Molecular Medicine Faculty Research Interests

Section of Molecular Medicine Researchers Cristina Furdui and Revati Wani at Mass Spectrometer

       Molecular Medicine Faculty

Brown, Candice M, PhD - Regulation of the brain's innate immune response by endogenous estrogens during acute and chronic inflammation

Furdui, Cristina, PhD - Dynamic analysis of signaling events (protein phosphorylation and oxidation) at    molecular and cellular level using quantitative, mass spectrometry based proteomics experiments; rapid enzyme kinetics.

 Liu, Tie Fu, PhD  - Understanding molecular mechanism(s) involved in gene silencing and immunosuppression during severe systemic inflammation (SSI), generation of new therapeutic interventions or preventions to improve poor SSI outcomes.  Experimental studies are focused on the epigenetic regulation and gene remodeling of proinflammatory cytokines during the initiation, adaptation and, especially, resolution of SSI; and on the interplay between the energy change and members of sirtuin family and NFk-B family in a THP-1 cell model and an animal model.

Loeser, Richard, MD - Lab: The cellular and molecular mechanisms that regulate cartilage destruction in osteoarthritis and the role of aging. Clinical: The genetics of osteoarthritis; exercise and weight loss interventions for osteoarthritis

McCall, Charles E., MD - The molecular events that control the inflammatory components of innate immunity

Parks, John S., PhD - Atherosclerosis/thrombosis, diabetes, hormones/cytokines/signaling, metabolism, nutrition

Rudel, Lawrence, PhD - Atherosclerosis/thrombosis, drugs/therapeutic agents pharm, metabolism, nutrition, transgenics 

Seeds, Michael C., PhD - Inflammation and host defense in the lung; regulation and function of secretory phospholipases A2; differential regulation of granulocyte apoptosis

Shelnes, Gregory, PhD - Metabolism

Sorci-Thomas, Mary, PhD - Atherosclerosis/thrombosis, metabolism, structural biology, transgenics 

Tsang, Allen, PhD1) Infectious Diseases: Elucidate C. trachomatis-mediated MKK4 down regulation in promoting tumor metastasis, using molecular assays, high-throughput proteomics and imaging technologies to identify signaling networks in the developmental cycle of Chlamydia infections. 2) Redox Biology: Mapping phosphorylation events associated with oxidative and radiation damage response; the effect of these events on cell cycle regulation; Clinical proteomics to identify potential targets in cancer therapy.

Yammani, Raghunatha, PhD- S100 proteins and cartilage physiology; Role of S100A4 in the development of osteoarthritis

Zhu, Xue Wei, PhD

Molecular Medicine Associate Faculty

Andersson, Karl-Erik, MD, PhD

Antinozzi, Peter, PhD

Atala, Anthony, MD - Tissue Engineering, Reconstructive Urology, Stem cells

Brosnihan, K. Bridget, PhD, MS – Role of Ang 1-7 in normal pregnancy and preeclampsia

Chilton, Ski, PhD  - The role of fatty acid metabolism in human diseases; function of botanical lipids as   dietary supplements

DuBose, Thomas, MD (Emeritus) - Regulation of renal transporters; Potassium balance; Molecular description of transporters responsible for urinary acidification; Expression and molecular regulation of non-gastric H+,K+-ATPases in kidney and distal colon, aldosterone deficiency and excess; Renal tubular acidosis; Clinical acid-base and electrolyte disorders 

Hantgan, Roy, PhD (Emeritus) - Integrin structure and function; molecular and cellular mechanisms of blood coagulation and fibrinolysis; conformation of proteins in solution

High, Kevin P., MD - Translational research of age-related changes in immune function, termed immune senescence 

McPhail, Linda, PhD (Emeritus) - The molecular mechanisms involved in the activation of the leukocyte NADPH oxidase

Mishra, Nilamadhab, MD - Epigenetics, chromatin remodeling, transcriptional regulation, gene expression and identifying therapeutic targets by proteomics in lupus

Petrovic, Snezana, MD

Swords, W. Edward, PhD - Understanding how commensal bacteria and the host develop and maintain a mutually beneficial, symbiotic relationship; Cellular Microbiology of Airway Infections

Yoza, Barbara, PhD  - Deciphering the molecular events associated with the onset and progression of septic shock, particularly as it relates to the synthesis inflammatory mediators from cells of the blood







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Section of Molecular Medicine
North Tower
3rd Floor

Office 336-713-4259

Kay Collare
Administrative Assistant


Kay Collare
Section of Molecular Medicine
Wake Forest School of Medicine
Medical Center Boulevard
Winston-Salem, NC 27157


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