John Cravero, PhD
Office of Science Patent Attorney
U.S. Department of Energy
J.D., Chicago-Kent College of Law, 2012
Ph.D., Molecular Medicine and Translational Science Graduate
Program, May 2008
Wake Forest University Graduate School of Arts and Sciences
B.A., Augustana College, Rock Island, IL, 2005
Osteoarthritis, IGF-1 signaling pathways in the chondrocyte, the decrease in the chondrocyte’s response to IGF-1 that occurs with age and OA, and the role of age-related oxidative stress and how it contributes to the decreased IGF-1 response of the chondrocyte.
Postdoctoral Northwest University, August 2009
Cravero JD, Carlson CS, Im HJ, Yammani RR, Long D, Loeser RF. Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis. Arthritis Rheum. 2009 Feb;60(2):492-500.
Starkman, B.G., Cravero, J.D., DelCarlo, M. Jr., Loeser, R.F. IGF-1 stimulation of proteoglycan synthesis by chondrocytes requires activation of the PI3-kinase pathway but not ERK MAPK. Biochem. J. (2005) 389: 723-729.
For a listing of additional publications, refer to PubMed, a service provided by the National Library of Medicine.