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Jeff D. Williamson, M.D.Wake Forest School of Medicine

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Jeff D. Williamson, M.D.

Program Director,
Professor,

Ctr for Vaccines at Extremes

Office of Research

Clinical Interests

Geriatrics, Clinical Geriatrics, Geriatric Continuity Care, Dementia, Geriatric Medicine and Assessment

Contact Information

Returning Patient Appointments: 336-713-8250
Department: 336-713-8964

Insurance Accepted »

Media Medical Expert »

Education & Training

  • B.S., Emory University, 1982
  • M.D., Medical College of Georgia, 1986
  • M.H.S., Sch Hyg & PH;Johns Hopkins U, 1995
  • Internship, Internal Medicine, U Maryland Medical System, 1987
  • Residency, Internal Medicine, U Maryland Medical System, 1989
  • Fellowship, Johns Hopkins University Schoo, 1992
  • Fellowship, Johns Hopkins University Schoo, 1994

Board Certifications

  • American Board of Internal Medicine, Geriatric Medicine
  • American Board of Internal Medicine, Internal Medicine

NPI Number

  • 1508842089
Jeff D. Williamson, M.D.

Doctor Rating

No Rating Available
Why No Ratings?

Jeff D. Williamson, M.D.

Program Director, Sticht Center on Aging
Professor, Gerontology and Geriatric Medicine
Office of Women in Medicine and Science
Ctr for Vaccines at Extremes
Epidemiology & Prevention
Office of Research

Research Interests

Hypertension; Antihypertensive Agents; Cognition; Diabetes Mellitus, Type 2; Cognition Disorders
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Contact Information

Department: 336-713-8964

Media Medical Expert »

Recent Publications

Systolic blood pressure and mortality: role of reverse causation [letter]. Supiano MA, Pajewski NM, Williamson JD.. J Am Geriatr Soc. 2018;66(1):205-206.

The aspirin in reducing events in the elderly trial: statistical analysis plan. Wolfe R, Murray AM, Woods RL, Kirpach B, Gilbertson D, Shah RC, Nelson MR, Reid CM, Ernst ME, Lockery J, Donnan GA, Williamson J, McNeil JJ.. Int J Stroke. 2018;13(3):335-338.

Limitations of observational data in interpreting SPRINT results [letter]. Pajewski NM, Supiano MA, Williamson JD.. JAMA Intern Med. 2018;178(1):154-155.

Cerebral structure and cognitive performance in African Americans and European Americans with type 2 diabetes. Hsu FC, Sink KM, Hugenschmidt CE, Williamson JD, Hughes TM, Palmer ND, Xu J, Smith SC, Wagner BC, Whitlow CT, Bowden DW, Maldjian JA, Divers J, Freedman BI.. J Gerontol A Biol Sci Med Sci. 2018;73(3):407-414.

The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial. Scherer RW, Drye L, Mintzer J, Lanctot K, Rosenberg P, Herrmann N, Padala P, Brawman-Mintzer O, Burke W, Craft S, Lerner AJ, Levey A, Porsteinsson A, van Dyck CH, Baker LD, Williamson JD, Bell RA, Espeland M, Miller ME, Mott RT, Rapp S, Hayden K,.. Trials. 2018;19(1):46.

Effect of physical activity on frailty: secondary analysis of a randomized controlled trial. Trombetti A, Hars M, Hsu FC, Reid KF, Church TS, Gill TM, King AC, Liu CK, Manini TM, McDermott MM, Newman AB, Rejeski WJ, Guralnik JM, Pahor M, Fielding RA, Kritchevsky S, Brinkley T, Brubaker P, Demons J, Marsh A, Nicklas B, Sink K, Williamson J.. Ann Intern Med. 2018;168(5):309-316.

Benefits and risks of intensive blood-pressure lowering in advanced chronic kidney disease [letter]. Cheung AK, Chertow GM, Greene T, Kimmel PL, Rahman M, Reboussin D, Rocco M, Sink KM, Williamson JD.. J Intern Med. 2018;284(1):106-107.

