbey WT. Cancer Gene Ther. 2008 Aug;15(8):543-52. Epub 2008 Mar 7.

Cancer Research
The role of the mouse Y chromosome on susceptibility to testicular germ cell tumors. Anderson P.D., Lam M-Y., Poirier C., Bishop C.E. and Nadeau J.H. Cancer Research. 2009 (In Press)

 Cardiovascular Pathology
Calcification after myocardial infarction is independent of amniotic fluid stem cell injection. Delo DM, Guan X, Wang Z, Groban L, Callahan M, Smith T, Sane DC, Payne RM, Atala A, Soker S. Cardiovasc Pathol. 2010 Apr 8.

Cell Transplantation
Muscle Precursor Cells for the Restoration of Irreversibly Damaged Sphincter Function. Eberli D, Aboushwareb T, Soker S, Yoo JJ, Atala A. Cell Transplant. 2012 Jan 10. [Epub ahead of print]

Cloning and Stem Cells
Reprogramming of Human Somatic Cells Using Human and Animal Oocytes. Chung Y, Bishop CE, Treff NR, Walker SJ, Sandler VM, Becker S, Klimanskaya I, Wun WS, Dunn R, Hall RM, Su J, Lu SJ, Maserati M, Choi YH, Scott R, Atala A, Dittman R, Lanza R. Cloning Stem Cells. 2009 Feb 2. [Epub ahead of print]

Chonnam Medical Journal
Tissue engineering: current strategies and future directions. Olson JL, Atala A, Yoo JJ. Chonnam Med J. 2011 Apr;47(1):1-13. Epub 2011 Apr 26.

Current Genomics
Functional genomics: new insights into the 'function' of low levels of gene expression in stem cells. Hipp JA, Hipp JD, Atala A, Soker S. Curr Genomics. 2010 Aug;11(5):354-8.

Current Stem Cell Research and Therapy
Editorial: effective bio-economic approaches for stem cell therapy and regenerative medicine. Mhashilkar A, Atala A. Curr Stem Cell Res Ther. 2012 Jan 1;7(1):1. No abstract available.

New frontiers in stem cell research and therapy. Atala A. Curr Stem Cell Res Ther. 2009 Jan;4(1):1. No abstract available.

Advances in tissue and organ replacement. Atala A. Curr Stem Cell Res Ther. 2008 Jan;3(1):21-31. Review.

Current Urology Reports
A randomized placebo-controlled study of the efficacy of antimuscarinics in the treatment of pediatric overactive bladder and incontinence. Hodges SJ, Atala A. Curr Urol Rep. 2009 Jan;10(1):6-7. No abstract available.

Urothelial effects of oral agents for overactive bladder. Andersson KE, Fullhase C, Soler R. Curr Urol Rep. 2008 Nov;9(6):459-64.

Producing organs in the laboratory. Furth ME, Atala A. Curr Urol Rep. 2008 Nov;9(6):433-6. No abstract available.

Experimental Hematology
Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC.Porada CD, Sanada C, Kuo CJ, Colletti E, Mandeville W, Hasenau J, Zanjani ED, Moot R, Doering C, Spencer HT, Almeida-Porada G.Exp Hematol. 2011 Dec;39(12):1124-1135.e4. doi: 10.1016/j.exphem.2011.09.001. Epub 2011 Sep 8

European Urology
● Cell-Seeded Tubularized Scaffolds for Reconstruction of Long Urethral Defects: A Preclinical Study.   Orabi H, Aboushwareb T, Zhang Y, Yoo JJ, Atala A. Eur Urol. 2012 Jul 31. (IF 8.5, Online)

Localization and Function of Cannabinoid Receptors in the Corpus Cavernosum: Basis for Modulation of Nitric Oxide Synthase Nerve Activity. Gratzke C, Christ GJ, Stief CG, Andersson KE, Hedlund P. Eur Urol. 2009 Jan 3. [Epub ahead of print]

