Cardiovascular Research Training Program

Training Program Faculty

The Clinical CV Research Training Faculty

The training program is directed by Dr. David M. David M. Herrington, MDHerrington, MD, MHS, Professor of Medicine/Cardiology and Vice-Chair for Research in the Department of Internal Medicine. Dr. Herrington received his own research training at the Johns Hopkins Hospital in the Welsh Center for Prevention, Epidemiology and Clinical Research and at the Johns Hopkins School of Hygiene and Public Health under the Direction of Dr. Paul Whelton, as well as during a Preventive Cardiology fellowship at The Johns Hopkins Hospital under the direction of Dr. Tom Pearson. Since his arrival at Wake Forest in 1990, Dr. Herrington has established an extensive track record of training and mentoring. Specifically with respect to training grants, in addition to serving as the director for this program, Dr. Herrington serves on six other training grants at Wake Forest. Dr. Herrington has served as an individual mentor or research advisor for over 50 trainees and junior faculty members at Wake Forest and other institutions across the country including Harvard University, U. of California at San Francisco, the University of Washington, and Virginia Tech.  

Dr. Herrington also has an extensive track record of research and publication.  He has been continuously funded by the AHA or the NIH since his first year on the faculty at Wake Forest and has been the PI for more than $45M in extramurally funded research. He has been actively involved in clinical trials and cardiovascular and genetic epidemiology with a focus on heart disease in women, endothelial function and the pathogenesis and prevention of atherosclerosis. He has led several NIH-funded initiatives related to genomics of cardiovascular disease and currently leads a U01 for a large multi-center study of the associations between genetic variants, proteomic patterns and premature atherosclerosis. He has also had R01 funding to study the development and validation of new computational approaches to identify complex interactions among genetic and environmental factors which could provide novel insights into the pathophysiology of disease. In addition to his role as PI, he has been a co-investigator or served on various operational, scientific, data and safety monitoring or advisory committees for many other observational studies and clinical trials including most recently the Multi-Ethnic Study of Atherosclerosis (MESA) and related ancillary studies, the Jackson Heart Study (JHS), and the Pharmacogenetic Network for Cardiovascular Risk Therapy (PARC), and the Preventing Anthracycline Cardiovascular Toxicity with Statins Trial (PACTS). Dr. Herrington has over 300 publications and currently serves as an Associate Editor for Circulation Cardiovascular Genetics. In 2007, Dr. Herrington received the prestigious WFUHS Established Clinical Investigator Award, and in 2014 he was appointed the Dalton McMichael Endowed Professor in Cardiology. 

Dr. Elsayed Soliman joins Dr. Herrington as Associate Director.  Dr. Soliman MD, MSc , MS, Associate Professor of Epidemiology and Internal Medicine-Cardiology, is a cardiovascular epidemiologist with formal training in cardiology, epidemiology and health services research. Currently, Dr. Soliman serves as Director of the Epidemiological Cardiology Research Center (EPICARE) at Wake Forest School of Medicine.  He is also Principal Investigator for the Electrocardiogram (ECG) Reading Center of several population studies and clinical trials including Systolic Blood Pressure Intervention Trial (SPRINT), Action to Control Cardiovascular Risk in Diabetes Follow-On (ACCORDION), Prospective Cohort Study of Chronic Renal Insufficiency (CRIC), Epidemiology of Diabetes Intervention & Complications Study (EDIC), International Network for Strategic Initiatives in Global HIV Trials (INSIGHT), The Multi-Ethnic Study of Atherosclerosis (MESA), Action for Health in Diabetes (LookAHEAD), The Atherosclerosis Risk in Communities Study (ARIC), REasons for Geographic and Racial Differences in Stroke (REGARDS) and many others. 

The Clinical CV Research Training program relies on a multi-disciplinary collaboration of faculty members from the Departments of Medicine/Cardiology, Public Health Sciences, Surgical Sciences, Physiology and Pharmacology and Biochemistry. Dr. Herrington is joined by the following program faculty:

  • Greg Burke, MD, MSc, Professor and Chair, Public Health Sciences - chronic disease research in populations, especially cardiovascular disease
  • Donald W. Bowden, MD, Professor of Biochemistry and Internal Medicine/ Endocrinology & Metabolism, Associate Director, Center for Human Genomics - a wide range of human genetic studies of both single gene disorders, cystic fibrosis, multiple endocrine neoplasia, retinitis pigmentosa, and maturity onset diabetes of the young, and complex diseases, Type 1 and Type 2 diabetes, autoimmune thyroid disease, recurrent otitis media, end stage renal disease, diabetic nephropathy, and diabetic cardiovascular disease
  • Dalane Kitzman, MD, Associate Professor, Medicine/ Cardiology and Director of Echocardiography - aging of the heart, exercise physiology, diastolic dysfunction, heart failure, and echocardiography
  • Lynne E. Wagenknecht, DrPH, Professor and Section Head, Section on Epidemiology, Department of Public Health Sciences - a chronic disease epidemiologist with an extensive research portfolio in the areas of cardiovascular disease and diabetes
  • K. Bridget Brosnihan, PhD, Professor of Surgical Sciences, Hypertension and Vascular Research Center and Physiology & Pharmacology - assays of angiotensin system hormones and enzymes, measurements of inflammatory markers, cytokines, and growth factors
  • W. Gregory Hundley, MD, Professor of Internal Medicine/ Cardiology and Radiologic Sciences – cardiac MRI and cardiovascular cohort studies and clinical trials
  • Timothy Howard, PhD, Associate Professor of Pediatrics/ Center for Human Genomics – genetic studies of pulmonary, cardiovascular, and cerebrovascular disease
  • Dr. Alain Bertoni, MD, PhD, Professor, Department of Epidemiology & Prevention/ Chair PHS - diabetes and its complications, cardiovascular disease, quality improvement in chronic disease, and ethnic disparities in health and healthcare
  • Chadwick Miller, MD, MS, Associate Professor, Executive Vice-Chair, and Director of Clinical Research in the Department of Emergency Medicine – investigations of managing chest pain patients with stress  cardiac magnetic resonance (CMR) imaging 3
  • Joseph Yeboah, MD, MS, Assistant Professor, Department of Internal Medicine/ Cardiology - studies of cardiovascular risk, residual cardiovascular risk, methods of quantifying residual risk using imaging such as echocardiography, magnetic resonance imaging, computed tomography, nuclear medicine and interventional modalities aimed at reducing residual cardiovascular risk.
  • Carlos Jose Rodriguez MD, MPH,Associate Professor, Epidemiology and Prevention, and Cardiology – studies  characterizing cardiac structure and function within the Hispanic Community Health Study / Study of Latinos (HCHS/SOL) cohort.
  • John Parks, PhD, Professor and Chief of Molecular Medicine, Department of Internal Medicine -  investigations of atherosclerosis and lipoprotein metabolism studies in non-human primate and mouse models of atherosclerosis. 

     

     

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