18F-florbetapir positron emission tomography-determined cerebral beta-amyloid deposition and neurocognitive performance after cardiac surgery. Klinger RY, James OG, Borges-Neto S, Bisanar T, Li YJ, Qi W, Berger M, Terrando N, Newman MF, Doraiswamy PM, Mathew JP, Weiner MW, Aisen P, Weiner M, Aisen P, Petersen R, Jack CR Jr, Jagust W, Trojanowki JQ, Toga AW, Beckett L,.. Anesthesiology. 2018;128(4):728-744.

Reliability of a novel index of senescent cell abundance in human adipose tissue [abstract]. Raborn L, Justice J, Gregory H, Nicklas B, Ding J, Kritchevsky S, Williamson J.. J Investig Med. 2018;66(2):357.

Promoting active aging: innovation in primary care [abstract]. Callahan KE, Miller ME, Kritchevsky S, Houston D, Williamson J, Neiberg R, Rejeski WJ.. J Am Geriatr Soc. 2018;66(Suppl 2):S36.

Identifying frailty using the electronic medical record within a Medicare accountable care organization [abstract]. Pajewski NM, Lenoir K, Wells BJ, Williamson J, Callahan KE.. J Am Geriatr Soc. 2018;66(Suppl 2):S122.

A cross-sectional study of cognitive impairment and falls using MSSP-ACO data [abstract]. Roman-Ashby GM, Pajewski NM, Williamson J, Callahan KE.. J Am Geriatr Soc. 2018;66(Suppl 2):S243.

Relationships between cerebral structure and cognitive function in African Americans with type 2 diabetes. Hughes TM, Sink KM, Williamson JD, Hugenschmidt CE, Wagner BC, Whitlow CT, Xu J, Smith SC, Launer LJ, Barzilay JI, Ismail-Beigi F, Bryan RN, Hsu FC, Bowden DW, Maldjian JA, Divers J, Freedman BI.. J Diabetes Complications. 2018;():.

ACCORDION MIND: results of the observational extension of the ACCORD MIND randomised trial. Murray AM, Hsu FC, Williamson JD, Bryan RN, Gerstein HC, Sullivan MD, Miller ME, Leng I, Lovato LL, Launer LJ.. Diabetologia. 2017;60(1):69-80.

Association of 3 different antihypertensive medications with hip and pelvic fracture risk in older adults: secondary analysis of a randomized clinical trial. Puttnam R, Davis BR, Pressel SL, Whelton PK, Cushman WC, Louis GT, Margolis KL, Oparil S, Williamson J, Ghosh A, Einhorn PT, Barzilay JI.. JAMA Intern Med. 2017;177(1):67-76.

Association of brain amyloid-beta with slow gait in elderly individuals without dementia: influence of cognition and apolipoprotein E epsilon4 genotype. Nadkarni NK, Perera S, Snitz BE, Mathis CA, Price J, Williamson JD, DeKosky ST, Klunk WE, Lopez OL.. JAMA Neurol. 2017;74(1):82-90.

Applying the systolic blood pressure intervention trial results to older adults. Supiano MA, Williamson JD.. J Am Geriatr Soc. 2017;65(1):16-21.

Effect of intensive blood pressure control on gait speed and mobility limitation in adults 75 years or older: a randomized clinical trial. Odden MC, Peralta CA, Berlowitz DR, Johnson KC, Whittle J, Kitzman DW, Beddhu S, Nord JW, Papademetriou V, Williamson JD, Pajewski NM.. JAMA Intern Med. 2017;177(4):500-507.

Baseline characteristics of participants in the ASPREE (ASPirin in Reducing Events in the Elderly) study. McNeil JJ, Woods RL, Nelson MR, Murray AM, Reid CM, Kirpach B, Storey E, Shah RC, Wolfe RS, Tonkin AM, Newman AB, Williamson JD, Lockery JE, Margolis KL, Ernst ME, Abhayaratna WP, Stocks N, Fitzgerald SM, Trevaks RE, Orchard SG,.. J Gerontol A Biol Sci Med Sci. 2017;72(11):1586-1593.