Smooth-Muscle-Specific Gene Transfer with the Human Maxi-K Channel Improves Erectile Function and Enhances Sexual Behavior in Atherosclerotic Cynomolgus Monkeys. Christ GJ, Andersson KE, Williams K, Zhao W, D'Agostino R Jr, Kaplan J, Aboushwareb T, Yoo J, Calenda G, Davies KP, Sellers RS, Melman A. Eur Urol. 2008 Dec 25. [Epub ahead of print]

Transient Receptor Potential A1 (TRPA1) Activity in the Human Urethra-Evidence for a Functional Role for TRPA1 in the Outflow Region. Gratzke C, Streng T, Waldkirch E, Sigl K, Stief C, Andersson KE, Hedlund P. Eur Urol. 2008 Apr 30. [Epub ahead of print]

Distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder. Streng T, Axelsson HE, Hedlund P, Andersson DA, Jordt SE, Bevan S, Andersson KE, Högestätt ED, Zygmunt PM. Eur Urol. 2008 Feb;53(2):391-9. Epub 2007 Oct 22.

The Federation of American Societies for Experimental Biology Journal
Combined systemic and local delivery of stem cell inducing/recruiting factors for in situ tissue regeneration. Ko IK, Ju YM, Chen T, Atala A, Yoo JJ, Lee SJ. FASEB J. 2012 Jan;26(1):158-68. Epub 2011 Sep 30. Erratum in: FASEB J. 2012 Mar;26(3):1360. 

Fertility and Sterility
Oocyte-specific G-protein-coupled receptor 3 (GPR3): no perturbations found in 82 women with premature ovarian failure (first report). Kovanci E, Simpson JL, Amato P, Rohozinski J, Heard MJ, Bishop CE, Carson SA. Fertil Steril. 2008 Oct;90(4):1269-71. Epub 2007 Oct 22.

Gene Therapy
Gene transfer with a vector expressing Maxi-K from a smooth muscle-specific promoter restores erectile function in the aging rat. Melman A, Biggs G, Davies K, Zhao W, Tar MT, Christ GJ. Gene Ther. 2008 Mar;15(5):364-70. Epub 2008 Jan 17.

Cell and organ bioengineering technology as applied to gastrointestinal diseases. Orlando G, Bendala JD, Shupe T, Bergman C, Bitar KN, Booth C, Carbone M, Koch KL, Lerut JP, Neuberger JM, Petersen B, Ricordi C, Atala A, Stratta RJ, Soker S. Gut. 2012 Jan 20. [Epub ahead of print] 

The use of whole organ decellularization for the generation of a vascularized liver organoid.Baptista PM, Siddiqui MM, Lozier G, Rodriguez SR, Atala A, Soker S.Hepatology. 2011 Feb;53(2):604-17. doi: 10.1002/hep.24067. Epub 2011 Jan 10. 

Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model. Wood JA, Colletti E, Mead LE, Ingram D, Porada CD, Zanjani ED, Yoder MC, Almeida-Porada G. Hepatology. 2012 Apr 4. doi: 10.1002/hep.25753. [Epub ahead of print]

IEEE Engineering in Medicine and Biology Society (Conference Proceedings)
Whole organ decellularization - a tool for bioscaffold fabrication and organ bioengineering. Baptista PM, Orlando G, Mirmalek-Sani SH, Siddiqui M, Atala A, Soker S. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6526-9.

International Journal of Impotence Research
Animal models of erectile dysfunction (ED): potential utility of non-human primates as a model of atherosclerosis-induced vascular ED. Williams JK, Andersson KE, Christ G.Int J Impot Res. 2012 May;24(3):91-100. doi: 10.1038/ijir.2011.56. Epub 2011 Dec 29.

