Vervet Research Colony Request Form Instructions
The Wake Forest/UCLA Vervet Research Colony (VRC) is a large, multigenerational, pedigreed colony of vervet monkeys (African green monkeys, Chlorocebus aethiops). The colony is supported in part by a National Center for Research Resources (NCRR) P40 grant at the Wake Forest University Primate Center (WFUPC). One purpose of the P40 grant is to promote the use of the vervet as an animal model for biomedical research. Animals in the colony can be used for genetics-based studies of behavior or diseases, and would be especially valuable for researchers at institutions that do not have nonhuman primate housing available. Scientists interested in using this colony can utilize blood or tissue samples collected from the colony, or can purchase animals directly, for either on-site or off-site studies.
All research using VRC must be reviewed and approved by the colony’s scientific board and the Wake Forest Animal Care and Use Committee (ACUC) before any work can be initiated. The scientific board meets monthly to assess the scientific value of each request and to determine whether or not animals/samples/data can be made available. This includes all requests for:
- The purchase of animals for use outside the colony
- The use of animals within the colony for the collection of blood/tissue samples, behavioral observations or other kinds of testing
- The use of the VRC sample/tissue repository
- The use of the VRC data repository
All requests must be submitted using the VRC's Request Form. Please contact Dr. Jorgensen if you have any questions about how the form should be completed. Details on how to fill out the specific sections of the request form are included below:
Please include all relevant contact information.
Please include the date by which you would like the request completed.
Please indicate whether your proposed project would be supported by NIH funds (i.e., through a grant already funded or through a grant which will be submitted to NIH). Since the colony is partially supported by NCRR, NIH-funded requests will take priority.
Include a project name that clearly describes your project. Include a lay summary of the proposed project that will help the scientific board to assess the following items:
1. The relevance of the project
2. The scientific merit of the project
3. The details of the procedures proposed
4. The impact the work will have on the animals
5. Whether or not the study will take place within the colony or not
Numbers of Animals
Indicate the number, sex and age of the subjects requested. Indicate whether or not you would like to purchase these animals or whether the samples/procedures would take place within the colony. If you are only requesting data or samples already in the repository enter zero.
Indicate whether or not the proposed project would interfere with the simultaneous or future use of the same animals. If yes, include a description of how the animals will be impacted. Keep in mind that the colony is managed as a shared resource with multiple investigators often using the same animals simultaneously.
The services requested section is for all procedures/sample collections that will take place within the colony. If the requested animals are to be purchased and removed from the colony and no other data and/or samples are requested then this section can be skipped. Check the appropriate box next to any and all procedures that will be done within the colony. Include enough detail so that scientific board can determine the impact on the animals.
Specify the type of data that will be requested. This could include pedigree or genetic information, behavioral and/or physiological phenotypes. The board may suggest that some of these data be used to enhance the proposed project.
Please indicate if any phenotypic or genetic data will be added to the VRC data repository. Projects that add to the data repository will be given priority over those that do not.