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Suzanne Craft, Ph.D.Wake Forest School of Medicine

Suzanne Craft, Ph.D.


Contact Information

Academic: 336-713-8830 | Department: 336-713-8570

Education & Training

  • B.A., University of Virginia, 1976
  • Ph.D., University of Texas-Austin, 1985
  • Internship, Clinical Neuropsychology, V.A. Medical Center(Boston), 1985
  • Fellowship, Neuropsychology, Boston University School of Me, 1986
  • Fellowship, Neuropsychology, Harvard Medical School, 1987


  • Society for Neuroscience
  • Cognitive Neuro Soc
  • Int'l Neuropsychological Soc
Suzanne Craft, Ph.D.

Suzanne Craft, Ph.D.

Professor, Gerontology and Geriatric Medicine

Research Interests

Alzheimer Disease; Insulin; Insulin Resistance; Cognition Disorders; Hypoglycemic Agents
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Contact Information

Academic: 336-713-8830 | Department: 336-713-8570

Recent Publications

Triglycerides cross the blood-brain barrier and induce central leptin and insulin receptor resistance. Banks WA, Farr SA, Salameh TS, Niehoff ML, Rhea EM, Morley JE, Hanson AJ, Hansen KM, Craft S.. Int J Obes (Lond). 2018;42(3):391-397.

The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial. Scherer RW, Drye L, Mintzer J, Lanctot K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH, Baker LD, Williamson JD, Bell RA, Espeland M, Miller ME, Mott RT, Rapp S, Hayden K,.. Trials. 2018;19(1):46.

Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums. Arnold SE, Arvanitakis Z, Macauley-Rambach SL, Koenig AM, Wang HY, Ahima RS, Craft S, Gandy S, Buettner C, Stoeckel LE, Holtzman DM, Nathan DM.. Nat Rev Neurol. 2018;14(3):168-181.

Arterial stiffness and dementia pathology: Atherosclerosis Risk in Communities (ARIC)-PET Study. Hughes TM, Wagenknecht LE, Craft S, Mintz A, Heiss G, Palta P, Wong D, Zhou Y, Knopman D, Mosley TH, Gottesman RF.. Neurology. 2018;90(14):e1248-1256.

APOE genotype influences blood to brain glucose ratio after high fat feeding [abstract]. Hanson AJ, Stewart K, Subramaniyan D, Craft S, Banks W.. J Am Geriatr Soc. 2018;66(Suppl 2):S251.

Cerebrospinal fluid and blood-based biomarkers in Alzheimer's disease and type 2 diabetes spectrum disorders. Brinkley T, Craft S. In: Srikanth V, Arvanitakis Z, eds. Type 2 diabetes and dementia. Philadelphia (PA): Elsevier;2018: 67-86.

Exploring the nexus of Alzheimer's disease and related dementias with cancer and cancer therapies: a convening of the Alzheimer's Association & Alzheimer's Drug Discovery Foundation. Snyder HM, Ahles T, Calderwood S, Carrillo MC, Chen H, Chang CH, Craft S, De Jager P, Driver JA, Fillit H, Knopman D, Lotze M, Tierney MC, Petanceska S, Saykin A, Seshadri S, Shineman D, Ganguli M.. Alzheimers Dement. 2017;13(3):267-273.

Human striatal dopaminergic and regional serotonergic synaptic degeneration with Lewy body disease and inheritance of APOE epsilon4. Postupna N, Latimer CS, Larson EB, Sherfield E, Paladin J, Shively CA, Jorgensen MJ, Andrews RN, Kaplan JR, Crane PK, Montine KS, Craft S, Keene CD, Montine TJ.. Am J Pathol. 2017;187(4):884-895.

Radiolabeling and initial biological evaluation of [18F]KBM-1 for imaging RAR-alpha receptors in neuroblastoma. Solingapuram Sai KK, Das BC, Sattiraju A, Almaguel FG, Craft S, Mintz A.. Bioorg Med Chem Lett. 2017;27(6):1425-1427.

Effects of regular and long-acting insulin on cognition and Alzheimer's disease biomarkers: a pilot clinical trial. Craft S, Claxton A, Baker LD, Hanson AJ, Cholerton B, Trittschuh EH, Dahl D, Caulder E, Neth B, Montine TJ, Jung Y, Maldjian J, Whitlow C, Friedman S.. J Alzheimers Dis. 2017;57(4):1325-1334.

Cognitive changes associated with normal and pathologic aging. Cholerton B, Reger M, Craft S. In: Halter JB, Ouslander JG, Studenski S, High KP, Asthana S, Supiano MA, Ritchie C, Hazzard WR, Woolard NF, eds. Hazzard's geriatric medicine and gerontology. 7th ed. New York: McGraw-Hill Education Medical;2017: .

Changes in metabolic risk factors over 10 years and their associations with late-life cognitive performance: the Multi-Ethnic Study of Atherosclerosis. Hughes TM, Craft S, Baker LD, Espeland MA, Rapp SR, Sink KM, Bertoni AG, Burke GL, Gottesman RF, Michos ED, Luchsinger JA, Fitzpatrick AL, Hayden KM.. Alzheimers Dement (Amst). 2017;8():18-25.