International Neurourology Journal
Regenerative medicine strategies for treating neurogenic bladder. Yoo JJ, Olson J, Atala A, Kim B. Int Neurourol J. 2011 Sep;15(3):109-19. Epub 2011 Sep 30.

Journal of Biomedical Materials Research Part A

● New ureteral scaffold constructed with composite poly(L-lactic acid)-collagen and urothelial cells by new centrifugal seeding system. Fu WJ, Xu JD, Wang ZW, Li G, Cui FZ, Zhang Y and Zhang X. J Biomed  Mater Res Part 2012 Jul;100(7):1725-33. (IF 3.044)

In vivo evaluation of acellular human dermis for abdominal wall repair. Eberli D, Rodriguez S, Atala A, Yoo JJ. J Biomed Mater Res A. 2010 Jun 15;93(4):1527-38.

Journal of Biomedical Materials Research Part B: Applied Biomaterials
A keratin biomaterial gel hemostat derived from human hair: Evaluation in a rabbit model of lethal liver injury. Aboushwareb T, Eberli D, Ward C, Broda C, Holcomb J, Atala A, Van Dyke M. J Biomed Mater Res B Appl Biomater., 2008 Nov 5. [Epub ahead of print]

Journal of Cellular Biochemistry
Stem cell sources to treat diabetes. Furth ME, Atala A. J Cell Biochem. 2009 Jan 7. [Epub ahead of print]

Journal of Gene Medicine
Expression levels of the PiT-2 receptor explain, in part, the gestational age-dependent alterations in transduction efficiency after in utero retroviral-mediated gene transfer.Ozturk F, Park PJ, Tellez J, Colletti E, Eiden MV, Almeida-Porada G, Porada CD. J Gene Med. 2012 Mar;14(3):169-81. doi: 0.1002/jgm.2607.

Journal of Material Science: Materials in Medicine
One and four layer acellular bladder matrix for fascial tissue reconstruction. Eberli D, Atala A, Yoo JJ. J Mater Sci Mater Med. 2011 Mar;22(3):741-51. Epub 2011 Feb 1.

Journal of Hand Surgery
Peripheral nerve regeneration using a keratin-based scaffold: long-term functional and histological outcomes in a mouse model. Apel PJ, Garrett JP, Sierpinski P, Ma J, Atala A, Smith TL, Koman LA, Van Dyke ME. J Hand Surg [Am]. 2008 Nov;33(9):1541-7.

Journal of Investigative Medicine
Regenerative medicine: basic concepts, current status, and future applications.Corona BT, Ward CL, Harrison BS, Christ GJ. J Investig Med. 2010 Oct;58(7):849-58.

Journal of Pediatric Surgery
Regenerative medicine strategies. Atala A. J Pediatr Surg. 2012 Jan;47(1):17-28.

Journal of Pineal Research
Melatonin restores impaired contractility in aged guinea pig urinary bladder. Gomez-Pinilla PJ, Gomez MF, Swärd K, Hedlund P, Hellstrand P, Camello PJ, Andersson KE, Pozo MJ. J Pineal Res. 2008 May;44(4):416-25. Epub 2008 Jan 9.

Journal of Sexual Medicine

● Long T, Liu GH, Deng CH, Zhang Y* and  DN Qin* ( *Co-corresponding authors). TNF-α contributes to erectile dysfunction by promoting NADPH oxidase-mediated ROS generation in corpus cavernosum in the high fat diet/streptozotocin-induced diabetic rats. J Sex Med 2012 Jul;9(7):1801-14 (IF 4.864).

Glycosylated Serum Protein May Improve Our Ability to Predict Endothelial and Erectile Dysfunction in Nonorganic Patients. Huang Y, Sun X, Liu G, Yao F, Zheng F, Dai Y, Tu X, Xie X, Deng L, Zhang D, Zhang Y, Bian J, Gao Y, Ye Y, Deng C, Zhang Y. J Sex Med. 2010 Dec 8. doi: 10.1111/j.1743-6109.2010.02141. 

