Skip Navigation

Ryne DeBo, PhD

rdebo

Postdoctoral Fellow
Lab of Thomas Register, PhD, Pathology (Comparative Medicine)
Wake Forest School of Medicine

Year Matriculated:  
2011

E-mail:   rdebo@wakehealth.edu

Education: Ph.D., Molecular Medicine and Translational Science Graduate Program, May 2017
Wake Forest University Graduate School of Arts and Sciences

Lake Forest College, BA
Rush University, MS

Advisor:  Dr. Thomas Register

 Research Interest:  
Obesity, Cardiovascular Disease, and Atherosclerosis

Honors:

Research featured on cover of July 2016 journal, Radiation Research.
About the Cover: DeBo et al., “Late Effects of Total-Body Gamma Irradiation on Cardiac Structure and Function in Male Rhesus Macaques”. Winner of the 2017 Radiation Research Editors' Award. He will be recognized at the 2017 RRS Annual Meeting in Cancun.

Meeting Abstracts (Presenter)

Late effects of gamma irradiation on cardiovascular structure and function and circulating biomarkers in male rhesus macaques
Ryne J. DeBo, BA, MS; Cynthia J. Lees, DVM, PhD; Greg Dugan, DVM; J Mark. Cline, DVM, PhD; and Thomas C. Register, PhD, Wake Forest School of Medicine, Winston-Salem, NC
Presentation at the 61st Annual Meeting of the Radiation Research Society, Weston, FL, September 19th-22nd, 2015.

Late effects of radiation exposure on cardiovascular structure and function and circulating biomarkers in adult rhesus macaques. 
Ryne J. DeBo, BA, MS; Greg Dugan, DVM; Cynthia J. Lees, DVM, PhD; J Mark. Cline, DVM, PhD; and Thomas C. Register, PhD, Wake Forest School of Medicine, Winston-Salem, NC
Comparative Medicine Research Day, Wake Forest University School of Medicine, July 16th, 2015.

Long Term Morbidity in Irradiated Nonhuman Primates
Cline JM, Dugan G, Lees C, Kavanagh K, Bourland JD, Hanbury D, Pfeiffer AM, Andrews R, DeBo R, Register TC, Caudell D, Chao NJ.
15th Annual International Congress of Radiation Research, Kyoto, Japan, May 25th-29th, 2015.

Ryne J. DeBo, BA, MS; Greg Dugan, DVM; Cynthia J. Lees, DVM,PhD; J Mark. Cline, DVM, PhD; and Thomas C. Register, PhD, Wake Forest School of Medicine, Winston-Salem, NC. Late effects of radiation exposure on cardiovascular structure and function and circulating biomarkers in adult rhesus macaques. 
 
Poster presented at the 59th Annual Meeting of the Radiation Research Society, New Orleans, LA, September 18th, 2013.

Poster finalist at the 12th Annual Charlotte Life Sciences Conference, Charlotte, NC, October 24th, 2013. 

Poster presented at the Radiation Oncology & Imaging Program Annual Retreat, Duke University, Durham, NC, March 10th, 2014.

Oral Presentations:

Molecular, Cellular and Cardiovascular effects of Total Body Irradiation in Non-Human Primate Models. Ryne J. DeBo, BA, MS. Comparative Medicine Research Day, Wake Forest University School of Medicine, July 16th, 2015.

Serum IL-10 and IL-15 Levels are Increased with Prior Exposure to Gamma Irradiation and are Associated with Radiation Sensitive Cardiac Phenotypes. Thomas C. Register; Ryne J. DeBo; Kris Michalson, DVM; Cynthia J. Lees, DVM, PhD; Greg Dugan, DVM; Greg Sempowski, PhD; Kylie Kavanagh, DVM; David Caudell, DVM, PhD; and J. Mark Cline, DVM, PhD, Wake Forest School of Medicine, Winston-Salem, NC and Duke University, Durham, NC 
Accepted for presentation at 62nd Annual Meeting of the Radiation Research Society, Waikoloa Village-Big Island, HI, October 16th-19th, 2016.

Publications:

DeBo RJ, Michalson KT, Lees CJ, Dugan GO, Hanbury DB, Caudell DL, Andrews RN, Vujaskovic Z, Batinic-Haberle I, Bourland JD, Cline JM, Register TC.  SOD mimetic (MnTnHex-2-PyP5+) alters cardiovascular gene expression profiles in the absence of phenotypic improvement in NHP’s following 10Gy irradiation to the thorax. In preparation, 2016.

DeBo RJ, Lees CJ, Dugan GO, Caudell DL, Michalson KT, Hanbury DB, Kavanagh K, Cline JM, Register TC. Late Effects of Total Body Gamma Irradiation on Cardiac Structure and Function in Male Rhesus Macaques. Radiation Research. 2016; 186. PubMed PMID: 27333082.

DeBo RJ, Register TC, Caudell DL, Sempowski GD, Dugan G, Gray S, Owzar K, Jiang C, Bourland JD, Chao NJ, Cline JM. Molecular and cellular profiling of acute responses to total body radiation exposure in ovariectomized female cynomolgus macaques. Int J Radiat Biol. 2015 Jun;91(6):510-8. PubMed PMID: 25786585

Kavanagh K, Dendinger MD, Davis AT, Register TC, DeBo R, Dugan G, Cline JM. Type 2 Diabetes is a Delayed Late Effect of Whole-Body Irradiation in Nonhuman Primates. Radiat Res. 2015 Apr;183(4):398-406. PubMed PMID: 25811716; PubMed Central PMCID: PMC4438751

Extracurricular:

Juvenile Diabetes Research Foundation (JDRF)
Registered Fundraiser and Participant, Amelia Island Ride to Cure Diabetes, Amelia Island, FL, October, 2016



 

 

 

Quick Reference

Contact Information
Molecular Medicine and Translational Science Graduate Program

Office 336-713-4259

Kay Collare

336-713-4259

kcollare@wakehealth.edu

Find A Doctor Ways to Give
Last Updated: 05-23-2017
Six Wake Forest Baptist Specialties Earn U.S. News RankingsComprehensive Cancer Centers National Designation is RenewedMagnet Hospital Recognition2015 Best DoctorsJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.

© Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157. All Rights Reserved.