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Epilepsy Research

Epilepsy often begins in childhood and can cause shortened life span, the risk of intellectual impairment and a reduced quality of life; therefore, research is extremely important. 

Researchers at Wake Forest School of Medicine (WFSM) are studying the impact of epilepsy on attention, memory, learning and behavior in children, as well as the relationships between head injuries and seizures and between brain damage and the length, outcome and treatment of epilepsy.

Current research includes studies of new medications, genetic factors and seizure behavior.

Current Faculty Members Involved in Research:

Maria Sam, MD

Cormac O'Donovan, MD

Jane Boggs, MD

Gautam Popli, MBBS


2014-Present:  ARTEMIS - A Randomized, Double-Blind, Placebo Controlled Trial Examining the Safety and Efficacy of Midazolam Intranasal Spray (USL261) for the Treatment of Intermittent Bouts of Increased Seizure Activity in the Epilepsy Monitoring Unit (EMU)  Sponsor: Upsher-Smith Laboratories

2014-Present:  An Open-label Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of SAGE-547 Injection as Adjunctive Therapy in the Treatment of Adults with Super-Refractory Status Epilepticus.  Sponsor: Sage Therapeutics

2012-Present:  MONEAD-A study on the maternal outcomes and neurodevelopmental effects of antiepileptic drugs,  Sponsor: NIH: National Institute of Neurological Disorders and Stroke; National Institute of Child Health and Human Development

2012-Present: An outcomes study to evaluate MR-guided laser ablation of epileptic foci,  Sponsor: Visualase, Inc

Contact Information: Jessica Dimos,, (336) 716-8694


Last Updated: 04-29-2016
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