NIH Sponsored Lipid Sciences Training Program
NIH Sponsored Integrative Lipid Sciences, Inflammation, and Chronic Diseases Training Program
The Integrative Lipid Sciences, Inflammation, and Chronic Diseases Training Program (hereafter referred to as "Training Program") is designed to provide research training for pre-doctoral students in the broad and expanding discipline of lipid sciences, with a particular emphasis on the relationships among lipid metabolism, inflammation, and chronic diseases.
The Training Program has 11 mentors who have primary academic appointments in four departments and will draw trainees from five different graduate programs of the Graduate School of Arts and Sciences at Wake Forest University.
The Training Program is administered by a director (Dr. John Parks) and an associate director (Dr. Gregory Shelness).
Program has evolved from the natural, ongoing collaborations and common
research interests in lipid sciences of a number of established investigators,
most of whom are located in new state-of-the-art research buildings on the
downtown campus of the Wake Forest University Health Sciences (WFUHS).
The new downtown campus is located 1.5 miles from the central medical school
campus and is part of the Wake Forest Innovation Quarter. The combination of facilities,
faculty, and other resources provides a rich and vibrant interdisciplinary
training environment for graduate students interested in focusing their
research in the area of lipid sciences and chronic disease research.
The 11 primary
training faculty or mentors drawn from the Departments of Internal Medicine (Sections on Molecular Medicine and Gerontology)
(6), Biochemistry (1), Physiology/Pharmacology
(2), and Cancer Biology (2). Several faculty also have
cross appointments in other departments. Research programs of the training
faculty are supported by additional R01 grants and a P50 Center grant.
faculty who provide particular expertise in Lipid Sciences serve as Associate
Mentors and enhance the training environment of our students. Mentors
have a common research interest in the role of lipid metabolism in the
pathogenesis of chronic diseases, including atherosclerosis, lupus, asthma,
insulin resistance/obesity, Alzheimer’s Disease, and cancer. Most mentors
are currently collaborating with at least one other mentor and are principal
investigators, co-principal investigators, and/or project leaders on NIH-funded
research projects, including R01 and Center grants. Several program faculty
members, including Drs. Chilton and Parks, are part of the Center for Botanical Lipids at WFUHS, one
of five national research centers focusing on studies of botanical products
that have been jointly funded by the National Center for Complementary and
Alternative Medicine (NCCAM) and the
Office of Dietary Supplements (ODS), both components of the National Institutes of Health (NIH).
training faculty is multidisciplinary, with research that spans basic to
translational studies. PhD students participating in the Training Program come
from four departments or programs of the Wake Forest University Graduate School of Arts
and Sciences and include:
Training for students will include traditional didactic course work, seminars, journal clubs, research meetings, ethics and professional development training, participation in cutting-edge research projects, grant writing, and scientific presentations both within the Training Program environment and at regional and national meetings. All trainees are required to write an F31 or equivalent foundation grant application during their training period. Areas of emphasis or focus for students in lipid sciences include:
- Functional genomics of lipid metabolism
- Imaging of lipid deposition
- Botanical lipids in the treatment of chronic diseases
- Macromolecular assembly of lipids
- Lipid transport biology
- Bioactive lipids in the prevention, pathogenesis, and treatment of chronic diseases
Each of these areas of focus contains at least two faculty members who will participate in the training and supervision of graduate students in a co-mentoring relationship. There is also a translational research track for students who enroll in the Molecular Medicine and Translational Science graduate program.