 JJournal of Thoracic and Cardiovascular Surgery
Bioengineered self-seeding heart valves. Jordan JE, Williams JK, Lee SJ, Raghavan D, Atala A, Yoo JJ. J Thorac Cardiovasc Surg. 2012 Jan;143(1):201-8. Epub 2011 Nov 1.

Journal of Tissue Engineering and Regenerative Medicine
Engineering functional bladder tissues. Horst M, Madduri S, Gobet R, Sulser T, Milleret V, Hall H, Atala A, Eberli D. J Tissue Eng Regen Med. 2012 Mar 21. doi: 10.1002/term.547. [Epub ahead of print]

In vitro cardiomyogenic potential of human amniotic fluid stem cells. Guan X, Delo DM, Atala A, Soker S. J Tissue Eng Regen Med. 2011 Mar;5(3):220-8. doi: 10.1002/term.308.

Journal of Urology
●   Implantation of autologous urine derived stem cells expressing vascular endothelial growth factor for potential use in genitourinary reconstruction. Wu S, Wang Z, Bharadwaj S, Hodges SJ, Atala A, Zhang Y. J Urol. 2011 Aug;186(2):640-7. Epub 2011 Jun 17.

Spinal effects of the fesoterodine metabolite 5-hydroxymethyl tolterodine and/or doxazosin in rats with or without partial urethral obstruction. Füllhase C, Soler R, Gratzke C, Brodsky M, Christ GJ, Andersson KE. J Urol. 2010 Aug;184(2):783-9. Epub 2010 Jun 19.

Bladder tissue regeneration. Christ GJ. J Urol. 2009 Jul;182(1):16-7. Epub 2009 May 17. No abstract available.

Distribution and Function of Cannabinoid Receptors 1 and 2 in the Rat, Monkey and Human Bladder. Gratzke C, Streng T, Park A, Christ G, Stief CG, Hedlund P, Andersson KE. J Urol. 2009 Feb 21. [Epub ahead of print]

Passing the Torch II. Andersson KE. J Urol. 2009 Jan;181(1):8.

The clinician scientist and medical advances. Atala A. J Urol. 2008 Aug;180(2):431-2. Epub 2008 Jun 11. No abstract available. Erratum in: J Urol. 2008 Dec;180(6):2721.

Urine derived cells are a potential source for urological tissue reconstruction. Zhang Y, McNeill E, Tian H, Soker S, Andersson KE, Yoo JJ, Atala A. J Urol. 2008 Nov;180(5):2226-33.

 Effects of long-term dietary soy treatment on female urethral morphology and function in ovariectomized  nonhuman primates. Gratzke C, Jarajapu YP, Christ GJ, Kaplan JR, Williams JK, Andersson KE, Badlani G. J Urol. 2008 Nov;180(5):2247-53.

 How many drugs for LUTS due to BPH are too many? Andersson KE. J Urol. 2008 Sep;180(3):811-2.

Bladder reconstruction by tissue engineering--with or without cells? Zhang Y. J Urol. 2008 Jul;180(1):392-7.

Voiding pattern analysis as a surrogate for cystometric evaluation in uroplakin II knockout mice. Hodges SJ, Zhou G, Deng FM, Aboushwareb T, Turner C, Andersson KE, Santago P, Case D, Sun TT, Christ GJ. J Urol. 2008 May;179(5):2046-51.

Randomized comparative study between buccal mucosal and acellular bladder matrix grafts in complex anterior urethral strictures. el-Kassaby A, AbouShwareb T, Atala A. J Urol. 2008 Apr;179(4):1432-6. Erratum in: J Urol. 2008 Jun;179(6):2490.   READ A SUMMARY  

Local and systemic effects of a tissue engineered neobladder in a canine cystoplasty model. Kwon TG, Yoo JJ, Atala A. J Urol. 2008 May;179(5):2035-41. Epub 2008 Mar 19. 

