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Salil S. Desai, PhD

Salil S. Desai, Ph.D., Associate Professor

Salil Desai is an Adjunct Professor at the Institute for Regenerative Medicine and the Associate Professor of Industrial & Systems Engineering at NC A&T State University. He directs the Integrated Nano and Bio Manufacturing Laboratory at NC A&T SU and is an affiliate faculty of the Joint School of Nanoscience and Nanoengineering between NCA&TSU and UNC Greensboro. He received his MS and PhD from the University of Pittsburgh and BS from the University of Mumbai (VJTI). He investigates nano and micro manufacturing methods towards biomedical applications including regenerative tissue engineering, drug delivery, stem cell differentiation and radiation modulation devices.

SYNOPSIS OF AREA OF INTEREST: Hybrid nano/micro and bio manufacturing, drug delivery, regenerative tissue engineering, stem cell differentiation, controlled release coatings, multiscale and multiphysics modeling, scalable additive manufacturing, product design and realization.

DETAILED AREA OF INTEREST: Desai investigates hybrid nano/micro manufacturing combining direct-write fabrication and nanoimprint lithography with applications in the areas of drug delivery, stem cell differentiation and regenerative tissue engineering. He leads a research group of graduate students that study fundamental transport phenomena for developing scalable novel nano and micro manufacturing processes. His group studies time-dependent release kinetics of microcapsules as drug delivery carriers and the selective differentiation of stem cells using multi-potent growth factors. In addition, he co-leads the Cardiovascular Devices thrust for the NSF Engineering Research Center for Revolutionizing Metallic Biomaterials which focuses on biodegradable cardiac and tracheal drug eluting stents using direct-write fabrication. His group has developed anti-bacterial biocompatible coatings using novel formulation of nanoparticulate amorphous calcium phosphate to promote osseointegration of orthopedic implants. The Integrated Nano & Bio Manufacturing Laboratory directed by Desai is a Class 1000 cleanroom that explores two broad technologies including (a) Direct Write Fabrication and (b) Nanoimprint lithography. The group’s hybrid combinatorial approach will enable the selective fabrication of nano/micro bio-structures with high aspect ratios, overhanging features and multi-material capability. His research in micro/nano and bio manufacturing has potential to revolutionize the fabrication of functionally-gradient materials (FGM), regenerative tissue scaffolds, bio-chem sensors that lead to next-generation devices and systems. In addition, his group is developing radiation modulation devices for cancer therapy. Desai is recipient of several prestigious awards including the NSF Career Award, Outstanding Young Investigator Awards from American Society of Mechanical Engineers, Society of Manufacturing Engineers, Institute of Industrial Engineers, Oak Ridge National Laboratory, Department of Defense, American Society of Engineering Education, the UNC Board of Governors Teaching Excellence Award and many others.


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Institute for Regenerative Medicine

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