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Stephen J. Walker, Ph.D.Wake Forest School of Medicine

Stephen J. Walker, Ph.D.

Associate Professor,

Contact Information

Academic: 336-713-7272


Education & Training

  • B.A., West Virginia University, 1979
  • M.S., West Virginia University, 1982
  • Ph.D., West Virginia University, 1992
  • Fellowship, WFU School of Medicine, 1998

NPI Number

  • 1265402572
Stephen J. Walker, Ph.D.

Stephen J. Walker, Ph.D.

Associate Professor, Institute for Regenerative Medicine

Research Interests

Colitis, Ulcerative; RNA; Oligonucleotide Array Sequence Analysis; Urinary Bladder; Gene Expression
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Contact Information

Academic: 336-713-7272


Recent Publications

A human bone marrow mesodermal-derived cell population with hemogenic potential. Mokhtari S, Colletti E, Yin W, Sanada C, Lamar Z, Simmons PJ, Walker S, Bishop C, Atala A, Zanjani ED, Porada CD, Almeida-Porada G.. Leukemia. 2018;():.

Exposure of the bone marrow microenvironment to simulated solar and galactic cosmic radiation induces biological bystander effects on human hematopoiesis. Almeida-Porada G, Rodman C, Kuhlman B, Brudvik E, Moon J, George S, Guida P, Sajuthi SP, Langefeld CD, Walker SJ, Wilson PF, Porada CD.. Stem Cells Dev. 2018;():.

Evaluation of the efficacy of postmortem human bladder tissue as a normal comparator for case-controlled gene expression studies in urology. Matthews CA, Eschenroeder A, Badlani G, Evans R, Walker SJ.. Neurourol Urodyn. 2017;36(4):1076-1080.

In vitro and in vivo assessment of direct effects of simulated solar and galactic cosmic radiation on human hematopoietic stem/progenitor cells. Rodman C, Almeida-Porada G, George SK, Moon J, Soker S, Pardee T, Beaty M, Guida P, Sajuthi SP, Langefeld CD, Walker SJ, Wilson PF, Porada CD.. Leukemia. 2017;31(6):1398-1407.

Bladder capacity is a biomarker for a bladder-centric versus systemic manifestation in interstitial cystitis/bladder pain syndrome. Walker SJ, Zambon J, Andersson KE, Langefeld C, Matthews CA, Badlani G, Bowman H, Evans RJ.. J Urol. 2017;198(2):369-374.

Keratin hydrogel carrier system for simultaneous delivery of exogenous growth factors and muscle progenitor cells. Tomblyn S, Pettit Kneller EL, Walker SJ, Ellenburg MD, Kowalczewski CJ, Van Dyke M, Burnett L, Saul JM.. J Biomed Mater Res B Appl Biomater. 2016;104(5):864-879.

A putative blood-based biomarker for autism spectrum disorder-associated Ileocolitis. Walker SJ, Beavers DP, Fortunato J, Krigsman A.. Sci Rep. 2016;6():35820.

Epigenetic effects of casein-derived opioid peptides in SH-SY5Y human neuroblastoma cells. Trivedi MS, Hodgson NW, Walker SJ, Trooskens G, Nair V, Deth RC.. Nutr Metab. 2015;12():54.

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages. Yu Y, Fuscoe JC, Zhao C, Guo C, Jia M, Qing T, Bannon DI, Lancashire L, Bao W, Du T, Luo H, Su Z, Jones WD, Moland CL, Branham WS, Qian F, Ning B, Li Y, Hong H, Guo L, Mei N, Shi T, Wang KY, Wolfinger RD, Nikolsky Y, Walker SJ,.. Nat Commun. 2014;5():3230.

Correlation of gene expression with bladder capacity in interstitial cystitis/bladder pain syndrome. Colaco M, Koslov DS, Keys T, Evans RJ, Badlani GH, Andersson KE, Walker SJ.. J Urol. 2014;192(4):1123-1129.

Disease-in-a-dish: the contribution of patient-specific induced pluripotent stem cell technology to regenerative rehabilitation. Mack DL, Guan X, Wagoner A, Walker SJ, Childers MK.. Am J Phys Med Rehabil. 2014;93(11 Suppl 3):S155-S168.

