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Hand / Upper Extremity / Microsurgery

Clinical Faculty: Freehill, Koman, Li, Tuohy, Wiesler
Basic Science Faculty: TL Smith, BP Smith, Danelson
Residents: Mannava, Plate, Stone
Outside Collaborators: J Foxworth, Molnar

 Peripheral nerve   

  • Repair
  • Peripheral Nervous System Response to Injury
    • Schwann Cell Activation
    • Macrophage Recruitment
    • Biological Augmentation with Growth Factor Supplementation
  • Physiology and Aging
  • Nerve Regeneration:  Keratin, Biomatrials, Acellular Nerve Allografts plus Amniotic Stem Cells
  • Nerve-Muscle Interactions and the Neuromuscular Junction

Rotator cuff 

  •  Rodent Model
  •  Mathematical modeling  
  •  Biology of Aging  
  •  Human Upper-Extremity Movement Biomechanics  

 Botulinum Neurotoxin Biology, Spasticity, and Myoneural Physiology 

  •  Therapeutic applications of botulinum neurotoxin in Orthopaedic Surgery 
  •  Mathematical modeling of muscle function  


  • Thermoregulatory mechanisms
  • Novel therapies for Raynaud's Phenomena, lupus, and vascular insufficiency of the upper extremity

Multicenter Trial of Keratin Biomaterials for Peripheral Nerve Regeneration (DOD funded)

Rat Model for Studying Brachial Plexus Birth Palsy

Clinical Trial for the Surgical Treatment of Distal Radius Fractures in the Elderly (NIH multicenter trial - Coordinating Center: University of Michigan Medical School)

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Orthopaedic Surgery

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Last Updated: 06-21-2016
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