 .Human embryonic stem cells: early hints on safety and efficacy. Atala A. Lancet. 2012 Feb 25;379(9817):689-90. Epub 2012 Jan 24. No abstract available.

Tissue-engineered autologous urethras for patients who need reconstruction: an observational study. Raya-Rivera A, Esquiliano DR, Yoo JJ, Lopez-Bayghen E, Soker S, Atala A. Lancet. 2011 Apr 2;377(9772):1175-82

Guest editors' introduction. Methods in tissue engineering. Atala A, Yoo JJ. Methods. 2009 Feb;47(2):79-80. No abstract available.

Composite scaffolds for the engineering of hollow organs and tissues. Eberli D, Freitas Filho L, Atala A, Yoo JJ. Methods. 2009 Feb;47(2):109-15. Epub 2008 Oct 24.

Optimization of human skeletal muscle precursor cell culture and myofiber formation in vitro. Eberli D, Soker S, Atala A, Yoo JJ. Methods. 2009 Feb;47(2):98-103. Epub 2008 Oct 24.

In vitro generation of three-dimensional renal structures. Joraku A, Stern KA, Atala A, Yoo JJ. Methods. 2009 Feb;47(2):129-33. Epub 2008 Oct 7.   READ A SUMMARY  

Parthenogenesis-derived multipotent stem cells adapted for tissue engineering applications. Koh CJ, Delo DM, Lee JW, Siddiqui MM, Lanza RP, Soker S, Yoo JJ, Atala A. Methods. 2009 Feb;47(2):90-7. Epub 2008 Sep 15.   READ A SUMMARY

 Molecular & Cellular Proteomics
Proteomics analysis identifies molecular targets related to diabetes mellitus-associated bladder dysfunction. Yohannes E, Chang J, Christ GJ, Davies KP, Chance MR. Mol Cell Proteomics. 2008 Jul;7(7):1270-85. Epub 2008 Mar 12.

Molecular Interventions
Regenerative pharmacology for diabetes mellitus.Furth ME, Christ GJ.Mol Interv. 2009 Aug;9(4):171-4. No abstract available.

Nature Clinical Practice Urology
Stem cells in urology. Aboushwareb T, Atala A. Nat Clin Pract Urol. 2008 Nov;5(11):621-31.

Are female lower urinary tract symptoms alleviated by alpha-adrenoreceptor antagonists? Andersson KE. Nat Clin Pract Urol. 2008 Nov;5(11):586-7.

Nephrology Dialysis Transplantation
● In vitro reconstitution of human kidney structures for renal cell therapy. Guimaraes-Souza NK, Yamaleyeva LM, Aboushwareb T, Atala A, Yoo JJ. Nephrol Dial Transplant. 2012 Jan 28. [Epub ahead of print]

Neuromuscular Disorders
TCAP knockdown by RNA interference inhibits myoblast differentiation in cultured skeletal muscle cells. Markert CD, Ning J, Staley JT, Heinzke L, Childers CK, Ferreira JA, Brown M, Stoker A, Okamura C, Childers MK. Neuromuscul Disord. 2008 May;18(5):413-22. Epub 2008 Apr 28.

Neurourology and Urodynamics

AlterationsQ1 in Bladder Function Associated With Urothelial Defects in Uroplakin II and III Knockout Mice. Aboushwareb T, Zhou G, Deng FM, Turner C, Andersson KE, Tar M, Zhao W, Melman A, D'Agostino R, Sun T, and Christ GJ. Neurourol Urodyn.2009 26:1-7.

Role of alpha(1)-adrenergic receptors in detrusor overactivity induced by cold stress in conscious rats. Chen Z, Ishizuka O, Imamura T, Aizawa N, Igawa Y, Nishizawa O, Andersson KE. Neurourol Urodyn. 2008 Oct 6. [Epub ahead of print]

Simultaneous registration of intraabdominal and intravesical pressures during cystometry in conscious rats--effects of bladder outlet obstruction and intravesical PGE2. Lee T, Andersson KE, Streng T, Hedlund P. Neurourol Urodyn. 2008;27(1):88-95.

