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Cardiovascular Research & Vascular and Heart Clinical Trials

We are not satisfied with performing the latest and best treatments. We believe our team also has a responsibility to be actively involved in cardiovascular research and vascular and heart clinical trials

Improving Cardiovascular Diagnosis & Treatment Planning 

Wake Forest Baptist Medical Center has been at the forefront of heart and vascular disease care for nearly 30 years: 

  • We are the only hospital in country evaluating kidney function in patients with renal and mesenteric artery disease. Our work in this area helps us determine whether treatment such as surgical revascularization will be effective. 
  • Using shared decision-making techniques, we are exploring ways to increase our patients’ involvement in decisions about their care. Cardiovascular research has shown that this type of open dialogue can lead to better outcomes. 
  • Specialists in cardiology and cancer (cardio-oncologists) are studying heart conditions associated with certain cancer treatments in order to find new treatments using drug therapies. 

Innovative Cardiovascular Treatments 

Our cardiovascular research has played key roles in advancing the diagnosis, treatment and prevention of cardiovascular disease: 

  • Our cardiac anesthesiologists are using cardiovascular research findings to make heart surgery safer. Because of this work, our patients are less likely to experience complications, such as blood transfusions, during their procedures. 
  • We are one of a few clinical sites in the country examining gene therapy treatment for patients with complex forms of vascular disease who cannot have surgery. 
  • Wake Forest is one of a select number of hospitals testing the safety and effectiveness of new technology for treating heart valve disease. Our participation in the Medtronic CoreValve® heart clinical trial means that we can offer patients non-surgical, less-invasive techniques for implanting and replacing heart valves. 

Preventing Cardiovascular Disease: Research at Wake Forest Baptist Medical Center 

We are exploring new methods for detecting early signs of cardiovascular disease: 

  • Applying findings from landmark studies such as the National Heart, Lung and Blood Institute’s WISE (Women’s Ischemia Syndrome Evaluation) Study, we are exploring new techniques to properly diagnosis certain forms of heart disease in women. 
  • Our cardiovascular research in Cardiovascular Imaging techniques is helping predict and prevent cardiovascular events, such as heart attack
  • We are the first hospital in the country to offer cardiac rehabilitation. Our work in this area helps patients prevent future complications. Hospitals around the world are using our findings to develop rehabilitation programs of their own. 

Heart & Vascular Disease Studies in North Carolina 

Cardiovascular research at Wake Forest Baptist Medical Center is helping us learn more about complex cardiovascular conditions

Learn more about clinical trials at Wake Forest Baptist and how you can participate at


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Heart & Vascular Center
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Local 336-716-WAKE
Toll-free 888-716-WAKE

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Vascular 336-716-4151
Heart 336-716-6674

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Last Updated: 10-01-2016
Wake Forest Baptist Ranked among Nation’s ‘Best Hospitals’  26 Years in a Row by U.S. News & World ReportComprehensive Cancer Centers National Designation is Renewed2017-2018 Best DoctorsNursing Magnet StatusJoint Commission Report

Disclaimer: The information on this website is for general informational purposes only and SHOULD NOT be relied upon as a substitute for sound professional medical advice, evaluation or care from your physician or other qualified health care provider.

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