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Brian McCool, PhD

Brian McCool, PhD - Recent Publications


Gioia DA, McCool BA (2017) Strain-dependent effects of acute alcohol on synaptic vesicle recycling and post-tetanic potentiation in medial glutamate inputs to the mouse basolateral amygdala. Alcohol Clin Exp Res. doi: 10.1111/acer.13343

Gioia DA, Alexander NJ, McCool BA (2016) Differential expression of Munc13-2 produces unique synaptic phenotypes in the basolateral amygdala of C57BL/6J and DBA/2J mice.  J Neurosci. 36(43):10964-10977.

Luessen DJ, Hinshaw TP, Sun H, Howlett AC, Marrs G, McCool BA, Chen R (2016) RGS2 modulates the activity and internalization of dopamine D2 receptors in neuroblastoma N2A cells.  Neuropharmacology 110(Pt A):297-307.

Robinson SL, Alexander NJ, Bluett RJ, Patel S, McCool BA (2016) Acute and chronic ethanol exposure differentially regulate CB1 receptor function at glutamatergic synapses in the rat basolateral amygdala.  Neuropharmacology 108:474-84.

Rose JH, Karkhanis AN, Chen R, Gioia D, Lopez MF, Becker HC, McCool BA, Jones SR (2016) Supersensitive kappa opioid receptors promotes ethanol withdrawal-related behaviors and reduce dopamine signaling in the nucleus accumbens. Int J Neuropsychopharmacol. 19(5).

Morales M, McGinnis MM, McCool BA (2015) Chronic ethanol exposure increases voluntary home cage intake in adult male, but not female, Long-Evans rats. Pharmacol Biochem Behav. 139(Pt A):67-76.

Robinson SL, McCool BA (2015) Microstructural analysis of rat ethanol and water drinking patterns using a modified operant self-administration model.  Physiol Behav. 149:119-30.

Karkhanis AN, Alexander NJ, McCool BA, Weiner JL, Jones SR (2015) Chronic social isolation during adolescence augments catecholamine response to acute ethanol in the basolateral amygdala. Synapse 69(8):385-95.  

Robinson SL, McCool BA (2015) Microstructural analysis of rat ethanol and water drinking patterns using a modified operant self-administration model.Physiol Behav. 149:119-130.  

McCool BA, Chappell AM (2015) Chronic intermittent ethanol inhalation increases ethanol self-administration in both C57BL/6J and DBA/2J mice. Alcohol 49(2):111-20.   

Peterson VL, McCool BA, Hamilton DA (2015) Effects of ethanol exposure and withdrawal on dendritic morphology and spine density in the nucleus accumbens core and shell. Brain Res. 1594:125-35.   

Karkhanis AN, Locke JL, McCool BA, Weiner JL, Jones SR (2014) Social isolation rearing increases nucleus accumbens dopamine and norepinephrine responses to acute ethanol in adulthood. Alcohol Clin Exp Res. 38(11):2770-9.

McCool BA, Chappell AM (2014) Persistent enhancement of ethanol drinking following a monosodium glutamate-substitution procedure in C57BL6/J and DBA/2J mice. Alcohol 48(1):55-61.   

McCool BA, Christian DT, Fetzer JA, Chappell AM (2014) Lateral/basolateral amygdala serotonin type-2 receptors modulate operant self-administration of a sweetened ethanol solution via inhibition of principal neuron activity. Front Integr Neurosci. 8:5.   

Abrahao KP, Ariwodola OJ, Butler TR, Rau AR, Skelly MJ, Carter E, Alexander NP, McCool BA, Souza-Formigoni ML, Weiner JL (2013) Locomotor sensitization to ethanol impairs NMDA receptor-dependent synaptic plasticity in the nucleus accumbens and increases ethanol self-administration. J Neurosci. 33(11):4834-42.  

Christian DT, Alexander NJ, Diaz MR, McCool BA (2013) Thalamic glutamatergic afferents into the rat basolateral amygdala exhibit increased presynaptic glutamate function following withdrawal from chronic intermittent ethanol. Neuropharmacology 65:134-42.  

Chappell AM, Carter E, McCool BA, Weiner JL (2013) Adolescent rearing conditions influence the relationship between initial anxiety-like behavior and ethanol drinking in male Long Evans rats. Alcohol Clin Exp Res. 37(Suppl 1):E394-403.   

Christian DT, Alexander NJ, Diaz MR, Robinson S, McCool BA (2012) Chronic intermittent ethanol and withdrawal differentially modulate basolateral amygdala AMPA-type glutamate receptor function and trafficking. Neuropharmacology 62(7):2430-9.   

McCool BA, Chappell AM (2012) Using monosodium glutamate to initiate ethanol self-administration in inbred mouse strains. Addict Biol. 17(1):121-31.

McCool BA (2011) Ethanol modulation of synaptic plasticity. Neuropharmacology 61(7):1097-108.   

Diaz MR, Christian DT, Anderson NJ, McCool BA (2011) Chronic ethanol and withdrawal differentially modulate lateral/basolateral amygdala paracapsular and local GABAergic synapses. J Pharmacol Exp Ther. 337(1):162-70.  

Diaz MR, Chappell AM, Christian DT, Anderson NJ, McCool BA (2011) Dopamine D3-like receptors modulate anxiety-like behavior and regulate GABAergic transmission in the rat lateral/basolateral amygdala.Neuropsychopharmacology 36(5):1090-103.


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