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Dalane W. Kitzman, M.D.Wake Forest School of Medicine

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Dalane W. Kitzman, M.D.

Professor,

Office of Research

Clinical Interests

Heart Failure, Cardiac Imaging, Stress Testing, Diastolic Dysfunction, Cardiology (clinical), Echocardiography, Geriatric Medicine and Assessment

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Education & Training

  • B.A., Johns Hopkins University, 1981
  • M.D., Johns Hopkins University School of Medicine, 1984
  • Internship, Internal Medicine, Mayo Graduate School, 1985
  • Residency, Internal Medicine, Mayo Graduate School, 1987
  • Fellowship, Duke University Hospital, 1990

Board Certifications

  • American Board of Internal Medicine, Internal Medicine

Memberships

  • Am Assn Of Clinical Anatomists
  • American College of Cardiology
  • Am Coll Of Physicians
  • Am Medical Assn
  • Am Soc Of Echocardiography
  • Am Soc Of Internal Medicine
  • Albemarle County Medical Socie
  • Forsyth Prepared Childbirth As

NPI Number

  • 1396720678
Dalane W. Kitzman, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

Dalane W. Kitzman, M.D.

Professor, Cardiology
Gerontology and Geriatric Medicine
Office of Research

Research Interests

Heart Failure; Stroke Volume; Exercise Tolerance; Oxygen Consumption; Exercise Therapy
More »

Contact Information

Request An Appointment

Academic: 336-716-3274 | Department: 336-716-3274

Media Medical Expert »

Related Links

Recent Publications

Resting and exercise haemodynamics in relation to six-minute walk test in patients with heart failure and preserved ejection fraction. Wolsk E, Kaye D, Borlaug BA, Burkhoff D, Kitzman DW, Komtebedde J, Lam CSP, Ponikowski P, Shah SJ, Gustafsson F.. Eur J Heart Fail. 2018;20(4):715-722.

Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial. Pastva AM, Duncan PW, Reeves GR, Benjamin Nelson M, Whellan DJ, O'Connor CM, Eggebeen JD, Hewston LA, Taylor KM, Mentz RJ, Rosenberg PB, Kitzman DW.. Contemp Clin Trials. 2018;64():118-127.

Influence of baseline diastolic blood pressure on effects of intensive compared with standard blood pressure control. Beddhu S, Chertow GM, Cheung AK, Cushman WC, Rahman M, Greene T, Wei G, Campbell RC, Conroy M, Freedman BI, Haley WE, Horwitz EJ, Kitzman DW, Lash J, Papademetriou V, Pisoni R, Riessen E, Rosendorff C, Watnick SG, Whittle J, Whelton PK.. Circulation. 2018;137(2):134-143.

Silent myocardial infarction and long-term risk of heart failure: the ARIC study. Qureshi WT, Zhang ZM, Chang PP, Rosamond WD, Kitzman DW, Wagenknecht LE, Soliman EZ.. J Am Coll Cardiol. 2018;71(1):1-8.

Relative impairments in hemodynamic exercise reserve parameters in heart failure with preserved ejection fraction: a study-level pooled analysis. Pandey A, Khera R, Park B, Haykowsky M, Borlaug BA, Lewis GD, Kitzman DW, Butler J, Berry JD.. JACC Heart Fail. 2018;6(2):117-126.

Evaluation of an individualized dose titration regimen of patiromer to prevent hyperkalaemia in patients with heart failure and chronic kidney disease. Pitt B, Bushinsky DA, Kitzman DW, Ruschitzka F, Metra M, Filippatos G, Rossignol P, Du Mond C, Garza D, Berman L, Lainscak M.. ESC Heart Fail. 2018;():.

Rationale and protocol of the Study of Diabetic Nephropathy with AtRasentan (SONAR) trial: a clinical trial design novel to diabetic nephropathy. Heerspink HJL, Andress DL, Bakris G, Brennan JJ, Correa-Rotter R, Dey J, Hou FF, Kitzman DW, Kohan D, Makino H, McMurray J, Perkovic V, Tobe S, Wigderson M, Parving HH, de Zeeuw D.. Diabetes Obes Metab. 2018;20(6):1369-1376.

A gift from Mary. Kitzman DW.. J Am Geriatr Soc. 2018;():.

Obesity-related heart failure with a preserved ejection fraction: the mechanistic rationale for combining inhibitors of aldosterone, neprilysin, and sodium-glucose cotransporter-2. Packer M, Kitzman DW.. JACC Heart Fail. 2018;():.