Automated synthesis of 1-[11C]acetoacetate on a TRASIS AIO module. Solingapuram Sai KK, Donald Gage H, Almaguel F, Neth B, Hughes TM, Tremblay S, Castellano CA, Cunnane SC, Jorgensen MJ, Craft S, Mintz A.. Appl Radiat Isot. 2017;129():57-61.

Blood-based bioenergetic profiling reflects differences in brain bioenergetics and metabolism. Tyrrell DJ, Bharadwaj MS, Jorgensen MJ, Register TC, Shively C, Andrews RN, Neth B, Dirk Keene C, Mintz A, Craft S, Molina AJA.. Oxid Med Cell Longev. 2017;2017():7317251.

Diabetic microvascular disease: an endocrine society scientific statement. Barrett EJ, Liu Z, Khamaisi M, King GL, Klein R, Klein BEK, Hughes TM, Craft S, Freedman BI, Bowden DW, Vinik AI, Casellini CM.. J Clin Endocrinol Metab. 2017;102(12):4343-4410.

Insulin resistance and Alzheimer's disease: bioenergetic linkages. Neth BJ, Craft S.. Front Aging Neurosci. 2017;9():345.

The role of insulin in the vascular contributions to age-related dementia. Hughes TM, Craft S.. Biochim Biophys Acta. 2016;1862(5):983-991.

Apolipoprotein E genotype and sex influence glucose tolerance in older adults: a cross-sectional study. Hanson AJ, Banks WA, Hernandez Saucedo H, Craft S.. Dement Geriatr Cogn Dis Extra. 2016;6(1):78-89.

The aging vervet as a model of Alzheimer's disease [abstract]. Latimer C, Kaplan J, Shively C, Cline J, Andrews R, Jorgensen M, Craft S, Montine T, Keene C.. J Neuropathol Exp Neurol. 2016;75(6):604.

Sex biology contributions to vulnerability to Alzheimer's disease: a think tank convened by the Women's Alzheimer's Research Initiative. Snyder HM, Asthana S, Bain L, Brinton R, Craft S, Dubal DB, Espeland MA, Gatz M, Mielke MM, Raber J, Rapp PR, Yaffe K, Carrillo MC.. Alzheimers Dement. 2016;12(11):1186-1196.

Type 2 diabetes, cognition, and dementia in older adults: toward a precision health approach. Cholerton B, Baker LD, Montine TJ, Craft S.. Diabetes Spectr. 2016;29(4):210-219.

Muscle heat shock protein 70 predicts insulin resistance with aging. Chichester L, Wylie AT, Craft S, Kavanagh K.. J Gerontol A Biol Sci Med Sci. 2015;70(2):155-162.

Insulin resistance predicts brain amyloid deposition in late middle-aged adults. Willette AA, Johnson SC, Birdsill AC, Sager MA, Christian B, Baker LD, Craft S, Oh J, Statz E, Hermann BP, Jonaitis EM, Koscik RL, La Rue A, Asthana S, Bendlin BB.. Alzheimers Dement. 2015;11(5):504-510.e1.

Long-acting intranasal insulin detemir improves cognition for adults with mild cognitive impairment or early-stage Alzheimer's disease dementia. Claxton A, Baker LD, Hanson A, Trittschuh EH, Cholerton B, Morgan A, Callaghan M, Arbuckle M, Behl C, Craft S.. J Alzheimers Dis. 2015;44(3):897-906.

The APOE genotype: modification of therapeutic responses in Alzheimer's disease. Hanson AJ, Craft S, Banks WA.. Curr Pharm Des. 2015;21(1):114-120.

Vascular contributions to cognitive impairment and dementia including Alzheimer's disease. Snyder HM, Corriveau RA, Craft S, Faber JE, Greenberg SM, Knopman D, Lamb BT, Montine TJ, Nedergaard M, Schaffer CB, Schneider JA, Wellington C, Wilcock DM, Zipfel GJ, Zlokovic B, Bain LJ, Bosetti F, Galis ZS, Koroshetz W, Carrillo MC.. Alzheimers Dement. 2015;11(6):710-717.

Review of 'the potential role of arterial stiffness in the pathogenesis of Alzheimer's disease'. Hughes TM, Craft S, Lopez OL.. Neurodegener Dis Manag. 2015;5(2):121-135.

Postmenopausal hormone therapy, type 2 diabetes mellitus, and brain volumes. Espeland MA, Brinton RD, Manson JE, Yaffe K, Hugenschmidt C, Vaughan L, Craft S, Edwards BJ, Casanova R, Masaki K, Resnick SM.. Neurology. 2015;85(13):1131-1138.

Mild cognitive impairment (MCI) in chemotherapy-treated breast cancer survivors [abstract]. Gifford A, Lawrence J, Case D, Rapp S, Baker L, Craft S, Groteluschen DL, Klepin H, Lesser G, Naughton MJ, Sachs B, Samuel TA, Sink K, Williamson, J, Shaw EG.. J Clin Oncol. 2015;33(15 Suppl):9560.

