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Conditions and Treatments

Diseases and Conditions 


Intravenous Drug Infusions

An intravenous infusion (IV) is a method of administering drugs and/or fluids through a needle inserted directly into a vein. Some of the rheumatoid conditions or diseases for which IV Drug Infusion is used are: Rheumatoid Arthritis, Lupus and Psoriatic arthritis.

IV Cytoxan (Intravenous)

Cytoxan is an immunosuppressive medication used in the treatment of lupus. Cytoxan, the brand name for cyclophosphamide, is one of several medications that are used in the treatment of lupus.  Depending upon the immunosuppressive drug used, it may be administered in pill form, weekly injections or by intravenous (IV) pulse therapy (injection given monthly).

Lupus (systemic lupus erythematosus, or SLE) is an autoimmune disease, in which the immune system attacks the body's own tissues as though they were foreign substances. Immunosuppressive medications, including cytoxan, reduce inflammation and suppress the immune system. In higher doses, these types of medications are also used to treat certain forms of cancer.

Cytoxan, and other immunosuppressive medications, are used to treat the severe kidney disease associated with lupus.  Cytoxan is more effective, yet more toxic than other immunosuppressive medications.  When given intravenously once a month for six months, it maintains kidney function in up to 80% of people with severe lupus. This benefit, together with fewer disease flares, can be maintained with less frequent treatments over one to two years.  It reduces inflammation of kidneys and other affected organs.

The most serious side effects of immunosuppressants are lowered white blood cell counts and increased risk of infection.  When immunity is lowered, the body is less able to defend against viral, bacterial and fungal infections such as a common herpes-type virus (cytomegalovirus [CMV]), shingles, staphylococcus, and yeast.  

Quick Reference

Rheumatology & Immunology

Clinic 336-716-4209
Fax 336-716-9821

8 am to 5pm, Mon - Fri

Clinic Locations:

  • Medical Plaza - Miller
  • Shepherd Street
  • 7th floor Janeway Clinical Sciences Tower
Physician referral required for this clinic.



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Last Updated: 09-30-2016
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