Guorui Deng - Doctoral Candidate

Gary Deng

Guorui Deng, BS
PhD Student (Department of Cancer Biology)

Education:  BS – Biochemistry/Cell Biology, Bucknell University, Lewisburg, PA
Laboratory Department: Department of Cancer Biology, Hypertension and Vascular Research Center

Advisors: Dr. Ann Tallant and Dr. Patricia E. Gallagher

Current Research: My research focuses on determining the molecular mechanisms for the inhibition of triple negative breast cancer growth and progression by the heptapeptide hormone Angiotensin-(1-7), [Ang-(1-7)]. I am interested in identifying mechanisms of how the heptapeptide hormone exerts its anti-cancer effects on the oncogenic  c-Met receptor tyrosine kinase and its downstream signaling to inhibit disease progression and subsequent metastasis. Successful completion of my studies will provide support for Ang-(1-7) to serve as a novel targeted therapeutic for these patients. 

 Poster Presentations:

Guorui Deng, Patricia E. Gallagher, E. Ann Tallant. “Angiotensin-(1-7) Attenuates Triple Negative Breast Cancer Progression By Targeting C-Met Signaling and Downstream ERK1/2 Signaling,” (2014), RAS Oncogenes: From Biology to Therapy, Lake Buena Vista, FL, Poster Presentation.

Guorui Deng, Patricia E. Gallagher, E. Ann Tallant. “Angiotensin-(1-7) Attenuates Triple Negative Breast Cancer Progression By Targeting C-Met Signaling,” (2013), Wake Forest University Department of Surgical Sciences Research Day, Poster Presentation.

Honors and Awards:

Recipient of Department of Cancer Biology Training Grant, 08/2013

Bucknell University Full Tuition Scholarship Award, 2006-2010

 

Quick Reference

Hypertension & Vascular Research Center
Debra I. Diz, PhD
Program Director

ddiz@wakehealth.edu

Samantha Statham

Phone: 336-716-0757
FAX: 336-716-2456

PREP@wakehealth.edu

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