Baseline characteristics and enrichment results from the SONAR trial. Heerspink HJL, Andress DL, Bakris G, Brennan JJ, Correa-Rotter R, Hou FF, Kitzman DW, Kohan D, Makino H, McMurray J, Perkovic V, Tobe S, Wigderson M, Yi T, Parving HH, de Zeeuw D.. Diabetes Obes Metab. 2018;():.

Syncope, hypotension, and falls in the treatment of hypertension: results from the randomized clinical systolic blood pressure intervention trial. Sink KM, Evans GW, Shorr RI, Bates JT, Berlowitz D, Conroy MB, Felton DM, Gure T, Johnson KC, Kitzman D, Lyles MF, Servilla K, Supiano MA, Whittle J, Wiggers A, Fine LJ.. J Am Geriatr Soc. 2018;66(4):679-686.

Physical function, quality of life, and depression in elderly, hospitalized patients with acute decompensated heart failure with preserved versus reduced ejection fraction: analysis from the REHAB-HG trial [abstract]. Warraich H, Kitzman D, Whellan D, Pamela D, Mentz R, Pastva A, Nelson B, Reeves G.. J Am Coll Cardiol. 2018;71(11 Suppl):1877.

Impact of a multidomain intensive lifestyle intervention on complaints about memory, problem-solving, and decision-making abilities: the Action for Health in Diabetes randomized controlled clinical trial. Espeland MA, Dutton GR, Neiberg RH, Carmichael O, Hayden KM, Johnson KC, Jeffery RW, Baker LD, Cook DR, Kitzman DW, Rapp SR.. J Gerontol A Biol Sci Med Sci. 2018;():.

Therapy for heart failure with preserved ejection fraction: current status, unique challenges, and future directions. Upadhya B, Haykowsky MJ, Kitzman DW.. Heart Fail Rev. 2018;():.

Association between 6-minute walk test distance and objective variables of functional capacity after exercise training in elderly heart failure patients with preserved ejection fraction: a randomized exercise trial. Maldonado-Martin S, Brubaker PH, Eggebeen J, Stewart KP, Kitzman DW.. Arch Phys Med Rehabil. 2017;98(3):600-603.

Cardiovascular dysfunction and frailty among older adults in the community: the ARIC Study. Nadruz W Jr, Kitzman D, Windham BG, Kucharska-Newton A, Butler K, Palta P, Griswold ME, Wagenknecht LE, Heiss G, Solomon SD, Skali H, Shah AM.. J Gerontol A Biol Sci Med Sci. 2017;72(7):958-964.

New concepts in an old disease: exercise intolerance in moderate mitral stenosis [editorial comment]. Kitzman DW, Upadhya B, Zhao D.. JACC Cardiovasc Imaging. 2017;10(6):634-636.

Heart failure stages among older adults in the community: the Atherosclerosis Risk in Communities study. Shah AM, Claggett B, Loehr LR, Chang PP, Matsushita K, Kitzman D, Konety SH, Kucharska-Newton A, Sueta CA, Mosley TH Jr, Wright JD, Coresh J, Heiss G, Folsom AR, Solomon SD.. Circulation. 2017;135(3):224-240.

Contemporary assessment of left ventricular diastolic function in older adults: the Atherosclerosis Risk in Communities study. Shah AM, Claggett B, Kitzman D, Biering-Sorensen T, Jensen JS, Cheng S, Matsushita K, Konety SH, Folsom AR, Mosley TH Jr, Wright J, Heiss G, Solomon SD.. Circulation. 2017;135(5):426-439.

Race-related differences in left ventricular structural and functional remodeling in response to increased afterload: the ARIC study. Fernandes-Silva MM, Shah AM, Hegde S, Goncalves A, Claggett B, Cheng S, Nadruz W, Kitzman DW, Konety SH, Matsushita K, Mosley T, Lam CS, Borlaug BA, Solomon SD.. JACC Heart Fail. 2017;5(3):157-165.

Understanding the journey. Kitzman DW.. J Am Geriatr Soc. 2017;65(2):443.

Age- and sex-related influences on left ventricular mechanics in elderly individuals free of prevalent heart failure: the ARIC study (Atherosclerosis Risk in Communities). Hung CL, Goncalves A, Shah AM, Cheng S, Kitzman D, Solomon SD.. Circ Cardiovasc Imaging. 2017;10(1):e004510.

Cellular basis of angiotensin-(1-7)-induced augmentation of left ventricular functional performance in heart failure. Zhang X, Cheng HJ, Zhou P, Kitzman DW, Ferrario CM, Li WM, Cheng CP.. Int J Cardiol. 2017;236():405-412.

