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Daniel Yohannes, PhD, MBA

Daniel Yohannes, PhD, MBA - Research Support

Ongoing Research Support
2U19DA019375-06                     Lester (PI)   12/01/04-09/31/15
Nicotinic Ligands for Smoking Cessation
This program attempts to develop new principles and therapeutics for smoking cessation. The goals of the project are to investigate the role of alpha-6 neuronal nicotinic acetylcholine receptor in smoking cessation. This scientific approach will enable scientists to optimize and develop lead compounds for smoking cessation based on the selective targeting of the alpha-6 receptors.
Role: Consultant

Completed Research Support

Michael J. Fox Foundation         Yohannes (PI)   01/01/10 – 12/31/10
Development of an alpha-6 Selective Neuronal Nicotinic Receptor (NNR) Imaging Agent as a Parkinson’s Disease Biomarker
This grant seeks to identify the first selective alpha-6 containing neuronal nicotinic receptor (NNR) Positron Emission Tomography (PET) imaging agent as both a drug biomarker and a disease biomarker for striatal pathology in Parkinson's disease (PD).  
Role: PI  

Jasco Family Foundation          Yohannes (PI)   01/12/13 – 06/31/14
Development of Squaricline as an Alzheimer’s disease and Neuroinflammation Therapeutic 
This Foundation grant pursues the development of a novel cognitive enhancer based on cholinergic receptor modulation
Role: PI

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