Adding recognition discriminability index to the delayed recall is useful to predict conversion from mild cognitive impairment to Alzheimer's disease in the Alzheimer's disease Neuroimaging Initiative. Russo MJ, Campos J, Vazquez S, Sevlever G, Allegri RF, Sink KM, Williamson JD, Garg P.. Front Aging Neurosci. 2017;9():46.

Social participation modifies the effect of a structured physical activity program on major mobility disability among older adults: results from the LIFE study. Corbett DB, Rejeski WJ, Tudor-Locke C, Glynn NW, Kritchevsky SB, McDermott MM, Church TS, Fielding RA, Gill TM, King AC, Miller ME, Chen H, Pahor M, Manini TM, Pahor M, Guralnik JM, Leeuwenburgh C, Caudle C, Crump L, Holmes L, Lee J,.. J Gerontol B Psychol Sci Soc Sci. 2017;():.

The feasibility of walnut and extra virgin olive oil supplementation in older adults. Vitolins MZ, Blackwell CS, Williamson JD, Foy CG, Wilmoth S, Sink KM, Reynolds LM, Byington RP, Reboussin DM.. Int J Food Nutr Sci. 2017;4(1):1-6.

Associations of early kidney disease with brain magnetic resonance imaging and cognitive function in African Americans with type 2 diabetes mellitus. Freedman BI, Sink KM, Hugenschmidt CE, Hughes TM, Williamson JD, Whitlow CT, Palmer ND, Miller ME, Lovato LC, Xu J, Smith SC, Launer LJ, Barzilay JI, Cohen RM, Sullivan MD, Bryan RN, Wagner BC, Bowden DW, Maldjian JA, Divers J.. Am J Kidney Dis. 2017;70(5):627-637.

The relationship between the score on a simple measure of cognitive function and incident CVD in people with diabetes: a post-hoc epidemiological analysis from the ACCORD-MIND study. Cukierman-Yaffe T, Gerstein HC, Miller ME, Launer LJ, Williamson J, Horowitz KR, Ismail-Beigi F, Lazar RM.. J Clin Endocrinol Metab. 2017;102(9):3218-3225.

Effect of statin treatment vs usual care on primary cardiovascular prevention among older adults: the ALLHAT-LLT randomized clinical trial. Han BH, Sutin D, Williamson JD, Davis BR, Piller LB, Pervin H, Pressel SL, Blaum CS.. JAMA Intern Med. 2017;177(7):955-965.

Diabetes and cognitive decline in older adults: the Ginkgo Evaluation of Memory Study. Palta P, Carlson MC, Crum RM, Colantuoni E, Sharrett AR, Yasar S, Nahin RL, DeKosky ST, Snitz B, Lopez O, Williamson JD, Furberg CD, Rapp SR, Golden SH.. J Gerontol A Biol Sci Med Sci. 2017;73(1):123-130.

Promoting active aging in primary care [abstract]. Callahan KE, Miller ME, Kritchevsky S, Houston DK, Williamson J, Rejeski WJ.. J Am Geriatr Soc. 2017;65(Suppl 1):S36.

The Short Physical Performance Battery (SPPB) score predicts survival among older adults with acute myeloid leukemia (AML) who have achieved remission [abstract]. Saad MH, Tooze JA, Pardee TS, Williamson J, Kritchevsky S, Ellis LR, Powell BL, Klepin HD.. J Am Geriatr Soc. 2017;65(Suppl 1):S131.

Intensive blood pressure control on gait speed and mobility limitation for older adults [reply to letter]. Odden MC, Williamson JD, Pajewski NM.. JAMA Intern Med. 2017;177(9):1396.

