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ADNI-2: Alzheimer’s Disease Neuroimaging Initiative 2

ADNI-2: Alzheimer’s Disease Neuroimaging Initiative 2 – Recruitment closed


ADNI 2 builds upon the successes of earlier ADNI phases to identify the earliest signs of AD and will help define the subtle changes that may take place in the brains of older people many years before overt symptoms of the disease appear. This phase of the study includes a large number of new volunteers in the earliest stages of cognitive impairment. Our goal is to determine whether imaging of the brain (through MRI, PET and amyloid imaging scans) can help predict and monitor the onset and progression of Alzheimer’s disease. In addition to neuroimaging, the study will collect and test blood and cerebrospinal fluid to determine if biomarkers can predict and monitor the disease. Testing cerebrospinal fluid is one of the important ways to obtain vital brain information.


  • Men and Women
  • Age 55 and 90 years  


  • Blood and urine samples
  • Tests of memory and thinking skills
  • Daily functioning and behavior
  • Have 3.0 Tesla Magnetic Resonance Imaging (3T MRI) scans of your brain
  • Undergo lumbar punctures (LPs)
  • Have a study partner – a friend or relative who can accompany the volunteer to all clinic visits

 Participant Benefits

  • Memory and medical screenings at no cost to you
  • Compensation for time and travel


Last Updated: 07-13-2016
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