Cardiovascular Research Training Program
Training Program Faculty
Wake Forest School of Medicine
Facilities and Resources
Wake Forest University Health Sciences received $184.7 million in total costs for research from extramural grants in FY 2011-2012, of which 80% was federally funded. This ongoing success is a direct result of an active program by the administration to support, and for the faculty to embrace, new technologies and research opportunities as they emerge. The Medical School’s successful and continually-evolving research programs provide a strong and dynamic setting. The Division of Public Health Sciences brought in $33.9 million among its 3 constituent departments. Other top awardees were the Wake Forest Institute of Regenerative Medicine ($32.4 million), the Departments of Internal Medicine ($17.8 million) and Physiology and Pharmacology ($11.9 million), the Division of Surgical Sciences ($8.3 million), and the Center for Genomics and Personalized Medicine ($8.2 million).
Translational Science Institute
The Wake Forest Translational Science Institute (TSI), founded in 2007, is the hub of the research academic network within the institution focused on providing services and education for faculty to train in and conduct clinical and translational research. The goal of the TSI is to provide an innovative, efficient, and sustainable research infrastructure that speeds the translation of discoveries to improve health, in concert with our community and regional academic affiliates.
Clinical Research Unit
The TSI Clinical Research Unit provides clinical investigators with the fundamental resources and controlled environment necessary to conduct research with human subjects. The Unit exists to help investigators translate basic scientific knowledge into new or improved methods of patient care. It is the CRU’s policy to prioritize resources for pilot studies and early-career investigators.
The Clinical CV Research Training Faculty
The Clinical CV Research Training program is directed by Dr. David M. Herrington, Professor of Internal Medicine/Cardiology, Associate Professor in Public Health Sciences and Associate Director of the Center for Human Genomics. He has been actively involved in clinical trials and cardiovascular epidemiology with a focus on heart disease in women, the cardiovascular effects of estrogen and the pharmacogenetics of estrogen action. He is currently involved in genome-wide association studies searching for genetic variants associated with early and extensive subclinical atherosclerosis.
The Clinical CV Research Training program relies on a multi-disciplinary collaboration of faculty members from the Departments of Medicine/Cardiology, Public Health Sciences, Surgical Sciences, Physiology and Pharmacology and Biochemistry. Dr. Herrington is joined by the following program faculty:
- Greg Burke, MD, MSc, Professor and Chair, Public Health Sciences - chronic disease research in populations, especially cardiovascular disease
- Deborah Meyers, PhD, Professor, Pediatrics, Co-Director, Human Genomics Center, Section Head, Section on Medical Genetics, Department of Pediatrics - gene mapping in common complex diseases as well as in Mendelian disorders, gene identification in several respiratory disorders including allergic conditions, asthma and COPD
- Donald W. Bowden, MD, Professor of Biochemistry and Internal Medicine/ Endocrinology & Metabolism, Associate Director, Center for Human Genomics - a wide range of human genetic studies of both single gene disorders, cystic fibrosis, multiple endocrine neoplasia, retinitis pigmentosa, and maturity onset diabetes of the young, and complex diseases, Type 1 and Type 2 diabetes, autoimmune thyroid disease, recurrent otitis media, end stage renal disease, diabetic nephropathy, and diabetic cardiovascular disease
- Dalane Kitzman, MD, Associate Professor, Medicine/ Cardiology and Director of Echocardiography - aging of the heart, exercise physiology, diastolic dysfunction, heart failure, and echocardiography
- Lynne E. Wagenknecht, DrPH, Professor and Section Head, Section on Epidemiology, Department of Public Health Sciences - a chronic disease epidemiologist with an extensive research portfolio in the areas of cardiovascular disease and diabetes
- Eugene Bleecker, MD, Professor and Section Head of Internal Medicine/ Pulmonary and Critical Care Medicine, Co-Director of the Center for Human Genomics- inflammatory mechanisms in airways diseases, epidemiologic studies and clinical trials, respiratory as well as cardiovascular physiology in animal models and man
- K. Bridget Brosnihan, PhD, Professor of Surgical Sciences, Hypertension and Vascular Research Center and Physiology & Pharmacology - assays of angiotensin system hormones and enzymes, measurements of inflammatory markers, cytokines, and growth factors
- W. Gregory Hundley, MD, Professor of Internal Medicine/ Cardiology and Radiologic Sciences – cardiac MRI and cardiovascular cohort studies and clinical trials
- Timothy Howard, PhD, Associate Professor of Pediatrics/ Center for Human Genomics – genetic studies of pulmonary, cardiovascular, and cerebrovascular disease
- Dr. Alain Bertoni., MD, PhD, Associate Professor, Department of Epidemiology & Prevention - diabetes and its complications, cardiovascular disease, quality improvement in chronic disease, and ethnic disparities in health and healthcare