When tissues in the body are deprived of oxygen, the
irreversible process of tissue death begins. For military
personnel, this can occur when blast injuries damage blood vessels
and interrupt the blood supply to the arms or legs. But what if
there was a way to temporarily provide oxygen to muscle tissue and
keep it alive?
Institute scientists are using safe, natural chemicals that
generate oxygen in a variety of projects - from a treatment to
promote limb salvage to incorporating the particles into organ
scaffolds. With limb salvage, the particles, in the form of an
injectable gel, could potentially slow muscle death until a surgeon
could operate and restore the blood supply. The goal is to
develop a treatment that medics could carry with them - as a way to
buy time and provide a temporary burst of oxygen until a patient
could get medical treatment.