Differential effects of meal challenges on cognition, metabolism, and biomarkers for apolipoprotein E varepsilon4 carriers and adults with mild cognitive impairment. Hanson AJ, Bayer JL, Baker LD, Cholerton B, VanFossen B, Trittschuh E, Rissman RA, Donohue MC, Moghadam SH, Plymate SR, Craft S.. J Alzheimers Dis. 2015;48(1):205-218.

Oral glucose tolerance testing to modulate plasma amyloid levels: A novel biomarker. Oh ES, Marano CM, Leoutsakos JM, Lee RW, Rissman RA, Smith GS, Craft S, Lyketsos CG.. Alzheimers Dement. 2015;1(3):311-315.

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease. Turner RS, Thomas RG, Craft S, van Dyck CH, Mintzer J, Reynolds BA, Brewer JB, Rissman RA, Raman R, Aisen PS.. Neurology. 2015;85(16):1383-1391.

Impact of type 2 diabetes and postmenopausal hormone therapy on incidence of cognitive impairment in older women. Espeland MA, Brinton RD, Hugenschmidt C, Manson JE, Craft S, Yaffe K, Weitlauf J, Vaughan L, Johnson KC, Padula CB, Jackson RD, Resnick SM.. Diabetes Care. 2015;38(12):2316-2324.

Montreal cognitive assessment and modified mini mental state examination in African Americans. Sink KM, Craft S, Smith SC, Maldjian JA, Bowden DW, Xu J, Freedman BI, Divers J.. J Aging Res. 2015;2015():872018.

Associations between markers of glucose and insulin function and cognitive function in healthy African American elders. Skinner JS, Morgan A, Hernandez-Saucedo H, Hansen A, Corbett S, Arbuckle M, Leverenz JB, Wilkins CH, Craft S, Baker LD.. J Gerontol Geriatr Res. 2015;4(4):.

Enhancement of vasoreactivity and cognition by intranasal insulin in type 2 diabetes. Novak V, Milberg W, Hao Y, Munshi M, Novak P, Galica A, Manor B, Roberson P, Craft S, Abduljalil A.. Diabetes Care. 2014;37(3):751-759.

APOE genotype and gender influence glucose tolerance in older adults [abstract]. Hanson AJ, Hernandez H, Bartholomew LM, Gabrile AK, Chapman D, Craft S.. J Am Geriatr Soc. 2013;61(Suppl 1):S114.

Sex and ApoE genotype differences in treatment response to two doses of intranasal insulin in adults with mild cognitive impairment or Alzheimer's disease. Claxton A, Baker LD, Wilkinson CW, Trittschuh EH, Chapman D, Watson GS, Cholerton B, Plymate SR, Arbuckle M, Craft S.. J Alzheimers Dis. 2013;35(4):789-797.

Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence. Freiherr J, Hallschmid M, Frey WH 2nd, Brunner YF, Chapman CD, Holscher C, Craft S, De Felice FG, Benedict C.. CNS Drugs. 2013;27(7):505-514.

Neuropathologic correlates of cognition in a population-based sample. Cholerton B, Larson EB, Baker LD, Craft S, Crane PK, Millard SP, Sonnen JA, Montine TJ.. J Alzheimers Dis. 2013;36(4):699-709.

Glucose levels and risk of dementia. Crane PK, Walker R, Hubbard RA, Li G, Nathan DM, Zheng H, Haneuse S, Craft S, Montine TJ, Kahn SE, McCormick W, McCurry SM, Bowen JD, Larson EB.. N Engl J Med. 2013;369(6):540-548.

Intranasal treatment of central nervous system dysfunction in humans. Chapman CD, Frey WH II, Craft S, Danielyan L, Hallschmid M, Schioth HB, Benedict C.. Pharm Res. 2013;30(10):2475-2484.

Comparison of Montreal Cognitive Assessment (MOCA) and 3MSE scores in African-Americans [abstract]. Craft S, Smith C, Maldjian J, Freedman BI, Divers J.. Alzheimers Dement. 2013;9(4 Suppl):P321.

Aerobic exercise effects on cognition in at-risk adults: role of insulin sensitivity and APOE-epsilon 4 [abstract]. Baker L, Craft S, Cholerton B, Wilkinson C, Foster-Schubert K, McTiernan A, Williamson J, Sink K, Duncan G.. Alzheimers Dement. 2013;9(4 Suppl):P690.

Insulin, cognition, and dementia. Cholerton B, Baker LD, Craft S.. Eur J Pharmacol. 2013;719(1-3):170-179.

Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial. Hanson AJ, Bayer-Carter JL, Green PS, Montine TJ, Wilkinson CW, Baker LD, Watson GS, Bonner LM, Callaghan M, Leverenz JB, Tsai E, Postupna N, Zhang J, Lampe J, Craft S.. JAMA Neurol. 2013;70(8):972-980.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Suzanne Craft, Ph.D.

Suzanne Craft, Ph.D.

Professor, Gerontology and Geriatric Medicine

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