Functional Genomics and Physiology Faculty
Studies in this area explore the contribution of specific genes to both physiologic and pathophysiologic processes. A major focus is on the experimental manipulation of genes and gene expression in animal models and cell-based systems and analyses of phenotypic consequences.
Peter Antinozzi Functional mapping of disease-susceptibility loci with emphasis on diabetes; cell-based functional assessment of disease-associated allelic variants; metabolism-secretion coupling in pancreatic beta-cells. Faculty Profile & Publications / Lab Page
Paul Dawson Regulation and genetics of hepatic and intestinal cholesterol and bile acid metabolism. Faculty Profile & Publications
Ashok Hegde Molecular biological, electrophysiological, and behavioral approaches to study questions on long-term memory. Faculty Profile & Publications
Doug Lyles Virus assembly; molecular pathogenesis of virus infection. Faculty Profile & Publications / Lab Page
Charles McCall Neutrophil biology and biochemistry; inflammation of lung; signal transduction; phospholipid metabolism; expression of IL-1, TNFa and cyclooxygenase genes in phagocytes. Faculty Profile & Publications
Lance Miller Transcriptional and genomic alterations of the "oncogenome" that drive tumorigenesis and predict patient outcomes. Faculty Profile & Publications / Lab Page
Carol Milligan Neuronal development, degeneration, and plasticity after injury: identification and characterization of differentially expressed genes in motoneuron cell death. Faculty Profile & Publications
Nila Mishra New therapeutic targets for the treatment and prevention of SLE. Faculty Profile & Publications / Research Interests
Barbara Nicklas Research focuses on understanding the metabolic and hormonal adaptations to exercise and dietary interventions in older individuals, and the role of genetics in determining these adaptations. Faculty Profile & Publications
Ron Oppenheim Developmental neurobiology; programmed cell death; growth factors and neurotrophic molecules. Faculty Profile & Publications
David Ornelles Molecular virology of adenovirus; the oncolytic and oncogenic potential of human adenovirus. Faculty Profile & Publications / Lab Page
John Parks Structure-function relationships of lecithin:cholesterol acyltransferase and high-density lipoproteins. Faculty Profile & Publications / Current Research
Tom Register Modulation of the expression of cytokines and connective tissue genes during early atherogenesis. Faculty Profile & Publications
Greg Shelness Intracellular protein targeting and transport; lipoprotein assembly and secretion. Faculty Profile & Publications / Research Interests
Mary Sorci-Thomas Regulation of apolipoprotein gene expression; structure-function relationships of apoprotein A-I. Faculty Profile & Publications / Current Research
Ann Tallant Signal transduction; regulation of growth; hypertension; cancer treatment/prevention. Faculty Profile & Publications / Molecular and Cell Biology Core Lab / Hypertension Cell and Molecular Biology Laboratory
Richard Weinberg Structure and function of human apolipoprotein A-IV (apo A-IV), an intestinal protein synthesized during lipid absorption and incorporated into the surface of nascent chylomicrons. Faculty Profile & Publications