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Precision Medicine at Wake Forest Baptist

Precision medicine is changing the landscape of cancer treatment at Wake Forest Baptist, allowing us to provide our patients with more precise, targeted therapies.Request an Appointment_orange

Using the latest DNA sequencing technology, our experienced team of oncologists and geneticists can identify the genetic makeup of a patient’s tumor and tailor treatment to the specific cancer mutations (abnormalities). Our goal is to provide the best individualized cancer therapy designed for you.  

What is Precision Medicine?

Precision medicine is a personalized approach to treating cancer based on a patient’s individual genetic makeup. While traditional methods treat cancer based on the organ in which it originated, precision medicine looks at cancer on a molecular level. Genomics is one of the main components of precision medicine. It allows us to identify the “Achilles heel” of the tumor, or the genetic drivers that cause cancer.

Once we identify a tumor’s genetic driver, we use that information to match therapies that pinpoint and destroy specific genetic abnormalities and mutations in a patient’s tumor while sparing normal cells. Genomic sequencing, a process used to determine the genetic makeup of a patient’s cancer, may reveal that medications not conventionally used for cancer can effectively treat your cancer. 

Am I a candidate for Precision Medicine?

Our personalized oncology team will determine if precision medicine may be an option by reviewing your medical history, imaging scans, lab tests and treatment history. Genomic sequencing is most often recommended for adult and pediatric patients who:  

  • Have active cancer that has failed standard treatment
  • Have a high risk of relapse or progression
  • Spend 50 percent or more of the day mobile and out of bed

What cancers can be treated with Precision Medicine?

  • Abdominal cancers like pancreatic, appendiceal and stomach cancer
  • Esophageal cancer
  • Head and Neck cancer
  • Leukemia
  • Lung cancer not successfully resected by surgery
  • Melanoma
  • Metastatic breast cancer
  • Metastatic colon cancer
  • Metastatic prostate cancer
  • Ovarian cancer

We do not use precision medicine to treat cancers that are responding to the current therapy.  


Wake Forest Baptist Ranked among Nation’s ‘Best Hospitals’  26 Years in a Row by U.S. News & World ReportComprehensive Cancer Centers National Designation is Renewed2017-2018 Best DoctorsNursing Magnet StatusJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.

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