Effect of intensive blood-pressure treatment on patient-reported outcomes. Berlowitz DR, Foy CG, Kazis LE, Bolin LP, Conroy MB, Fitzpatrick P, Gure TR, Kimmel PL, Kirchner K, Morisky DE, Newman J, Olney C, Oparil S, Pajewski NM, Powell J, Ramsey T, Simmons DL, Snyder J, Supiano MA, Weiner DE, Whittle J, Rocco M,.. N Engl J Med. 2017;377(8):733-744.

Patient-reported outcome measures (PROM) as a preoperative assessment tool. Kim S, Duncan PW, Groban L, Segal H, Abbott RM, Williamson JD.. J Anesth Perioper Med. 2017;4(6):274-281.

Development and implementation of a tool to assess patient-reported outcome measures (PROM) in preoperative setting. Kim S, Duncan PW, Groban L, Segal H, Abbott RM, Williamson JD.. Glob J Perioper Med. 2017;1(1):17-21.

Associations between anxiety and depression symptoms and cognitive testing and neuroimaging in type 2 diabetes. Raffield LM, Brenes GA, Cox AJ, Freedman BI, Hugenschmidt CE, Hsu FC, Xu J, Wagner BC, Williamson JD, Maldjian JA, Bowden DW.. J Diabetes Complications. 2016;30(1):143-149.

Brain MRI volume findings in diabetic adults with albuminuria: the ACCORD-MIND study. Barzilay JI, Morgan TM, Murray AM, Bryan RN, Williamson JD, Schnall A, Launer LJ.. J Gerontol A Biol Sci Med Sci. 2016;71(6):803-810.

Characterizing frailty status in the systolic blood pressure intervention trial. Pajewski NM, Williamson JD, Applegate WB, Berlowitz DR, Bolin LP, Chertow GM, Krousel-Wood MA, Lopez-Barrera N, Powell JR, Roumie CL, Still C, Sink KM, Tang R, Wright CB, Supiano MA.. J Gerontol A Biol Sci Med Sci. 2016;71(5):649-655.

Analysis of advanced glycation end products in the DHS Mind Study. Adams JN, Martelle SE, Raffield LM, Freedman BI, Langefeld CD, Hsu FC, Maldjian JA, Williamson JD, Hugenschmidt CE, Carr JJ, Cox AJ, Bowden DW.. J Diabetes Complications. 2016;30(2):262-268.

Dopamine pathway gene variants may modulate cognitive performance in the DHS - Mind Study. Martelle SE, Raffield LM, Palmer ND, Cox AJ, Freedman BI, Hugenschmidt CE, Williamson JD, Bowden DW.. Brain Behav. 2016;6(4):e00446.

Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged greater than or equal to 75 years: a randomized clinical trial. Williamson JD, Supiano MA, Applegate WB, Berlowitz DR, Campbell RC, Chertow GM, Fine LJ, Haley WE, Hawfield AT, Ix JH, Kitzman DW, Kostis JB, Krousel-Wood MA, Launer LJ, Oparil S, Rodriguez CJ, Roumie CL, Shorr RI, Sink KM, Wadley VG,.. JAMA. 2016;315(24):2673-2682.

Are statins beneficial when used for primary prevention in older patients? [abstract]. Sutin D, Han BH, Williamson J, Davis B, Piller L, Pervin H, Blaum C.. J Am Geriatr Soc. 2016;64(Suppl 1):S7-S8.

A potential neuroprotective association between smoking and dementia in MCI patients [abstract]. Wirth SH, Williamson J, Lovato J.. J Am Geriatr Soc. 2016;64(Suppl 1):S261-S262.

APOL1 renal-risk variants associate with reduced cerebral white matter lesion volume and increased gray matter volume. Freedman BI, Gadegbeku CA, Bryan RN, Palmer ND, Hicks PJ, Ma L, Rocco MV, Smith SC, Xu J, Whitlow CT, Wagner BC, Langefeld CD, Hawfield AT, Bates JT, Lerner AJ, Raj DS, Sadaghiani MS, Toto RD, Wright JT Jr, Bowden DW, Williamson JD, Sink KM,.. Kidney Int. 2016;90(2):440-449.

