Profile

Heidi Diana Klepin, M.D.

Heidi Diana Klepin, M.D.

Associate Professor, Hematology & Oncology
Sticht Center on Aging
Comprehensive Cancer Center

Clinical Specialties

Geriatric Oncology

Contact Information

New Patient Appointments: 336-716-WAKE
Returning Patient Appointments: 336-713-5440
Department: 336-716-4464

Email: hklepin@wakehealth.edu

Education & Training

  • M.D., Med Univ Of So Carolina-Charleston, 1998
  • B.S., University of North Carolina-Chapel Hill, 1994
  • M.S., WFU School of Medicine, 2008
  • Residency, Internal Medicine, North Carolina Baptist Hospital, 2001
  • Internship, Internal Medicine, North Carolina Baptist Hospital, 1999
  • Fellowship, Geriatric Medicine, WFU School of Medicine, 2002
  • Fellowship, Hematology And Oncology, WFU School of Medicine, 2006

Board Certifications

  • American Board of Internal Medicine, Internal Medicine
  • American Board of Internal Medicine, Internal Medicine, Geriatric Medicine
  • American Board of Internal Medicine, Internal Medicine, Hematology
  • American Board of Internal Medicine, Internal Medicine, Medical Oncology

Memberships

  • Am Geriatrics Society
  • Am Soc Of Clinical Oncology
  • Am Soc Of Hematology
Heidi Diana Klepin, M.D.

Heidi Diana Klepin, M.D.

Associate Professor, Hematology & Oncology Sticht Center on Aging
Comprehensive Cancer Center

Contact Information

Academic: 336-716-7975 | Department: 336-716-4464

Email: hklepin@wakehealth.edu

Recent Publications

Klepin HD, Mohile SG, Mihalko S. Exercise for older cancer patients: feasible and helpful? In: Extermann M, Fulop T, eds. Cancer and aging: from bench to clinics. Basel (Switzerland): Karger;2013: 146-157.

Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Pardee TS, Ellis LR, Powell BL. Geriatric assessment predicts survival for older adults receiving induction chemotherapy for acute myelogenous leukemia. Blood. 2013;121(21):4287-4294.

Hurria A, Togawa K, Owusu C, Klepin H, Gross C, Lichtman S, Gajra A, Bhatia S, Katheria V, Klapper S, Hansen K, Ramani R, Lachs M, Wong FL, Tew W. Predicting chemotherapy toxicity in older adults and the importance of geriatric assessment [reply to letter]. J Clin Oncol. 2012;30(5):561-562.

Foley KL, Song EY, Klepin H, Geiger A, Tooze J. Screening colonoscopy among colorectal cancer survivors insured by Medicaid. Am J Clin Oncol. 2012;35(3):205-211.

Alibhai SM, O'Neill S, Fisher-Schlombs K, Breunis H, Brandwein JM, Timilshina N, Tomlinson GA, Klepin HD, Culos-Reed SN. A clinical trial of supervised exercise for adult inpatients with acute myeloid leukemia (AML) undergoing induction chemotherapy. Leuk Res. 2012;36(10):1255-1261.

Maggiore RJ, Gross CP, Togawa K, Tew WP, Mohile SG, Owusu C, Klepin HD, Lichtman SM, Gajra A, Ramani R, Katheria V, Klapper SM, Hansen K, Hurria A. Use of complementary medications among older adults with cancer. Cancer. 2012;118(19):4815-4823.

Klepin HD, Powell BL. Management of myelodysplastic syndromes and acute leukaemia In: Sinclair AJ, Morley JE, Vellas B, eds. Pathy's principles and practice of geriatric medicine, vol 1. 5th ed. Oxford (UK): Wiley-Blackwell;2012: 375-385.

Mohile SG, Klepin HD, Rao AV. Considerations and controversies in the management of older patients with advanced cancer In: Govindan R, ed. American Society of Clinical Oncology 2012 educational book. Alexandria (VA): American Society of Clinical Oncology;2012: 321-328.