Embryoid body formation of human amniotic fluid stem cells depends on mTOR. Valli A, Rosner M, Fuchs C, Siegel N, Bishop CE, Dolznig H, Mädel U, Feichtinger W, Atala A, Hengstschläger M. Oncogene. 2010 Feb 18;29(7):966-77. Epub 2009 Nov 23.

Pediatric Research
Bioengineered tissues for urogenital repair in children. Atala A. Pediatr Res. 2008 May;63(5):569-75. Review.

Physical Medicine & Rehabilitation
Mesenchymal stem cells: emerging therapy for Duchenne muscular dystrophy. Markert CD, Atala A, Cann JK, Christ G, Furth M, Ambrosio F, Childers MK. PM R. 2009 Jun;1(6):547-59. Review.

Centriole inheritance. Wilson PG. Prion. 2008 Jan;2(1):9-16.

Proceedings of the National Academy of Sciences
Bioengineered corporal tissue for structural and functional restoration of the penis. Chen KL, Eberli D, Yoo JJ, Atala A. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3346-50. Epub 2009 Nov 13.

Rejuvenation Research
Host cell mobilization for in situ tissue regeneration. Lee SJ, Van Dyke M, Atala A, Yoo JJ. Rejuvenation Res. 2008 Aug;11(4):747-56.   READ A SUMMARY

  Public Library of Science
● Protective effect of human amniotic fluid stem cells in an immunodeficient mouse model of acute tubular necrosis.Perin L, Sedrakyan S, Giuliani S, Da Sacco S, Carraro G, Shiri L, Lemley KV, Rosol M, Wu S, Atala A, Warburton D, De Filippo RE.PLoS One. 2010 Feb 24;5(2):e9357.

Reproductive Bio Medicine Online
Stem cells derived from amniotic fluid: new potentials in regenerative medicine. Cananzi M, Atala A, De Coppi P. Reprod Biomed Online. 2009;18 Suppl 1:17-27. PMID: 19281660 [PubMed - indexed for MEDLINE]

Scandinavian Journal of Urology and Nephrology
Substantial detrusor overactivity in conscious spontaneously hypertensive rats with hyperactive behaviour. Jin LH, Andersson KE, Kwon YH, Park CS, Yoon SM, Lee T. Scand J Urol Nephrol. 2008 Nov 25:1-5.

Scientific World Journal
Tissue engineering of the penis. Patel MN, Atala A. ScientificWorldJournal. 2011;11:2567-78. Epub 2011 Dec 29. Review.

Stem Cells
Human amniotic fluid stem cells can integrate and differentiate into epithelial lung lineages. Carraro G, Perin L, Sedrakyan S, Giuliani S, Tiozzo C, Lee J, Turcatel G, De Langhe SP, Driscoll B, Bellusci S, Minoo P, Atala A, De Filippo RE, Warburton D. Stem Cells. 2008 Nov;26(11):2902-11. Epub 2008 Aug 21.

Stem Cells and Development
Non-invasive longitudinal tracking of human amniotic fluid stem cells in the mouse heart. Delo DM, Olson J, Baptista PM, D'Agostino RB Jr, Atala A, Zhu JM, Soker S. Stem Cells Dev. 2008 Dec;17(6):1185-94.

High transduction efficiency of human amniotic fluid stem cells mediated by adenovirus vectors. Grisafi D, Piccoli M, Pozzobon M, Ditadi A, Zaramella P, Chiandetti L, Zanon GF, Atala A, Zacchello F, Scarpa M, De Coppi P, Tomanin R. Stem Cells Dev. 2008 Oct;17(5):953-62.

