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David L. Caudell, D.V.M., Ph.D.Wake Forest School of Medicine

David L. Caudell, D.V.M., Ph.D.

Associate Professor,
Ctr for Vaccines at Extremes

Contact Information

Academic: 336-716-1621 | Department: 336-716-2011


Education & Training

  • D.V.M., Virginia PolyTechnical Institute, 2000
  • Ph.D., University of Maryland-College Park, 2008


  • Int'L Society Of Thrombosis &
  • Renal Pathology Society
  • Soc for Toxicologic Pathology
  • Am Soc for Inv Pathology
  • Am Soc of Hematology
David L. Caudell, D.V.M., Ph.D.

David L. Caudell, D.V.M., Ph.D.

Associate Professor, Pathology-Comparative Medicine
Ctr for Vaccines at Extremes
Office of Women in Medicine and Science

Research Interests

Oncogene Proteins, Fusion; Homeodomain Proteins; Immunoglobulin Class Switching; B-Lymphocytes; Mice
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Contact Information

Academic: 336-716-1621 | Department: 336-716-2011


Recent Publications

Labyrinthitis ossificans in a cynomolgus macaque (Macaca fascicularis). Balamayooran G, Atkins HM, Whitlow CT, Aycock ST, Nader MA, Cline JM, Caudell DL.. Comp Med. 2018;():.

Treatment with a selective histone deacetylase 6 inhibitor decreases lupus nephritis in NZB/W mice. Vieson MD, Gojmerac AM, Khan D, Dai R, van Duzer JH, Mazitschek R, Caudell DL, Liao X, Luo XM, Reilly CM.. Histol Histopathol. 2017;32(12):1317-1332.

Potential therapeutic action of nitrite in sickle cell disease. Wajih N, Basu S, Jailwala A, Kim HW, Ostrowski D, Perlegas A, Bolden CA, Buechler NL, Gladwin MT, Caudell DL, Rahbar E, Alexander-Miller MA, Vachharajani V, Kim-Shapiro DB.. Redox Biol. 2017;12():1026-1039.

The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia. Alexander PM, Caudell DL, Kucera GL, Pladna KM, Pardee TS.. PLoS One. 2017;12(6):e0179798.

Abdominal wall endometriosis in a rhesus macaque (Macaca mulatta). Atkins HM, Caudell DL, Hutchison AR, LeGrande AC, Kock ND.. Comp Med. 2017;67(3):277-280.

The use of African green monkeys in modeling HIV/AIDS and SIV infection [abstract]. Caudell DL, Jorgensen MJ, Kavanagh K, Kaplan JR.. J Med Primatol. 2017;46(4):193.

Specific HDAC6 inhibition by ACY-738 reduces SLE pathogenesis in NZB/W mice. Regna NL, Vieson MD, Luo XM, Chafin CB, Puthiyaveetil AG, Hammond SE, Caudell DL, Jarpe MB, Reilly CM.. Clin Immunol. 2016;162():58-73.

Prostate-specific membrane antigen-targeted liposomes specifically deliver the Zn(2+) chelator TPEN inducing oxidative stress in prostate cancer cells. Stuart CH, Singh R, Smith TL, D'Agostino R Jr, Caudell D, Balaji KC, Gmeiner WH.. Nanomedicine (Lond). 2016;11(10):1207-1222.

The applications of the novel polymeric fluoropyrimidine F10 in cancer treatment: current evidence. Gmeiner WH, Debinski W, Milligan C, Caudell D, Pardee TS.. Future Oncol. 2016;12(17):2009-2020.

Decidualization of endometriosis in macaques. Atkins HM, Lombardini ED, Caudell DL, Appt SE, Dubois A, Cline JM.. Vet Pathol. 2016;53(6):1252-1258.

Late effects of total-body gamma irradiation on cardiac structure and function in male rhesus macaques. DeBo RJ, Lees CJ, Dugan GO, Caudell DL, Michalson KT, Hanbury DB, Kavanagh K, Cline JM, Register TC.. Radiat Res. 2016;186(1):55-64.

Assessment of multiplate platelet aggregometry using citrate, heparin or hirudin in rhesus macaques. Dugan G, O'Donnell L, Hanbury DB, Cline JM, Caudell DL.. Platelets. 2015;26(8):730-735.

DMP1beta, a splice isoform of the tumour suppressor DMP1 locus, induces proliferation and progression of breast cancer. Maglic D, Stovall DB, Cline JM, Fry EA, Mallakin A, Taneja P, Caudell DL, Willingham MC, Sui G, Inoue K.. J Pathol. 2015;236(1):90-102.

Mechanisms of human erythrocytic bioactivation of nitrite. Liu C, Wajih N, Liu X, Basu S, Janes J, Marvel M, Keggi C, Helms CC, Lee AN, Belanger AM, Diz DI, Laurienti PJ, Caudell DL, Wang J, Gladwin MT, Kim-Shapiro DB.. J Biol Chem. 2015;290(2):1281-1294.

Molecular and cellular profiling of acute responses to total body radiation exposure in ovariectomized female cynomolgus macaques. DeBo RJ, Register TC, Caudell DL, Sempowski GD, Dugan G, Gray S, Owzar K, Jiang C, Bourland JD, Chao NJ, Cline JM.. Int J Radiat Biol. 2015;91(6):510-518.

Downregulation of apelin in the human placental chorionic villi from preeclamptic pregnancies. Yamaleyeva LM, Chappell MC, Brosnihan KB, Anton L, Caudell DL, Shi S, McGee C, Pirro N, Gallagher PE, Taylor RN, Merrill DC, Mertz HL.. Am J Physiol Endocrinol Metab. 2015;309(10):E852-E860.

HDAC expression and activity is upregulated in diseased lupus-prone mice. Regna NL, Vieson MD, Gojmerac AM, Luo XM, Caudell DL, Reilly CM.. Int Immunopharmacol. 2015;29(2):494-503.

MicroRNA-let-7a promotes E2F-mediated cell proliferation and NF kappa B activation in vitro. Chafin CB, Regna NL, Caudell DL, Reilly CM.. Cell Mol Immunol. 2014;11(1):79-93.

Class I and II histone deacetylase inhibition by ITF2357 reduces SLE pathogenesis in vivo. Regna NL, Chafin CB, Hammond SE, Puthiyaveetil AG, Caudell DL, Reilly CM.. Clin Immunol. 2014;151(1):29-42.

The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells. Pardee TS, Stadelman K, Jennings-Gee J, Caudell DL, Gmeiner WH.. Oncotarget. 2014;5(12):4170-4179.

The efficacy of the ribonucleotide reductase inhibitor Didox in preclinical models of AML. Cook GJ, Caudell DL, Elford HL, Pardee TS.. PLoS One. 2014;9(11):e112619.

Identification of antimullerian hormone protein expression in the arterial wall of premenopausal and postmenopausal monkeys [abstract]. Wellons M, Owens P, Caudell D, Appt SE.. Menopause. 2014;21(12):1334.

The novel ribonucleotide reductase inhibitor didox is active against AML with limited toxicities [abstract]. Cook GJ, Caudell DL, Elford HL, Pardee T.. Blood. 2012;120(21):Abstr 1513.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Associate Professor, Pathology-Comparative Medicine

David L. Caudell, D.V.M., Ph.D.

David L. Caudell, D.V.M., Ph.D.

Associate Professor, Pathology-Comparative Medicine
Ctr for Vaccines at Extremes
Office of Women in Medicine and Science

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