Effect of intensive blood pressure control on gait speed and mobility limitation in adults 75 years or older: a randomized clinical trial. Odden MC, Peralta CA, Berlowitz DR, Johnson KC, Whittle J, Kitzman DW, Beddhu S, Nord JW, Papademetriou V, Williamson JD, Pajewski NM.. JAMA Intern Med. 2017;177(4):500-507.

Young dads and old men. Kitzman DW.. J Am Geriatr Soc. 2017;65(6):1362-1363.

Unraveling the relationship between aging and heart failure with preserved ejection fraction: the importance of exercise and normative reference standards [editorial comment]. Kitzman DW, O'Neill TJ IV, Brubaker PH.. JACC Heart Fail. 2017;5(5):356-358.

Rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial: design and rationale. Reeves GR, Whellan DJ, Duncan P, O'Connor CM, Pastva AM, Eggebeen JD, Hewston LA, Morgan TM, Reed SD, Rejeski WJ, Mentz RJ, Rosenberg PB, Kitzman DW.. Am Heart J. 2017;185():130-139.

A novel rehabilitation intervention for older patients with acute decompensated heart failure: the REHAB-HF pilot study. Reeves GR, Whellan DJ, O'Connor CM, Duncan P, Eggebeen JD, Morgan TM, Hewston LA, Pastva A, Patel MJ, Kitzman DW.. JACC Heart Fail. 2017;5(5):359-366.

Management of heart failure with preserved ejection fraction: current challenges and future directions. Upadhya B, Kitzman DW.. Am J Cardiovasc Drugs. 2017;17(4):283-298.

Reassessing phase II heart failure clinical trials: consensus recommendations. Butler J, Hamo CE, Udelson JE, O'Connor C, Sabbah HN, Metra M, Shah SJ, Kitzman DW, Teerlink JR, Bernstein HS, Brooks G, Depre C, DeSouza MM, Dinh W, Donovan M, Frische-Danielson R, Frost RJ, Garza D, Gohring UM, Hellawell J, Hsia J,.. Circ Heart Fail. 2017;10(4):e003800.

Response to endurance exercise training in older adults with heart failure with preserved or reduced ejection fraction. Pandey A, Kitzman DW, Brubaker P, Haykowsky MJ, Morgan T, Becton JT, Berry JD.. J Am Geriatr Soc. 2017;65(8):1698-1704.

Racial differences in circulating levels of the soluble receptor for advanced glycation endproducts in middle-aged and older adults. Brinkley TE, Leng X, Nicklas BJ, Kritchevsky SB, Ding J, Kitzman DW, Hundley WG.. Metabolism. 2017;70():98-106.

Exercise training in patients with chronic heart failure and atrial fibrillation. Luo N, Merrill P, Parikh KS, Whellan DJ, Pina IL, Fiuzat M, Kraus WE, Kitzman DW, Keteyian SJ, O'Connor CM, Mentz RJ.. J Am Coll Cardiol. 2017;69(13):1683-1691.

Effect of intensive blood pressure treatment on heart failure events in the Systolic Blood Pressure Reduction Intervention Trial. Upadhya B, Rocco M, Lewis CE, Oparil S, Lovato LC, Cushman WC, Bates JT, Bello NA, Aurigemma G, Fine LJ, Johnson KC, Rodriguez CJ, Raj DS, Rastogi A, Tamariz L, Wiggers A, Kitzman DW.. Circ Heart Fail. 2017;10(4):e003613.

Effects of aging on cardiovascular structure and function. Kitzman DW, Upadhya B, Haykowsky M, Taffet GE. In: Halter JB, Ouslander JG, Studenski S, High KP, Asthana S, Supiano MA, Ritchie C, Hazzard WR, Woolard NF, eds. Hazzard's geriatric medicine and gerontology. 7th ed. New York: McGraw-Hill Education Medical;2017: .

Long-term sertraline treatment and depression effects on carotid artery atherosclerosis in premenopausal female primates. Silverstein-Metzler MG, Justice JN, Appt SE, Groban L, Kitzman DW, Carr JJ, Register TC, Shively CA.. Menopause. 2017;24(10):1175-1184.

Effect of spironolactone on exercise tolerance and arterial function in older adults with heart failure with preserved ejection fraction. Upadhya B, Hundley WG, Brubaker PH, Morgan TM, Stewart KP, Kitzman DW.. J Am Geriatr Soc. 2017;65(11):2374-2382.

Research priorities to advance the health and health care of older adults with multiple chronic conditions. Tisminetzky M, Bayliss EA, Magaziner JS, Allore HG, Anzuoni K, Boyd CM, Gill TM, Go AS, Greenspan SL, Hanson LR, Hornbrook MC, Kitzman DW, Larson EB, Naylor MD, Shirley BE, Tai-Seale M, Teri L, Tinetti ME, Whitson HE, Gurwitz JH.. J Am Geriatr Soc. 2017;65(7):1549-1553.

