Anna Misior, PhD
Lineberger Comprehensive Cancer Center
Ph.D., Molecular Medicine, 2008
Wake Forest University
School of Medicine
BS, Biology/Chemistry, 2001
Mars Hill College, Mars Hill, NC
Certified Clinical Research Coordinator, 2002-2006; ACRP
Intracellular signaling events which regulate growth of human airway smooth muscle cells in response to inflammation and relevant pharmacological agents (primarily corticosteroids and COX-2 inhibitors). Working in Dr. Earp’s lab on Her4 signaling in breast cancer cells.
Yan H, Deshpande DA, Misior AM, Miles MC, Saxena H, Riemer EC, Pascual RM, Panettieri RA, Penn RB. Anti-mitogenic effects of β-agonists and PGE2 on airway smooth muscle are PKA dependent. FASEB J. 2011 Jan;25(1):389-97. Epub 2010 Aug 30. PMID: 20805374
Misior A, Deshpande D, Loza M, Hipp J, Penn R. PKA- and glucocorticoid- dependent regulation of gene expression in human airway smooth muscle cells. Am J Respir Cell Mol Biology. 2009 Jul;41(1):24-39. PMID: 19059887
Kong K, Gandhi U, Martin T, Anz C, Misior A, Pascual R, Deshpande D, Penn R. Endogenous Gs-coupled receptors in smooth muscle exhibit differential susceptibility to GRK-mediated desensitization. Biochemistry. 2008 Sep 2;47(35):9279-88. PMID: 18690720
Misior A, Yan H, Pascual R, Deshpande D, Panettieri R, Penn R. Mitogenic effects of cytokines on smooth muscle are critically dependent on protein kinase A and are unmasked by steroids and cyclooxygenase inhibitors. Mol Pharmacol. Feb 2008; 73 (2): 566-574. PMID: 17993511
Huang Y, Misior A, Li L. Novel role and regulation of the interleukin-1 receptor associated kinase (IRAK) family proteins. Cell Mol Immun. 2005; 2 (No 1): 36-39. PMID: 16212909
For a listing of additional publications, refer to PubMed, a service provided by the National Library of Medicine.