Stem Cell Review
Sources of stem cells for regenerative medicine. Hipp J, Atala A. Stem Cell Rev. 2008 Spring;4(1):3-11. Review.

The Journal of Sexual Medicine
Effects of natriuretic peptides on intracavernous pressure and blood pressure in conscious rats. Aizawa N, Ishizuka O, Ogawa T, Mizusawa H, Igawa Y, Nishizawa O, Andersson KE. J Sex Med. 2008 Oct;5(10):2312-7

Regenerative medicine strategies for treatment of neurogenic bladder. Soler R, Fullhase C, Atala A. Therapy. 2009;6(2):177-184.

Tissue Engineering, Part A
● Co-administration of PDGF-BB and VEGF within bladder acellular matrix enhance smooth muscle regeneration and vascularization for bladder augmentation in a rabbit model. Zhou LH,  Yang B,  Sun C, Qiu XF, Sun ZY, Chen Y, Zhang Y (a co-corresponding author), and Dai YT.  Tissue Engineering Part A. 2012 (IF 4.4, Online)    

Functional Recovery of Completely Denervated Muscle: Implications for Tissue Engineered Muscle. Kang SB, Olson JL, Atala A, Yoo J. Tissue Eng Part A. 2012 May 4. [Epub ahead of print]

Further development of a tissue engineered muscle repair construct in vitro for enhanced functional recovery following implantation in vivo in a murine model of volumetric muscle loss injury.Corona BT, Machingal MA, Criswell T, Vadhavkar M, Dannahower AC, Bergman C, Zhao W, Christ GJ.Tissue Eng Part A. 2012 Jun;18(11-12):1213-28. Epub 2012 May 10.

Characterization of urine-derived stem cells obtained from upper urinary tract for use in cell-based urological tissue engineering. Bharadwaj S, Liu G, Shi Y, Markert C, Andersson KE, Atala A, Zhang Y. Tissue Eng Part A. 2011 Aug;17(15-16):2123-32.

A tissue-engineered muscle repair construct for functional restoration of an irrecoverable muscle injury in a murine model.Machingal MA, Corona BT, Walters TJ, Kesireddy V, Koval CN, Dannahower A, Zhao W, Yoo JJ, Christ GJ. Tissue Eng Part A. 2011 Sep;17(17-18):2291-303. Epub 2011 Jul 28.

Repair of peripheral nerve defects in rabbits using keratin hydrogel scaffolds. Hill PS, Apel PJ, Barnwell J, Smith T, Koman LA, Atala A, Van Dyke M. Tissue Eng Part A. 2011 Jun;17(11-12):1499-505. Epub 2011 Mar 23.

Differentiation of human bone marrow mesenchymal stem cells into bladder cells: potential for urological tissue engineering. Tian H, Bharadwaj S, Liu Y, Ma PX, Atala A, Zhang Y.Tissue Eng Part A. 2010 May;16(5):1769-79.

Endothelialization of heart valve matrix using a computer-assisted pulsatile bioreactor.
Lee DJ, Steen J, Jordan JE, Kincaid EH, Kon ND, Atala A, Berry J, Yoo JJ. Tissue Eng Part A. 2009 Apr;15(4):807-14. PMID: 19320610

Inkjet-mediated gene transfection into living cells combined with targeted delivery. Xu T, Rohozinski J, Zhao W, Moorefield EC, Atala A, Yoo JJ. Tissue Eng Part A. 2009 Jan;15(1):95-101.

A method to improve cellular content for corporal tissue engineering. Eberli D, Susaeta R, Yoo JJ, Atala A. Tissue Eng Part A. 2008 Oct;14(10):1581-9.

