James J. Yoo, MD, PhD
James J. Yoo, M.D., Ph.D., Professor, Associate Director and Chief Scientific Officer
Dr. Yoo is a surgeon and researcher. He is currently a faculty member at the Wake Forest Institute for Regenerative Medicine and is cross-appointed to the Department of Urology, Physiology and Pharmacology, and Biomedical Engineering. Dr. Yoo received his Bachelor’s Degree in biology from the University of Illinois in 1984.
SYNOPSIS OF AREA OF INTEREST: Clinical translation of tissue engineering and cell-based therapies
DETAILED AREA OF INTEREST: Dr. Yoo's research efforts have been directed toward the clinical translation of tissue engineering technologies and cell-based therapies by developing new therapeutic modalities for the functional repair and replacement of diseased tissues and organs. A tissue engineering approach involves the use of bio-matrices alone, wherein the body's natural ability to regenerate is used to orient and direct new tissue growth, or the use of matrices with cells. Recent advancement of stem cell technologies has further expanded the applications of tissue engineering and cell-based therapies. Dr. Yoo's background in cell biology and medicine has facilitated the transfer of numerous cell-based technologies from the bench-top to the bedside. He has been involved in the engineering of applicable tissues and organs, including the blood vessels, heart valves, kidney, cartilage, bone, muscle, bladder and urethra for clinical translation. His extensive experience in cell culture, biomaterials design, surgical techniques and animal handling has contributed to achieving functional tissues and organs for successful pre-clinical and clinical studies.