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The Department of Biochemistry

Welcome to the Department of Biochemistry, Wake Forest School of Medicine. The Department has a three-fold mission:

  • Undertake research on the molecular basis of diseases that affect humanity.
  • Train a new generation of scientists and physicians.
  • Provide a collaborative link between other biomedical sciences and more basic sciences, such as chemistry and physics. 


Wake Forest Biotech Place, location of many of the laboratories in the Department of Biochemistry and the Center for Structural Biology

The research interests of the faculty are focused in four inter-related areas:

  • Signal transduction in cancer and inflammation
  • Nucleic acid metabolism in cancer and inflammation
  • Redox biology
  • Metabolic diseases such as diabetes and atherosclerosis.

The training mission of the Department is focused on four types of trainees:


The Hanes and NRC Buildings, location of many of the laboratories in the Department of Biochemistry, the Center for Diabetes Research, and the Center for Human Genomics and Personalized Medicine Research.

The Department’s principal interdisciplinary collaborations are promoted through participation in the following Centers:

The Department has a well-developed system of shared facilities to promote research. The research space occupied by members of the Department is located in the Hanes-Nutrition Research Center (NRC) complex on the Medical Center campus and in the recently developed Wake Forest Biotech Place in the Wake Forest Innovation Quarter in downtown Winston-Salem. Travel between the Medical Center, Wake Forest Innovation Quarter, and the Wake Forest University Reynolda campus is facilitated by Medical Center van service.

Contact Information

Douglas S. Lyles, Ph.D.
Professor and Chair
(336) 716-4237 (Medical Center)
(336) 713-1280 (Biotech Place)

April Campbell
Business Administrator
(336) 716-4381 (Biotech Place)

Misty Allen
(336) 716-6775 (Biotech Place)

Connie McArthur
(336) 716-4689 (Medical Center)


Last Updated: 08-08-2016
Wake Forest Baptist Ranked among Nation’s ‘Best Hospitals’  25 Years in a Row by U.S. News & World ReportComprehensive Cancer Centers National Designation is Renewed2017-2018 Best DoctorsNursing Magnet StatusJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.

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