Alison Arter - Doctoral Candidate

Alison L. Arter

Alison L. Arter, BS
PhD Student (Integrative Physiology & Pharmacology Dept.)

Education:  BS – Pharmacology & Toxicology, SUNY Buffalo, Buffalo, NY (2009)
Laboratory Department: Physiology & Pharmacology, Hypertension and Vascular Research Center

Advisors: Dr. Ann Tallant & Dr. Patricia E. Gallagher

Current Research:  My research focuses on determining the molecular mechanisms for the inhibition of triple negative breast cancer growth by the heptapeptide hormone Angiotensin-(1-7), [Ang-(1-7)]. In particular, my studies evaluate the signaling pathways targeted by Ang-(1-7) to produce anti-proliferative, anti-fibrotic, anti-angiogenic and anti-metastatic effects in triple negative breast cancer models, providing support for Ang-(1-7) to serve as a novel targeted therapeutic for these patients.  

Conference Proceedings & Abstracts:
Alison L. Arter, Patricia E. Gallagher, E. Ann Tallant; “Angiotensin-(1-7) Suppresses Lung Metastasis in the 4T1 Orthotopic Mammary Carcinoma Model” (2013), Wake Forest University Division of Surgical Sciences Research Day, Poster Presentation.

Alison L. Arter, Patricia E. Gallagher, E. Ann Tallant; “Angiotensin-(1-7) Suppresses Lung Metastasis in the 4T1 Orthotopic Mammary Carcinoma Model” (2013), 2nd International Conference on Tumor Microenvironment and Cellular Stress, Corfu, Greece, Poster Presentation.

Alison L. Arter, Patricia E. Gallagher, and Ann Tallant; “Angiotensin-(1-7) attenuates triple negative breast cancer growth and progression through regulation of protein phosphatases” (2013), Wake Forest University 13th Annual Graduate Student Research Day, Poster Presentation.

Patricia E. Gallagher, Alison L. Arter, David R. Soto-Pantoja, and E. Ann Tallant; “Angiotensin-(1-7) attenuates triple negative breast cancer growth and progression through regulation of protein phosphatases” (2013), AACR Tumor Invasion & Metastasis Conference, San Diego, CA, Poster Presentation.

Alison L. Arter, Patricia E. Gallagher, and E. Ann Tallant; “Angiotensin-(1-7) attenuates the proliferation of cancer-associated fibroblasts in triple negative breast cancer” (2013), AACR Tumor Invasion & Metastasis Conference, San Diego, CA, Poster Presentation.

Alison L. Arter, Ann Tallant, and Patricia E. Gallagher; “Angiotensin-(1-7)-Mediated Inhibition of Triple Negative Breast Cancer” (2012), Wake Forest University Department of Surgical Sciences Research Day, Poster Presentation.

Alison L. Arter, Ann Tallant, and Patricia E. Gallagher; “Angiotensin-(1-7) as a First-in-Class, Targeted Inhibitor of Triple Negative Breast Cancer Growth” (2012), Charlotte Research Institute Life Sciences Conference, Charlotte, NC, Poster Presentation.

Alison L. Arter, Linda Metheny-Barlow, Patricia E. Gallagher, and E. Ann Tallant; “Angiotensin-(1-7) Inhibits Proliferative and Fibrotic Signaling Mechanisms in Triple Negative Breast Cancer” (2012), AACR 103rd Annual Meeting, Chicago, IL, Poster Presentation.

Alison L. Arter, Linda Metheny-Barlow, Patricia E. Gallagher, and E. Ann Tallant; “Angiotensin-(1-7) Inhibits Proliferative and Fibrotic Signaling Mechanisms in Triple Negative Breast Cancer” (2012), Wake Forest University 12th Annual Graduate Student Research Day, Poster Presentation.

Alison L. Arter, Katherine L. Cook, David R. Soto-Pantoja, Patricia E. Gallagher, E. Ann Tallant; “Molecular Mechanisms for the Angiotensin-(1-7)-Mediated Reduction in Triple Negative Breast Cancer” (2011), Wake Forest University Department of Surgical Sciences Research Day, Poster Presentation.

Allyson Marshall, Hossam A. Shaltout, Manisha Nautiyal, Alison L. Arter, Mark C. Chappell and Debra I. Diz; “Localization and Regulation of Angiotensin Receptor Subtypes in Sheep Solitary Tract Nucleus: Effects of In Utero Exposure to Glucocorticoid”, (2011) HBPR Meeting.

Alison L. Arter, Katherine L. Cook, David R. Soto-Pantoja, Patricia E. Gallagher, E. Ann Tallant; “Molecular Mechanisms for the Angiotensin-(1-7)-Mediated Reduction in Triple Negative Breast Cancer”, (2011) AACR 102nd Annual Meeting, Orlando, FL, Poster Presentation.

Arter AL, Tallant EA, Gallagher PE; “Molecular Mechanisms for the Angiotensin-(1-7)-Mediated Reduction in Triple Negative Breast Cancer,” (2011), Wake Forest University 11th Annual Graduate Student Research Day, Poster Presentation.

Arter AL, Tallant EA, Gallagher PE; “Molecular Mechanisms for the Angiotensin-(1-7)-Mediated Reduction in Triple Negative Breast Cancer,” (2010), Wake Forest University Department of Surgical Sciences Research Day, Poster Presentation.

Arter AL, Nautiyal M, Shaltout HA, Chappell MC, Diz DI; “Mas and AT1 Receptor Expression in Adult Sheep Dorsomedial Medulla,” (2010), Experimental Biology Meeting, Anaheim, CA, Poster Presentation.

Arter AL, Nautiyal M, Shaltout HA, Chappell MC, Diz DI; “Mas and AT1 Receptor Expression in Adult Sheep Dorsomedial Medulla,” (2009), Wake Forest University Department of Surgical Sciences Research Day, Poster Presentation.

Honors & Awards:
11/2013
Silver Award – Poster Competition, Basic Science Student
21st Annual Wake Forest University Division of Surgical Sciences Research Day
Winston-Salem, NC

9/2013
Wake Forest University Alumni Student Travel Award
2nd International Conference on Tumor Microenvironment & Cellular Stress
Corfu, Greece

3/2013
1st Place – Poster Competition
13th Annual Wake Forest University Graduate Student & Post-Doctoral Research Day
Winston-Salem, NC

1/2013
Wake Forest University Alumni Student Travel Award
AACR Tumor Invasion & Metastasis Conference
San Diego, CA

10/2012
1st Place - Graduate Student Poster Competition
Charlotte Research Institute Life Sciences Conference
Charlotte, NC

4/2012
Wake Forest University Alumni Student Travel Award

4/2011
Wake Forest University Alumni Student Travel Award

4/2011
AACR Scholar-in-Training Award Finalist

4/2010
Wake Forest University Alumni Student Travel Award

2005-2009
University at Buffalo Scholarship for Academic Excellence

 

Quick Reference

Hypertension & Vascular Research Center
Debra I. Diz, PhD
Program Director

Phone: 336-716-2150
FAX: 336-716-2456

ddiz@wakehealth.edu

Janie Marshall

Phone: 336-716-1080

jmarshal@wakehealth.edu

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Last Updated: 01-22-2014
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