Foley KL, Tooze JA, Klepin HD, Song E-Y, Geiger AM. Adjuvant chemotherapy among medicaid-enrolled patients diagnosed with nonmetastatic colon cancer. Am J Clin Oncol. 2011;34(2):120-124.

Klepin HD, Danhauer SC, Tooze JA, Stott K, Daley K, Vishnevsky T, Powell BL, Mihalko SL. Exercise for older adult inpatients with acute myelogenous leukemia: a pilot study. J Geriatr Oncol. 2011;2(1):11-17.

Gajra A, Hardt M, Tew WP, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Ramani R, Brown J, et al. Primary dose reduction (PDR) of chemotherapy (chemo) in patients (Pts) older than age 65 with advanced cancer (Ca) and toxicity outcomes [abstract]. J Clin Oncol. 2011;29(Suppl):abstr 9037.

Klepin HD, Gajra A, Hardt M, Tew WP, Mohile SG, Owusu C, Gross CP, Lichtman SM, Ramani R, Katheria V, et al. Predictors of primary dose reduction (PDR) among patients (pts) age 65 and older receiving adjuvant chemotherapy (chemo) [abstract]. J Clin Oncol. 2011;29(Suppl):abstr 9003.

Owusu C, Klepin HD, Kimmick GG, Sutton L, Brufsky A. Safety and efficacy of single-agent adjuvant trastzumab in older women with breast cancer [abstract]. J Clin Oncol. 2011;29(15 Suppl):TPS109.

Geller R, Tooze JA, Powell BL, Klepin H. The prevalence and prognostic significance of polypharmacy in older adults treated for acute myelogenous leukemia (AML) [abstract]. J Am Geriatr Soc. 2011;59(Suppl 1):S57.

Horton JK, Gleason JF Jr, Klepin HD, Isom S, Fried DB, Geiger AM. Age-related disparities in the use of radiotherapy for treatment of localized soft tissue sarcoma. Cancer. 2011;117(17):4033-4040.

Hurria A, Togawa K, Mohile SG, Owusu C, Klepin HD, Gross CP, Lichtman SM, Gajra A, Bhatia S, Katheria V, et al. Predicting chemotherapy toxicity in older adults with cancer: a prospective multicenter study. J Clin Oncol. 2011;29(25):3457-3465.

Klepin HD, Geiger AM, Tooze JA, Kritchevsky SB, Williamson JD, Ellis LR, Levitan D, Pardee TS, Isom S, Powell BL. The feasibility of inpatient geriatric assessment for older adults receiving induction chemotherapy for acute myelogenous leukemia. J Am Geriatr Soc. 2011;59(10):1837-1846.

Klepin HD, Geiger AM, Tooze JA, Newman AB, Colbert LH, Bauer DC, Satterfield S, Pavon J, Kritchevsky SB. Physical performance and subsequent disability and survival in older adults with malignancy: results from the Health, Aging and Body Composition Study. J Am Geriatr Soc. 2010;58(1):76-82.

Klepin HD, Geiger AM, Costantino JP, Sink KM, Lawrence JA, Espeland MA. Association between domain-specific cognitive function and adherence to oral anti-cancer therapy: results from Cognition in the Study of Tamoxifen and Raloxifene (Co-STAR) [abstract]. J Am Geriatr Soc. 2010;58(Suppl 1):86-87.

Hurria A, Mohile S, Lichtman C, Owusu H, Klepin H, Gross C, Hansen K, Klapper S, Togawa K, Tew W. Geriatric assessment of older adults with cancer: baseline data from a 500 patient multicenter study [abstract]. J Clin Oncol. 2010;27(15 Suppl):9546.

Klepin HD, Tooze JA, Geiger AM, Kritchevsky S, Williamson J, Ellis LR, Levitan D, Pardee T, Isom S, Powell BL. Geriatric assessment predicts overall survival among older adults receiving induction chemotherapy for acute myelogenous leukemia [abstract]. Blood. 2010;116(21):653-654.