A comprehensive assessment of RNA-seq accuracy, reproducibility and information content by the Sequencing Quality Control Consortium. Su Z, Labaj PP, Li S, Thierry-Mieg J, Thierry-Mieg D, Shi W, Wang C, Schroth GP, Setterquist RA, Thompson JF, Jones WD, Xiao W, Xu W, Jensen RV, Kelly R, Xu J, Conesa A, Furlanello C, Gao H, Hong H, Jafari N, Letovsky S, Liao Y, Lu F, Oakeley EJ,.. Nat Biotechnol. 2014;32(9):903-914.

Transcriptome analysis of bladder biopsy from interstitial cystitis/bladder pain syndrome patients. Walker SJ, Colaco M, Koslov DS, Keys T, Evans RJ, Badlani GH, Andersson KE.. Genom Data. 2014;2():366-368.

Identification of unique gene expression profile in children with regressive autism spectrum disorder (ASD) and ileocolitis. Walker SJ, Fortunato J, Gonzalez LG, Krigsman A.. PLoS One. 2013;8(3):e58058.

Role of the GI tract in neuroepigenetic regulation during early development and its implications for autism. Deth RC, Hodgson NW, Walker S, Krigsman A, Trivedi MS. In: Arranga T, Viadro C, Underwood L, Herbert MR, eds. Bugs, bowels, and behavior: the groundbreaking story of the gut-brain connection. New York: Skyhorse Publishing;2013: 187-195.

Cloned, CD117 selected human amniotic fluid stem cells are capable of modulating the immune response. Moorefield EC, McKee EE, Solchaga L, Orlando G, Yoo JJ, Walker S, Furth ME, Bishop CE.. PLoS ONE. 2011;6(10):e26535.

Functional muscle analysis of the Tcap knockout mouse. Markert CD, Meaney MP, Voelker KA, Grange RW, Dalley HW, Cann JK, Ahmed M, Bishwokarma B, Walker SJ, Childers MK, et al.. Hum Mol Genet. 2010;19(11):2268-2283.

Consistency of predictive signature genes and classifiers generated using different microarray platforms. Fan X, Lobenhofer EK, Chen M, Shi W, Huang J, Luo J, Zhang J, Walker SJ, Chu TM, Li L, et al.. Pharmacogenomics J. 2010;10(4):247-257.

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Shi L, Campbell G, Jones WD, Campagne F, Wen Z, Walker SJ, Su Z, Chu T-M, Goodsaid FM, Pusztai L, et al.. Nat Biotechnol. 2010;28(8):827-838.

Reprogramming of human somatic cells using human and animal oocytes. Chung Y, Bishop CE, Treff NR, Walker SJ, Sandler VM, Becker S, Klimanskaya I, Wun W-S, Atala A, Lanza R, et al.. Cloning Stem Cells. 2009;11(2):213-223.

Cultured lymphocytes from autistic children and non-autistic siblings up-regulate heat shock protein RNA in response to thimerosal challenge. Walker SJ, Segal J, Aschner M.. Neurotoxicology. 2006;27(5):685-692.

Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project. Patterson TA, Lobenhofer EK, Fulmer-Smentek SB, Collins PJ, Chu T-M, Bao W, Fang H, Kawasaki ES, Hager J, Walker SJ, et al.. Nat Biotechnol. 2006;24(9):1140-1150.

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Shi LM, Reid LH, Jones WD, Shippy R, Warrington JA, Baker SC, Collins PJ, de Longueville F, Kawasaki ES, Walker SJ, et al.. Nat Biotechnol. 2006;24(9):1151-1161.

Alpha-synuclein polymorphism and mRNA levels associated with ethanol self-adminsitration [sic] in monkeys [abstract]. Ferguson B, Grant KA, Walker SJ.. Alcohol Clin Exp Res. 2006;30(6 Suppl):120A.

Effects of ethanol self-administration on peripheral blood gene expression in monkeys [abstract]. Walker SJ, Sutter TR, Grant KA.. Alcohol Clin Exp Res. 2006;30(6 Suppl):180A.

Microarray analysis of TNFRSF and other cytokine mRNAS differentially regulated in autistic, EBV-immortalized B-lymphocytes [abstract]. Graves JT, Walker SJ.. Neurotoxicology. 2006;27(6):1184.

Transport of ethylmercury and methylmercury in an in vitro blood-brain barrier model [abstract]. Walker SJ, Nelson A, Blaxill M, Aschner M.. Neurotoxicology. 2006;27(6):1185.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Stephen J. Walker, Ph.D.

Stephen J. Walker, Ph.D.

Associate Professor, Institute for Regenerative Medicine

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