Revati Wani, PhD
Oncology Drug Discovery and Bioprocess Development
San Diego, CA
PhD Molecular Medicine and Translational Science 2007-2012
Wake Forest School of Medicine
MS (Biochemistry), 2006, University of Pune, India
BS (Chemistry) 2004, Ferguson College, India
Advisor: Cristina M. Furdui, Ph.D.: Internal Medicine (Molecular Medicine)
My current research involves investigation of the role of post-translational modifications such as oxidation and phosphorylation on regulating growth factor mediated intracellular signaling following a proteomics approach utilizing high throughput techniques such as mass spectrometry. More specifically, the interest is in investigating the effect of oxidation on phosphorylation of signaling kinases and its impact on downstream molecular signaling. Understanding these oxidative modifications is of critical significance in explaining the signaling perturbations underlying ‘oxidative pathogenesis’ of several clinical conditions such as atherosclerosis and cancer.
Honors and Awards:
2011: Lucy Robbins Fellowship Award: For conducting cancer-related research
2006: Junior Research Fellowship Award: Indian Council of Medical Research
2005: Participated in the International Conference on ‘Fifty Years of Discovery of Triple Helical Structure of Collagen: Progress & Perspectives’
2005: Qualified the Indian Institute of Technology (IIT) Examination
1999: Received the Rotary Youth
Wani R, Qian J, Yin L, Bechtold E, King SB, Poole LB, Paek E, Tsang AW, Furdui, CM. Isoform-specific regulation of Akt by PDGF-induced reactive oxygen species. Proc Natl Acad Sci USA 2011 Jun 28;108(26);10550-5.
Wani R, Kodam KM, Gawai KR, Dhakephalkar PK. Chromate reduction by Burkholderia cepacia MCMB-821 isolated from the pristine habitat of alkaline crater lake. Applied Microbiology Biotechnology (2007) 75:627-632
For a listing of additional publications, refer to PubMed, a service provided by the National Library of Medicine.