Bioreactor Maintained Living Skin Matrix. Ladd MR, Lee SJ, Atala A, Yoo JJ. Tissue Eng Part A. 2008 Sep 26. [Epub ahead of print]   READ A SUMMARY  

Cyclic mechanical preconditioning improves engineered muscle contraction. Moon du G, Christ G, Stitzel JD, Atala A, Yoo JJ. Tissue Eng Part A. 2008 Apr;14(4):473-82.   READ A SUMMARY  

Tissue Engineering, Part C: Methods
Efficient Recovery of Endothelial Progenitors for Clinical Translation. Tillman BW, Yazdani SK, Geary RL, Corriere MA, Atala A, Yoo JJ. Tissue Eng Part C Methods. 2009 Jan 6. [Epub ahead of print]   READ A SUMMARY  

Regenerative medicine and organ transplantation: past, present, and future. Orlando G, Wood KJ, Stratta RJ, Yoo JJ, Atala A, Soker S. Transplantation. 2011 Jun 27;91(12):1310-7.

Tissue engineering a complete vaginal replacement from a small biopsy of autologous tissue. De Filippo RE, Bishop CE, Filho LF, Yoo JJ, Atala A. Transplantation. 2008 Jul 27;86(2):208-14. Erratum in: Transplantation. 2008 Sep 15;86(5): 751.. De Philippo, Roger E [corrected to De Filippo, Roger E].

Transplant International
Regenerative medicine as applied to solid organ transplantation: current status and future challenges. Orlando G, Baptista P, Birchall M, De Coppi P, Farney A, Guimaraes-Souza NK, Opara E, Rogers J, Seliktar D, Shapira-Schweitzer K, Stratta RJ, Atala A, Wood KJ, Soker S.Transpl Int. 2011 Mar;24(3):223-32. doi: 10.1111/j.1432-2277.2010.01182.x. Epub 2010 Nov 10. Review.

Urologia Internationalis
● Photo-selective vaporization of the prostate with Green-Light HPS  120-W laser for benign prostatic hyperplasia: 36 months' follow-up. . Zang Y, Xue B, Zhang Y, Yang D, Gao J, Sun C, Cui Y and Shan Y. The Urologia Internationalis 2012 (IF 0.9, Online)

Urology Clinics of North America
Regenerative medicine and tissue engineering in urology. Atala A. Urol Clin North Am. 2009 May;36(2):199-209. PMID: 19406321

World Journal of Urology
Erythropoietin producing cells for potential cell therapy. Aboushwareb T, Egydio F, Straker L, Gyabaah K, Atala A, Yoo JJ. World J Urol. 2008 Aug;26(4):295-300.   READ A SUMMARY  

Tubularized urethral replacement with unseeded matrices: what is the maximum distance for normal tissue regeneration? Dorin RP, Pohl HG, De Filippo RE, Yoo JJ, Atala A. World J Urol. 2008 Aug;26(4):323-6. Epub 2008 Aug 6.

Tissue engineering in urology. Atala A, Yoo JJ. World J Urol. 2008 Aug;26(4):293-4. No abstract available.

Cavernous nerve regeneration using acellular nerve grafts. Connolly SS, Yoo JJ, Abouheba M, Soker S, McDougal WS, Atala A. World J Urol. 2008 Aug;26(4):333-9. Epub 2008 Jul 2.

A collagen matrix derived from bladder can be used to engineer smooth muscle tissue. Kim BS, Atala A, Yoo JJ. World J Urol. 2008 Aug;26(4):307-14. Epub 2008 Jul 2.

Tissue engineered testicular prostheses with prolonged testosterone release. Raya-Rivera AM, Baez C, Atala A, Yoo JJ. World J Urol. 2008 Aug;26(4):351-8. Epub 2008 Jun 7. 












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Institute for Regenerative Medicine

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Richard H. Dean Biomedical Building
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Cell and Tissue Types

Cell and Tissue Types

Scientists at the Wake Forest Institute for Regenerative are working to engineer replacement tissues and organs and develop healing cell therapies for more than 30 different areas of the body.

Last Updated: 07-14-2014
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