Klepin HD, Powell BL. Management of myelodysplasia in older adults In: Hurria A, Cohen HJ, eds. Practical geriatric oncology. New York: Cambridge University Press;2010: 221-229.

Hartmann EL, Kitzman D, Rocco M, Leng X, Klepin H, Gordon M, Rejeski J, Berry M, Kritchevsky S. Physical function in older candidates for renal transplantation: an impaired population. Clin J Am Soc Nephrol. 2009;4(3):588-594.

Klepin H, Mohile S, Hurria A. Geriatric assessment in older patients with breast cancer. J Natl Compr Canc Netw. 2009;7(2):226-236.

Klepin HD, Balducci L. Acute myelogenous leukemia in older adults. Oncologist. 2009;14(3):222-232.

Klepin HD, Powell BL. White cell disorders In: Halter JB, Ouslander JG, Tinetti ME, Studenski S, High KP, Asthana S, Hazzard WR, Wollard NF, eds. Hazzard's geriatric medicine and gerontology. 6th ed. New York: McGraw Hill Medical;2009: 1215-1227.

Klepin HD, Song EY, Geiger AM, Tooze JA, Foley KL. Influence of age on receipt of chemotherapy for adult Medicaid beneficiaries with metastatic colorectal cancer [abstract]. J Clin Oncol. 2009;27(15 Suppl):Abstr 9548.

Klepin HD, Ellis LR, Levitan D, Powell BL. Feasibility of inpatient geriatric assessment for older adults with acute myelogenous leukemia [abstract]. J Am Geriatr Soc. 2009;57(Suppl 1):S155.

Klepin H, Danhauer SC, Tooze J, Stott K, Jesse MT, Mihalko SL. Feasibility of a physical activity intervention for older adult inpatients with acute leukemia [abstract]. Gerontologist. 2009;49(Suppl 2):277.

Klepin HD, Danhauer SC, Tooze J, Mihalko SL. A pilot study of a physical activity intervention for older adult inpatients with acute myelogenous leukemia [abstract]. Crit Rev Oncol Hematol. 2009;72(Suppl 1):S16.

Mihalko SL, Danhauer SC, Tooze J, Cook LN, Daley K, Vishnevsky T, Klepin H. Quality of life and function in older adults with acute leukemia: a physical activity pilot intervention [abstract]. Gerontologist. 2009;49(Suppl 2):276.


Klepin HD, Geiger AM, Williamson J, Kritchevsky S, Tooze JA, Ellis LR, Levitan D, Isom S, Powell BL. Inpatient geriatric assessment detects impairment among older adults receiving induction chemotherapy for acute myelogenous leukemia [abstract]. Blood. 2009;114(22):570-571.

Foley KL, Tooze JA, Song EY, Klepin HD, Geiger AM. Receipt of chemotherapy among Medicaid-enrolled patients diagnosed with regional colon cancer [abstract]. J Clin Oncol. 2009;27(15 Suppl):e15016.

Klepin HD, Geiger AM, Tooze J, Newman AB, Colbert LH, Bauer DC, Satterfield S, Pavon J, Kritchevsky SB. Physical performance measures predict survival in older cancer patients: the Health Aging and Body Composition study (Health ABC) [abstract]. J Am Geriatr Soc. 2008;56(4):S169-S170.

Hurria A, Balducci L, Naeim A, Gross C, Mohile S, Klepin H, Tew W, Downey L, Gajra A, Owusu C, et al. Mentoring junior faculty in geriatric oncology: report from the Cancer and Aging Research Group. J Clin Oncol. 2008;26(19):3125-3127.

Klepin HD, Geiger AM, Tooze J, Newman AM, Colbert LH, Bauer DC, Satterfield S, Pavon JM, Kritchevsky S. Use of physical performance measures to predict future disability and mortality in older cancer patients: the Health Aging and Body Composition Study (Health ABC) [abstract]. J Clin Oncol. 2008;26(15 Suppl):Abstr 9553.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Hematology & Oncology

Clinical Specialties

Geriatric Oncology