Physical function and exercise training in older patients with heart failure. Coats AJS, Forman DE, Haykowsky M, Kitzman DW, McNeil A, Campbell TS, Arena R.. Nat Rev Cardiol. 2017;14(9):550-559.

Heart failure with preserved ejection fraction in older adults. Upadhya B, Kitzman DW.. Heart Fail Clin. 2017;13(3):485-502.

Electrocardiographic predictors of heart failure with reduced versus preserved ejection fraction: the Multi-Ethnic Study of Atherosclerosis. O'Neal WT, Mazur M, Bertoni AG, Bluemke DA, Al-Mallah MH, Lima JAC, Kitzman D, Soliman EZ.. J Am Heart Assoc. 2017;6(6):e006023.

Prioritizing functional capacity as a principal end point for therapies oriented to older adults with cardiovascular disease: a scientific statement for healthcare professionals from the American Heart Association. Forman DE, Arena R, Boxer R, Dolansky MA, Eng JJ, Fleg JL, Haykowsky M, Jahangir A, Kaminsky LA, Kitzman DW, Lewis EF, Myers J, Reeves GR, Shen WK.. Circulation. 2017;135(16):e894-e918.

Effects of supervised exercise and dietary nitrate in older adults with controlled hypertension and/or heart failure with preserved ejection fraction. Shaltout HA, Eggebeen J, Marsh AP, Brubaker PH, Laurienti PJ, Burdette JH, Basu S, Morgan A, Dos Santos PC, Norris JL, Morgan TM, Miller GD, Rejeski WJ, Hawfield AT, Diz DI, Becton JT, Kim-Shapiro DB, Kitzman DW.. Nitric Oxide. 2017;69():78-90.

Obese heart failure with preserved ejection fraction phenotype: from pariah to central player [editorial]. Kitzman DW, Lam CSP.. Circulation. 2017;136(1):20-23.

Exercise hemodynamics and 6 minute walk distance in patients with HFpEF: importance of workload corrected pulmonary capillary wedge pressure [abstract]. Wolsk E, Kaye D, Borlaug BA, Burkhoff D, Kitzman DW, Komtebedde J, Lam CSP, Ponikowski P, Shah SJ, Gustafsson F.. Eur J Heart Fail. 2017;19(Suppl 1):328.

Making the case for skeletal muscle myopathy and its contribution to exercise intolerance in heart failure with preserved ejection fraction [editorial]. Kitzman DW, Haykowsky MJ, Tomczak CR.. Circ Heart Fail. 2017;10(7):e004281.

Subclinical atherosclerosis, cardiac and kidney function, heart failure, and dementia in the very elderly. Kuller LH, Lopez OL, Gottdiener JS, Kitzman DW, Becker JT, Chang Y, Newman AB.. J Am Heart Assoc. 2017;6(7):e005353.

Effect of intensive blood-pressure treatment on patient-reported outcomes. Berlowitz DR, Foy CG, Kazis LE, Bolin LP, Conroy MB, Fitzpatrick P, Gure TR, Kimmel PL, Kirchner K, Morisky DE, Newman J, Olney C, Oparil S, Pajewski NM, Powell J, Ramsey T, Simmons DL, Snyder J, Supiano MA, Weiner DE, Whittle J, Rocco M,.. N Engl J Med. 2017;377(8):733-744.

Utility of growth differentiation factor-15, a marker of oxidative stress and inflammation, in chronic heart failure: insights from the HF-ACTION Study. Sharma A, Stevens SR, Lucas J, Fiuzat M, Adams KF, Whellan DJ, Donahue MP, Kitzman DW, Pina IL, Zannad F, Kraus WE, O'Connor CM, Felker GM.. JACC Heart Fail. 2017;5(10):724-734.

Objectively assessed physical activity and weight loss maintenance among individuals enrolled in a lifestyle intervention. Unick JL, Gaussoin SA, Hill JO, Jakicic JM, Bond DS, Hellgren M, Johnson KC, Peters A, Coday M, Kitzman DW, Bossart S, Wing RR, Espeland MA, et al.. Obesity (Silver Spring). 2017;25(11):1903-1909.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Cardiology

Clinical Interests

Heart Failure, Cardiac Imaging, Stress Testing, Diastolic Dysfunction, Cardiology (clinical), Echocardiography, Geriatric Medicine and Assessment
Dalane W. Kitzman, M.D.

Dalane W. Kitzman, M.D.

Professor, Cardiology
Gerontology and Geriatric Medicine
Office of Research

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