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Cystic Fibrosis Clinic

Nationally Accredited, Multi-Specialty Health Care: The Cystic Fibrosis Adult Care Center

The Cystic Fibrosis Adult Care Center at Wake Forest Baptist Health is a comprehensive, multi-disciplinary team of doctors, nurses, nutritionists, respiratory therapists, case managers, and physical therapists that offer care for adults with cystic fibrosis. The Adult Care Center at Wake Forest Baptist Health is one of 110 Centers in the Cystic Fibrosis Care Center Network. This means that our Care Center is fully accredited by the Cystic Fibrosis Foundation ( All Care Centers, including Wake Forest, are staffed by healthcare professionals who are dedicated to providing expert care for those with Cystic Fibrosis. The Cystic Fibrosis Adult Care Center undergoes thorough review every year in order to maintain its accreditation which certifies that we deliver evidence-based, effective, and efficient multi-disciplinary health care. All Wake Forest Center patients also have access to adult and pediatric specialists in Wake Forest Baptist Health, including physician specialists in endocrinology, gastroenterology, otolaryngology, orthopedics, and other subspecialties which might be needed for complete cystic fibrosis care.

Adult Cystic Fibrosis Care Center Clinic is held every Monday afternoon from 1 to 5pm. The Adult Cystic Fibrosis Care Center is a specialty clinic which requires a physician referral to be seen. Please have your primary care physician or lung specialist call 336-716-5650 to schedule a new appointment.

Cystic Fibrosis is an Inherited Disease that Primarily Affects the Lung and Digestive System

Cystic fibrosis is caused by a defective gene resulting in a protein that no longer transports chloride and water out of cells. In cystic fibrosis, this protein does not reach the cell surface or does not function correctly resulting in the production of thick, sticky mucus.  This protein is present in the cells lining the airways of the lungs, so the airways become clogged leading to recurrent infection. This defective protein also results in the obstruction of the passageways in the pancreas which stops natural enzymes from breaking down food and absorbing certain nutrients. Individuals with cystic fibrosis have two defective genes inherited from their mother and father, one from each parent.

A person born with cystic fibrosis usually has symptoms beginning in early childhood, however, signs of the disease may not appear until adolescence or later. At present, the number of adults with cystic fibrosis is nearly equal to the number of children. This is because physicians are identifying the disease more often and because treatments are now available which have extended the usual life expectancy of individuals with cystic fibrosis into the 40’s and beyond. Therefore, it is important for health care providers to diagnose cystic fibrosis when suspected to begin effective and specialized treatment as soon as possible.

Diagnosis options include the following:

  • Sweat chloride test
  • Testing for mutations in the gene known to cause Cystic Fibrosis, CFTR
  • Sputum test
  • Stool analysis to evaluate for pancreas disease
  • Imaging techniques may be used to evaluate for lung disease and pancreatic or digestive disease.

Nationally Accredited Center for Cystic Fibrosis Clinical Trials

Cystic Fibrosis Care Center physicians participate in the Cystic Fibrosis Foundation Therapeutics Development Network (TDN, which is the largest cystic fibrosis clinical trial network in the world. The TDN is a network of accredited care centers which facilitate the clinical study of new and existing therapies for the treatment of cystic fibrosis. The Cystic Fibrosis Therapeutic Development Center at Wake Forest Baptist Health was awarded on January 1, 2015 through a competitive national site selection process. The Wake Forest Center is one of 82 Foundation-funded Centers with the qualified personnel, solid research support, and demonstrated expertise necessary to recruit study participants and conduct clinical trials. Patients from the Wake Forest Care Center and outside Cystic Fibrosis Care Centers or non-Foundation-accredited clinics are welcome to participate in clinical trials at the Wake Forest Therapeutic Development Center. For more information, please contact our nurse coordinator, Kay Koroll, at 336-716-5650.

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    Last Updated: 08-12-2016
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