Clinical and demographic correlates of medication and visit adherence in a large randomized controlled trial. Whittle J, Yamal JM, Williamson JD, Ford CE, Probstfield JL, Beard BL, Marginean H, Hamilton BP, Suhan PS, Davis BR.. BMC Health Serv Res. 2016;16(1):236.

A call for comparative effectiveness research to learn whether routine clinical care decisions can protect from dementia and cognitive decline. Dacks PA, Armstrong JJ, Brannan SK, Carman AJ, Green AM, Kirkman MS, Krakoff LR, Kuller LH, Launer LJ, Lovestone S, Merikle E, Neumann PJ, Rockwood K, Shineman DW, Stefanacci RG, Velentgas P, Viswanathan A, Whitmer RA, Williamson JD, Fillit HM.. Alzheimers Res Ther. 2016;8():33.

Adiposity is inversely associated with hippocampal volume in African Americans and European Americans with diabetes. Hsu FC, Yuan M, Bowden DW, Xu J, Smith SC, Wagenknecht LE, Langefeld CD, Divers J, Register TC, Carr JJ, Williamson JD, Sink KM, Maldjian JA, Freedman BI.. J Diabetes Complications. 2016;30(8):1506-1512.

Effect of intensive chemotherapy on physical, cognitive, and emotional health of older adults with acute myeloid leukemia. Klepin HD, Tooze JA, Pardee TS, Ellis LR, Berenzon D, Mihalko SL, Danhauer SC, Rao AV, Wildes TM, Williamson JD, Powell BL, Kritchevsky SB.. J Am Geriatr Soc. 2016;64(10):1988-1995.

APOE genotypes associate with cognitive performance but not cerebral structure: Diabetes Heart Study MIND. Palmer Allred ND, Raffield LM, Hardy JC, Hsu FC, Divers J, Xu J, Smith SC, Hugenschmidt CE, Wagner BC, Whitlow CT, Sink KM, Maldjian JA, Williamson JD, Bowden DW, Freedman BI.. Diabetes Care. 2016;39(12):2225-2231.

Intensive vs standard blood pressure control for older adults [reply to letter]. Williamson JD, Supiano MA, Pajewski NM.. JAMA. 2016;316(18):1923.

Cortical amyloid-beta and slow gait in older adults without dementia [abstract]. Nadkarni NK, Perera S, Snitz B, Price J, Williamson J, DeKosky S, Klunk WE, Lopez OL.. Gerontologist. 2016;56(Suppl 3):335.

Cerebral structural changes in diabetic kidney disease: African American-Diabetes Heart Study MIND. Sink KM, Divers J, Whitlow CT, Palmer ND, Smith SC, Xu J, Hugenschmidt CE, Wagner BC, Williamson JD, Bowden DW, Maldjian JA, Freedman BI.. Diabetes Care. 2015;38(2):206-212.

Spatial patterns of structural brain changes in type 2 diabetic patients and their longitudinal progression with intensive control of blood glucose. Erus G, Battapady H, Zhang T, Lovato J, Miller ME, Williamson JD, Launer LJ, Bryan RN, Davatzikos C.. Diabetes Care. 2015;38(1):97-104.

All Publications

For a listing of recent publications, refer to PubMed, a service provided by the National Library of Medicine.

For a list of earlier publications, visit the Carpenter Library Publication Search.

Professor, Gerontology and Geriatric Medicine

Clinical Interests

Geriatrics, Clinical Geriatrics, Geriatric Continuity Care, Dementia, Geriatric Medicine and Assessment
Jeff D. Williamson, M.D.

Jeff D. Williamson, M.D.

Program Director, Sticht Center on Aging
Professor, Gerontology and Geriatric Medicine
Office of Women in Medicine and Science
Ctr for Vaccines at Extremes
Epidemiology & Prevention
Office of Research

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