Skip Navigation


Chemotherapy for Soft Tissue Sarcomas

Chemotherapy is the use of powerful drugs to kill the cancer cells. It is often used for patients with soft tissue sarcoma; whether or not chemotherapy will be used as part of your treatment depends on the type of soft tissue sarcoma you have.

How will chemotherapy treat my soft tissue sarcoma?

You may receive chemotherapy at different points during your treatment:

  • Neoadjuvant chemotherapy is treatment before surgery, to shrink the tumor and make it easier to remove.
  • Adjuvant chemotherapy is given after surgery, to destroy remaining cancer cells.
  • In cases where the cancer is advanced, chemotherapy may not be able to destroy the cancer, but can offer you relief of some of the symptoms.
  • Chemotherapy may also be given in conjunction with radiation therapy.

How is chemotherapy given?

You usually receive chemotherapy in cycles. The medicine is given either orally or through an IV. You have a treatment session for a few days, often as an outpatient, then a rest period for your body to recover from the side effects. The number of treatment sessions you need depends on the type of sarcoma you have and how you respond to the treatment.

Side effects of chemotherapy

Chemotherapy is a systemic (body-wide) treatment, and can lead to unpleasant side effects, including:

  • Nausea/vomiting
  • Loss of appetite
  • Hair loss
  • Mouth sores
  • Fatigue
  • Higher risk of infection
  • Bleeding or bruising

Side effects usually stop once the chemotherapy is over. However, there are long-term side effects of chemotherapy. For example, your fertility may be affected; if you plan to have children, discuss this with your doctor.

Learn more about chemotherapy at Wake Forest.  

Quick Reference

Comprehensive Cancer Center

1st Floor Information Desk
Appointments 336-716-WAKE
Toll-Free 888-716-WAKE

Find a Doctor Ways to Give
Last Updated: 12-08-2015
Wake Forest Baptist Ranked among Nation’s ‘Best Hospitals’  25 Years in a Row by U.S. News & World ReportComprehensive Cancer Centers National Designation is Renewed2017-2018 Best DoctorsNursing Magnet StatusJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.

© Wake Forest Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157. All Rights Reserved.