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Rong Chen, Ph.D.Wake Forest School of Medicine

Rong Chen, Ph.D.

Assistant Professor,

Contact Information

Academic: 336-716-8605 | Department: 336-716-2011


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Education & Training

  • B.A., East China Normal University, 1991
  • M.A., University of Kansas, 1999
  • Ph.D., University of Kansas, 2003
  • Fellowship, Public Health & General Preventive Medicine, Univ of Michigan Ann Arbor, 2009


  • Society for Neuroscience
  • Am Soc for Pharm & Exper Ther
Rong Chen, Ph.D.

Rong Chen, Ph.D.

Assistant Professor, Physiology & Pharmacology
Office of Women in Medicine and Science

Research Interests

Dopamine Plasma Membrane Transport Proteins; Dopamine; Amphetamine; Cocaine; Motor Activity
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Contact Information

Academic: 336-716-8605 | Department: 336-716-2011


Related Links

Recent Publications

Amphetamine reverses escalated cocaine intake via restoration of dopamine transporter conformation. Siciliano CA, Saha K, Calipari ES, Fordahl SC, Chen R, Khoshbouei H, Jones SR.. J Neurosci. 2018;38(2):484-497.

High and low doses of cocaine intake are differentially regulated by dopamine D2 receptors in the ventral tegmental area and the nucleus accumbens. Chen R, McIntosh S, Hemby SE, Sun H, Sexton T, Martin T, Childers SR.. Neurosci Lett. 2018;671():133-139.

Plasticity and function of spinal oxytocin and vasopressin signaling during recovery from surgery with nerve injury. Severino AL, Chen R, Hayashida K, Aschenbrenner CA, Sun H, Peters CM, Gutierrez S, Pan B, Eisenach JC.. Anesthesiology. 2018;():.

Social isolation stress increases KAPPA opioid receptor function on dopamine terminals in the nucleus accumbens of rats [abstract]. Karkhanis AN, Leussen D, Weiner JL, Chen R, Jones SR.. Alcohol. 2017;60():215.

Acute ethanol exposure attenuates 5-HT1A receptor internalization by enhancing beta-arrestin ubiquitination and subsequent degradation in N2A cells [abstract]. Luessen DJ, Sun H, McCool BA, Chen R.. Alcohol Clin Exp Res. 2017;41(Suppl 1):217A.

Chronic intermittent ethanol exposure selectively alters the expression of Galpha subunit isoforms and RGS subtypes in rat prefrontal cortex. Luessen DJ, Sun H, McGinnis MM, McCool BA, Chen R.. Brain Res. 2017;1672():106-112.

RGS2 modulates the selection of G alpha i/o subtype involved in dopamine D2 receptor signaling [abstract]. Luessen DJ, Hinshaw TP, Sun HG, Chen R.. FASEB J. 2017;31(Suppl 1):665.7.

Amphetamine self-administration alters the cholesterol content and G protein membrane compartmentalization in the rat striatum [abstract]. Hinshaw T, Yeager M, Luessen D, Sun HG, Chen R.. FASEB J. 2017;31(Suppl 1):986.2.

Supersensitive kappa opioid receptors promotes ethanol withdrawal-related behaviors and reduce dopamine signaling in the nucleus accumbens. Rose JH, Karkhanis AN, Chen R, Gioia D, Lopez MF, Becker HC, McCool BA, Jones SR.. Int J Neuropsychopharmacol. 2016;19(5):.

Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization, and regulates receptor replenishment in an agonist-biased manner. Blume LC, Leone-Kabler S, Luessen DJ, Marrs GS, Lyons E, Bass CE, Chen R, Selley DE, Howlett AC.. J Neurochem. 2016;139(3):396-407.

RGS2 modulates the activity and internalization of dopamine D2 receptors in neuroblastoma N2A cells. Luessen DJ, Hinshaw TP, Sun H, Howlett AC, Marrs G, McCool BA, Chen R.. Neuropharmacology. 2016;110(Pt A):297-307.

A single amphetamine infusion reverses deficits in dopamine nerve-terminal function caused by a history of cocaine self-administration. Ferris MJ, Calipari ES, Rose JH, Siciliano CA, Sun H, Chen R, Jones SR.. Neuropsychopharmacology. 2015;40(8):1826-1836.

Environmental enrichment and abstinence attenuate ketamine-induced cardiac and renal toxicity. Li X, Li S, Zheng W, Pan J, Huang K, Chen R, Pan T, Liao G, Chen Z, Zhou D, Shen W, Zhou W, Liu Y.. Sci Rep. 2015;5():11611.

The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration. Sun H, Calipari ES, Beveridge TJ, Jones SR, Chen R.. Neuroscience. 2015;307():253-261.

Risk of thoracic injury from direct steering wheel impact in frontal crashes. Chen R, Gabler HC.. J Trauma Acute Care Surg. 2014;76(6):1441-1446.

Amphetamine self-administration attenuates dopamine D2 autoreceptor function. Calipari ES, Sun H, Eldeeb K, Luessen DJ, Feng X, Howlett AC, Jones SR, Chen R.. Neuropsychopharmacology. 2014;39(8):1833-1842.

Dopamine transporters govern diurnal variation in extracellular dopamine tone. Ferris MJ, Espana RA, Locke JL, Konstantopoulos JK, Rose JH, Chen R, Jones SR.. Proc Natl Acad Sci U S A. 2014;111(26):E2751-2759.

Biphasic mechanisms of amphetamine action at the dopamine terminal [abstract]. Siciliano C, Calipari E, Ferris M, Chen R, Jones S.. FASEB J. 2014;28(1 Suppl):661.4.

Protein kinase C beta is a modulator of the dopamine D2 autoreceptor-activated trafficking of the dopamine transporter. Chen R, Daining CP, Sun H, Fraser R, Stokes SL, Leitges M, Gnegy ME.. J Neurochem. 2013;125(5):663-672.

G alpha i2 signaling: friend or foe in cardiac injury and heart failure?. Kaur K, Parra S, Chen R, Charbeneau RA, Wade SM, Jay PY, Neubig RR.. Naunyn Schmiedebergs Arch Pharmacol. 2012;385(5):443-453.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Assistant Professor, Physiology & Pharmacology

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