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Baisong Lu, Ph.D.Wake Forest School of Medicine

Baisong Lu, Ph.D.

Assistant Professor,

Contact Information

Academic: 336-713-7276


Education & Training

  • Ph.D., China-Peoples' Liberation Army Medical Institute, 1997
  • Fellowship, Harvard University, 2000
  • Fellowship, Baylor University, 2003
Baisong Lu, Ph.D.

Baisong Lu, Ph.D.

Assistant Professor, Institute for Regenerative Medicine

Research Interests

Mitochondrial Proteins; Endopeptidases; RNA-Binding Proteins; Mutation; Mitochondria
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Contact Information

Academic: 336-713-7276


Recent Publications

Mitochondria-targeted antioxidant SkQ1 improves spermatogenesis in Immp2l mutant mice. Jiang Y, Liu C, Lei B, Xu X, Lu B.. Andrologia. 2018;50(2):e12848.

Non-viral episomal suicide construct. Lu B, Zhao Q, Yoo J, Atala A, inventors; Wake Forest University Health Sciences, assignee.. United States patent US 9870278. 2018 Jan 30. 2018;():.

No evidence of genome editing activity from Natronobacterium gregoryi Argonaute (NgAgo) in human cells. Javidi-Parsijani P, Niu G, Davis M, Lu P, Atala A, Lu B.. PLoS One. 2017;12(5):e0177444.

MEX3C interacts with adaptor-related protein complex 2 and involves in miR-451a exosomal sorting. Lu P, Li H, Li N, Singh RN, Bishop CE, Chen X, Lu B.. PLoS One. 2017;12(10):e0185992.

Developing a novel small molecule based therapy to restore hearing and balance [abstract]. Kulkarni G, Clouse C, Kim I, Lu B, Jackson J, Yoo J, Atala A.. Tissue Eng Part A. 2017;23(Suppl 1):S18.

SaCas9 mediated genome editing in mammalian cells [abstract]. Parsijani PJ, Lu B, Atala A.. Tissue Eng Part A. 2017;23(Suppl 1):S150.

The Immp2l mutation causes age-dependent degeneration of cerebellar granule neurons prevented by antioxidant treatment. Liu C, Li X, Lu B.. Aging Cell. 2016;15(1):167-176.

Oocyte-specific expression of mouse MEX3C652AA in the ovary and its potential role in regulating maternal Fos mRNA. Li X, Li Y, Liu C, Jin M, Lu B.. Biol Reprod. 2016;94(5):115.

A small molecule BIO (6-Bromoindirubin-3 '-oxim) induces adult inner ear supporting cell proliferation [abstract]. Kulkarni G, Hassan S, Kim I, Lu B, Yoo J, Jackson J, Atala A.. Tissue Eng Part A. 2016;22(Suppl 1):S91.

Expression of TAT recombinant Oct4, Sox2, Lin28, and Nanog proteins from baculovirus-infected Sf9 insect cells. Pan C, Jia W, Lu B, Bishop CE.. Gene. 2015;556(2):245-248.

Mex3c mutation reduces adiposity partially through increasing physical activity. Han C, Jiao Y, Zhao Q, Lu B.. J Endocrinol. 2014;221(3):457-468.

Small molecules and small molecule drugs in regenerative medicine. Lu B, Atala A.. Drug Discov Today. 2014;19(6):801-808.

Examination of bioenergetic function in the inner mitochondrial membrane peptidase 2-like (Immp2l) mutant mice. Bharadwaj MS, Zhou Y, Molina AJ, Criswell T, Lu B.. Redox Biol. 2014;2():1008-1015.

The role of nitric oxide signaling in food intake; insights from the inner mitochondrial membrane peptidase 2 mutant mice. Han C, Zhao Q, Lu B.. Redox Biol. 2013;1(1):498-507.

Mex3c regulates insulin-like growth factor 1 (IGF1) expression and promotes postnatal growth. Jiao Y, Bishop CE, Lu B.. Mol Biol Cell. 2012;23(8):1404-1413.

Oxidative stress is involved in age-dependent spermatogenic damage of Immp2l mutant mice. George SK, Jiao Y, Bishop CE, Lu B.. Free Radic Biol Med. 2012;52(11-12):2223-2233.

Safeguarding pluripotent stem cells for cell therapy with a non-viral, non-integrating episomal suicide construct. Zhao Q, Lu B, George SK, Yoo JJ, Atala A.. Biomaterials. 2012;33(29):7261-7271.

Mex3c mutation reduces adiposity and increases energy expenditure. Jiao Y, George SK, Zhao Q, Hulver MW, Hutson SM, Bishop CE, Lu B.. Mol Cell Biol. 2012;32(21):4350-4362.

Mitochondrial peptidase IMMP2L mutation causes early onset of age-associated disorders and impairs adult stem cell self-renewal. George SK, Jiao Y, Bishop CE, Lu B.. Aging Cell. 2011;10(4):584-594.

Deficiency in the inner mitochondrial membrane peptidase 2-like (Immp21) gene increases ischemic brain damage and impairs mitochondrial function. Ma Y, Mehta SL, Lu B, Li PA.. Neurobiol Dis. 2011;44(3):270-276.

Nervous system defects in the novel bloated bladder mouse mutant (BLAD) [abstract]. Hicks A, Lorenzetti D, Lu B, Andersson K-E, Overbeek P, Oppenheim R, Bishop C.. Soc Neurosci Abstr. 2011;2011(Neuroscience Meeting Planner):33.15.

Bladder dysfunction in a new mutant mouse model with increased superoxide--lack of nitric oxide?. Soler R, Fullhase C [Fuellhase C], Lu B, Bishop CE, Andersson K-E.. J Urol. 2010;183(2):780-785.

Reprogramming human fibroblasts using HIV-1 TAT recombinant proteins OCT4, SOX2, KLF4 and c-MYC. Pan C, Lu B, Chen H, Bishop CE.. Mol Biol Rep. 2010;37(4):2117-2124.

Increased levels of superoxide ions affects bladder function in a new mutant mouse model [abstract]. Fullhase C [Fuellhase C], Soler R, Lu B, Bishop CE, Andersson KE.. Eur Urol Suppl. 2009;8(4):176.

Bladder dysfunction in a new animal model of increased levels of superoxide ions [abstract]. Soler R, Fuellhase C, Lu B, Bishop C, Andersson K.. Neurourol Urodyn. 2009;28(7):809-810.

A mutation in the inner mitochondrial membrane peptidase 2-like gene (Immp2l) affects mitochondrial function and impairs fertility in mice. Lu B, Poirier C, Gaspar T, Gratzke C, Harrison W, Busija D, Matzuk MM, Andersson K-E, Overbeek PA, Bishop CE.. Biol Reprod. 2008;78(4):601-610.

Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Lu B, Geurts AM, Poirier C, Petit DC, Harrison W, Overbeck PA, Bishop CE.. Mamm Genome. 2007;18(5):338-346.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Baisong Lu, Ph.D.

Baisong Lu, Ph.D.

Assistant Professor, Institute for Regenerative Medicine

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